Development and Research - Clinical Research Informer

Gilead partners with a cancer biotech, seeking to develop an HIV immunotherapy

Bio Pharma Dive

FEBRUARY 1, 2021

Gritstone Oncology, known for its cancer research, is drawing attention in infectious disease, signing a deal with Gilead two weeks after announcing plans to develop a coronavirus vaccine.

Development

Development Vaccination Vaccine Research

Researchers develop CRISPR-based drug candidate for microbiome targeting

Pharmaceutical Technology

MAY 12, 2023

The Technical University of Denmark (DTU) has announced that an international scientific team has developed a CRISPR-based drug candidate that targets E coli directly and leaves the microbiome intact. The research team has designed four bacterial viruses which use CRISPR technology to kill the unwanted bacteria precisely.

Development

Development Bacteria Research Drugs

ICMR invites researchers to develop evidence-based guidelines for empirical use of antibiotics

AuroBlog - Aurous Healthcare Clinical Trials blog

AUGUST 22, 2024

The Indian Council of Medical Research (ICMR) has announced a Request for Expressions of Interest (EoI) aimed at inviting researchers, academicians, and scientists to participate in the formulation of evidence-based guidelines for the empirical use of antibiotics in the management of sepsis, dental infections, and vaginal discharge.

Research

Research Development Scientist Clinical Trials

Sickle cell pipeline narrows as gene therapy developers rethink research plans

Bio Pharma Dive

FEBRUARY 23, 2023

Graphite Bio and Sangamo are stopping work on their respective sickle cell gene therapies, while Intellia revealed partner Novartis ended development of its genetic treatment for the blood disease.

Gene Therapy

Gene Therapy Gene Development Genetics

What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? This new guidance will clearly impact the clinical research field, but how? Learning Objectives: Dose-response curves and patient treatment: How do pharmacologic and toxicologic principles apply to the dosing of drugs in clinical development?

Clinical Research

As ALS research booms, one treatment center finds itself in the spotlight

Bio Pharma Dive

DECEMBER 20, 2023

The Healey center is at the front of ALS research and care, earning acclaim from patients, doctors and scientists. Still, the complexities of the disease and of drug development have brought hard-felt losses.

Research

Research Doctor Doctors Scientist

Cyagen and Neurophth partner to develop gene therapy vectors

Pharmaceutical Technology

NOVEMBER 8, 2022

Cyagen and Neurophth Therapeutics have entered a strategic partnership to jointly develop next-generation AAV gene therapy vectors for specific kinds of genetic ophthalmic ailments. Additionally, Neurophth will oversee the clinical trials and marketing of gene therapy products developed leveraging the new AAV capsids of Cyagen.

Gene Therapy

Gene Therapy Gene Development Genetics

Cancer Research UK and CRIS fund lung cancer vaccine research

Pharmaceutical Technology

MARCH 25, 2024

Cancer Research UK and the CRIS Cancer Foundation have awarded a £1.7m ($2.1m) grant for developing the lung cancer vaccine LungVax.

Vaccination

Vaccination Vaccine Research Development

Editas to cut jobs, narrow research focus in restructuring

Bio Pharma Dive

JANUARY 9, 2023

The CRISPR-focused biotech will lay off 20% of its workforce, stop development of two eye disease treatments and end some early-stage cell therapy research.

Research

Research Development

Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management.

Clinical Trials

Cloud robotics labs are accelerating drug discovery and development

Pharmaceutical Technology

OCTOBER 28, 2022

Drug discovery and development is an incredibly expensive and time-consuming process, taking between 12 and 18 years, and costing on average between $2 billion and $3 billion. Robots can improve drug discovery and development. Lab-specific industrial co-bots can carry out both complex and repetitive tasks such as liquid handling.

Development

Development Drugs Pharma Companies Life Science

Lilly and ProQR to expand genetic medicine development agreement

Pharmaceutical Technology

DECEMBER 23, 2022

Eli Lilly and Company has expanded a licencing and partnership agreement with ProQR Therapeutics to discover, develop and market new genetic medicines. The post Lilly and ProQR to expand genetic medicine development agreement appeared first on Pharmaceutical Technology.

Genetics

Genetics Medicine Development Gene Therapy

Psylo signs research deal with Daiichi Sankyo for psychiatric therapies

Pharmaceutical Technology

JUNE 23, 2023

Psylo and Daiichi Sankyo have signed a sponsored research deal to advance the development of non-hallucinogenic psychiatric therapies.

Research

Research Development

Northwestern and Case Western Reserve universities develop Huntington’s therapy

Pharmaceutical Technology

NOVEMBER 4, 2024

Researchers from Northwestern and Case Western Reserve universities have developed a polymer therapeutic to treat Huntington's disease.

Development

Development Research

Hookipa partners with Roche for cancer immunotherapy development

Pharmaceutical Technology

OCTOBER 21, 2022

Hookipa Pharma and Roche have signed a strategic partnership and licence agreement for developing HB-700 and another undisclosed arenaviral immunotherapy. Under the deal, Hookipa will carry out research and initial clinical development through Phase Ib for HB-700 to treat KRAS-mutated cancers.

Development

Development Production Licensing Licensing

Aviceda, QUB to develop next-generation glyco-immune therapeutics

Pharmaceutical Technology

APRIL 10, 2023

Aviceda Therapeutics (Aviceda) has entered into a strategic partnership with the Patrick G Johnston Centre for Cancer Research at Queen’s University Belfast (QUB) for the development of next-generation glyco-immune therapeutics. The company strengthens the translational research collaboration between the US and Ireland.

Development

Development Life Science Clinical Trials Clinical Trials

Biotechs reveal layoffs, research revamps in third quarter earnings

Bio Pharma Dive

NOVEMBER 16, 2022

Tricida, Harpoon, Freeline and three other small drug developers have this week announced plans to cut staff or to reprioritize their drug development.

Research

Research Development Drugs

InvisiShield and Gladstone partner to develop intranasal preventatives

Pharmaceutical Technology

MARCH 21, 2023

Pre-clinical-stage biotechnology firm InvisiShield Technologies has partnered with Gladstone Institutes to develop intranasal preventatives against airborne viral infections including influenza, respiratory syncytial virus (RSV) and SARS-CoV-2.

Development

Development Scientist Vaccine Vaccination

Hospital Universitario and Josep Carreras develop cell therapy for leukaemia

Pharmaceutical Technology

JANUARY 17, 2023

Spain’s Hospital Universitario 12 de Octubre researchers, along with the Josep Carreras Leukaemia Research Institute, have developed a new cell therapy based on STAb cells to treat a type of leukaemia. The Spanish Association Against Cancer (AECC) provided funding for the new STAb therapy development.

Development

Development Gene Therapy Antibody Gene

Ginkgo and Boehringer partner to develop hard-to-treat disease therapies

Pharmaceutical Technology

MAY 9, 2023

Ginkgo Bioworks and Boehringer Ingelheim have collaborated to develop breakthrough therapies for hard-to-treat diseases. The companies will use the natural product discovery capabilities of Ginkgo Bioworks to expedite the discovery and development of new therapeutic molecules to address diseases with high unmet patient needs.

Development

Development Protein Sales Production

Scientists Have Developed a Blood Test For Anxiety

AuroBlog - Aurous Healthcare Clinical Trials blog

MARCH 12, 2023

Researchers have developed a blood test to determine a person’s risk of developing anxiety, while also providing insight into its current severity and best course of treatment.

Development

Development Scientist Research Clinical Trials

Merck and Moderna partner to develop and sell cancer vaccine

Pharmaceutical Technology

OCTOBER 14, 2022

German pharmaceutical firm Merck has extended its partnership with Moderna to jointly develop and sell mRNA-4157/V940, an investigational personalised cancer vaccine (PCV). In 2016, the companies entered a strategic partnership to develop novel messenger RNA (mRNA) based PCVs.

Vaccination

Vaccination Vaccine Development Immune Response

Eisai and Washington University to develop neurodegenerative disease therapies

Pharmaceutical Technology

DECEMBER 15, 2022

Eisai has entered a comprehensive research partnership agreement with Washington University School of Medicine in St Louis, US, to develop potential new therapies for neurodegenerative ailments. Under the deal, the parties intend to develop treatments for diseases including Alzheimer’s and Parkinson’s.

Development

Development Medicine Sales Scientist

HebeCell and Logomix partner to develop PSC-NK cells

Pharmaceutical Technology

AUGUST 14, 2023

HebeCell has forged a strategic collaboration with Logomix for researching and developing gene-edited natural killer cells (NK cells).

Gene Editing

Gene Editing Development Gene Research

Magazine: Left in limbo: when pharma halts rare disease research

Pharmaceutical Technology

JULY 31, 2024

Gene therapy research is expensive. Biotechs invest millions of dollars in early research to develop therapies for conditions that might be rare. But when funds are limited and the market potential is dim, such programs are often abandoned by companies, leaving patients and investigators in a bind.

Gene Therapy

Gene Therapy Research Gene Marketing

Lilly agrees to acquire gene therapy developer Akouos for $610m

Pharmaceutical Technology

OCTOBER 19, 2022

Akouos focuses on developing adeno-associated viral gene therapies to treat inner ear conditions, including sensorineural hearing loss. The post Lilly agrees to acquire gene therapy developer Akouos for $610m appeared first on Pharmaceutical Technology. The deal comprises an acquisition value of $12.50

Gene Therapy

Gene Therapy Gene Development Genetics

Umoja and IASO partner to develop therapies for haematological malignancies

Pharmaceutical Technology

NOVEMBER 22, 2022

Umoja Biopharma has signed a research agreement with IASO Biotherapeutics (IASO Bio) to develop off-the-shelf therapies for haematological malignancies. The post Umoja and IASO partner to develop therapies for haematological malignancies appeared first on Pharmaceutical Technology.

Development

Development In-Vivo Engineer Clinical Trials

JURA Bio and Syena partner to develop TCR-based therapies

Pharmaceutical Technology

SEPTEMBER 22, 2023

JURA Bio has entered into a research collaboration with Replay cell therapy product company Syena for the development of TCR based therapies.

Development

Development Production Research

Astellas to support development of Taysha’s gene therapy programmes

Pharmaceutical Technology

OCTOBER 25, 2022

Ast ellas Pharma has announced plans to make a strategic investment to back the development of Taysha Gene Therapies’ adeno-associated virus (AAV) development programmes for Rett syndrome and giant axonal neuropathy (GAN). This would allow the companies to boost the development of new therapy options for Rett syndrome and GAN patients.

Gene Therapy

Gene Therapy Gene Development Genetics

IPC and CSIR-IMTech forge strategic partnership to advance research in microbiology

AuroBlog - Aurous Healthcare Clinical Trials blog

MAY 6, 2024

Aimed at driving innovation and progress in the field of microbiology, the Indian Pharmacopoeia Commission (IPC) and the CSIR-Institute of Microbial Technology (IMTech), Chandigarh, have joined forces towards advancing microbiological research and development for the betterment of public health.

Research

Research Development Clinical Trials Clinical Trials

NIH funds research for three experimental ALS drugs

Bio Pharma Dive

OCTOBER 6, 2023

The funding, which is part of ACT for ALS, will support expanded access studies of drugs developed by Prilenia Therapeutics, Clene Nanomedicine and Rapa Therapeutics.

Drugs

Drugs Research Development

Forge Biologics and Labcorp partner for gene therapies development

Pharmaceutical Technology

MAY 4, 2023

Forge Biologics and global life sciences company Labcorp have announced a strategic adeno-associated virus (AAV) gene therapy development and manufacturing collaboration. This will improve accessibility to services for AAV-mediated gene therapy programmes. This will improve accessibility to services for AAV-mediated gene therapy programmes.

Gene Therapy

Gene Therapy Gene Development Manufacturing

MD Anderson and Xilis partner to expedite new cancer therapies development

Pharmaceutical Technology

FEBRUARY 16, 2023

The University of Texas MD Anderson Cancer Center has entered a strategic collaboration with biotech company Xilis for advancing new technology and expediting new cancer therapy development. Under the deal, MD Anderson and Xilis aim to advance the development of drug and discovery projects using the MOS technology.

Development

Development Gene Therapy Gene Drugs

Regeneron and Sonoma Biotherapeutics partner to develop T cell therapies

Pharmaceutical Technology

MARCH 29, 2023

Regeneron Pharmaceuticals has collaborated with Sonoma Biotherapeutics to discover, develop and commercialise new regulatory T cell (Treg) therapies for autoimmune diseases. The two companies will together research and develop T cell therapies for Crohn’s disease and ulcerative colitis, as well as two other undisclosed indications.

Development

Development Gene Therapy Gene Production

Pfizer lures research chief from Roche, prompting high-level reshuffle

Bio Pharma Dive

FEBRUARY 1, 2022

William Pao led discovery and early development at the Swiss drugmaker, and will now head Pfizer's global efforts to launch new products.

Research

Research Production Development

Foundery, a new biotech venture firm, sets out to speed early immune drug research

Bio Pharma Dive

AUGUST 22, 2023

Billing itself as both a scientific and investment partner, Foundery aims to provide research grants and drug development support to researchers developing new immunotherapies.

Research

Research Drugs Development

Vertex, Verve team up to develop a gene editing drug for liver disease

Bio Pharma Dive

JULY 20, 2022

The deal, which is worth $60 million upfront, broadens Vertex’s reach into gene editing and expands Verve’s research beyond heart disease.

Gene Editing

Gene Editing Gene Development Drugs

Startup Abdera raises $110M to fuel radiopharmaceutical research

Bio Pharma Dive

APRIL 20, 2023

The company, which previously raised $32 million in Series A funding, joins a growing list of new startups working to develop targeted radiation treatments.

Research

Research Development

US to invest $3B in research quest for COVID-19 pill

Bio Pharma Dive

JUNE 18, 2021

Compared to vaccines, development of antiviral drugs for the coronavirus has progressed more slowly, although data are expected soon from Merck, Pfizer and Atea.

Research

Research Vaccination Vaccine Development

Sanofi and Queensland collaborate to build $190m research facility

Pharmaceutical Technology

DECEMBER 5, 2022

Sanofi has signed an agreement with the Queensland Government in Australia to establish a $190m (A$280m) research facility in Brisbane. The hub will connect Queensland scientists with the teams at Sanofi’s mRNA Centre of Excellence in the US and France, putting them at the front of international vaccine development and biomedical research.

Research

Research Gene Therapy Vaccination Vaccine

Yet another gene therapy developer turns to layoffs

Bio Pharma Dive

APRIL 1, 2022

Taysha Gene Therapies is narrowing its research efforts and cutting around 35% of its workforce, the latest in a series of layoffs announced by makers of genetic medicines.

Gene Therapy

Gene Therapy Gene Development Genetics

Frontotemporal dementia: the state of treatment development

Pharmaceutical Technology

FEBRUARY 20, 2023

While there is no cure to this neurodegenerative condition, academics and companies are pushing through with research that could help patients and their families. Other lines of research look at the genetic overlap between FTD and amyotrophic lateral sclerosis (ALS), which could be used in the development of treatments for both conditions.

Development

Development Gene Therapy Protein Gene

Twist rolls out TCR and CAR libraries for cell therapies development

Pharmaceutical Technology

APRIL 14, 2023

Twist Bioscience has introduced Twist T-cell receptor (TCR) and Twist chimeric antigen receptor (CAR) libraries to facilitate the development of cell therapies. Researchers will now be able to speed up the creation of tailor-made libraries that can help in identifying and developing new cell therapies.

Development

Development Gene Therapy Gene Antibody

NextCure to lay off 37% of staff, dial back research plans

Bio Pharma Dive

MARCH 21, 2024

The job cuts at the cancer drug developer will primarily impact manufacturing roles, but will touch on several other parts of the organization, the company said.

Research

Research Manufacturing Development Drugs

Gilead partners with a cancer biotech, seeking to develop an HIV immunotherapy

Researchers develop CRISPR-based drug candidate for microbiome targeting

Trending Sources

ICMR invites researchers to develop evidence-based guidelines for empirical use of antibiotics

Sickle cell pipeline narrows as gene therapy developers rethink research plans

What the FDA's New Dosage Guidance Means for the Future of Clinical Research

As ALS research booms, one treatment center finds itself in the spotlight

Cyagen and Neurophth partner to develop gene therapy vectors

Cancer Research UK and CRIS fund lung cancer vaccine research

Editas to cut jobs, narrow research focus in restructuring

Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Cloud robotics labs are accelerating drug discovery and development

Lilly and ProQR to expand genetic medicine development agreement

Psylo signs research deal with Daiichi Sankyo for psychiatric therapies

Northwestern and Case Western Reserve universities develop Huntington’s therapy

Hookipa partners with Roche for cancer immunotherapy development

Aviceda, QUB to develop next-generation glyco-immune therapeutics

Biotechs reveal layoffs, research revamps in third quarter earnings

InvisiShield and Gladstone partner to develop intranasal preventatives

Hospital Universitario and Josep Carreras develop cell therapy for leukaemia

Ginkgo and Boehringer partner to develop hard-to-treat disease therapies

Scientists Have Developed a Blood Test For Anxiety

Merck and Moderna partner to develop and sell cancer vaccine

Eisai and Washington University to develop neurodegenerative disease therapies

HebeCell and Logomix partner to develop PSC-NK cells

Magazine: Left in limbo: when pharma halts rare disease research

Lilly agrees to acquire gene therapy developer Akouos for $610m

Umoja and IASO partner to develop therapies for haematological malignancies

JURA Bio and Syena partner to develop TCR-based therapies

Astellas to support development of Taysha’s gene therapy programmes

IPC and CSIR-IMTech forge strategic partnership to advance research in microbiology

NIH funds research for three experimental ALS drugs

Forge Biologics and Labcorp partner for gene therapies development

MD Anderson and Xilis partner to expedite new cancer therapies development

Regeneron and Sonoma Biotherapeutics partner to develop T cell therapies

Pfizer lures research chief from Roche, prompting high-level reshuffle

Foundery, a new biotech venture firm, sets out to speed early immune drug research

Vertex, Verve team up to develop a gene editing drug for liver disease

Startup Abdera raises $110M to fuel radiopharmaceutical research

US to invest $3B in research quest for COVID-19 pill

Sanofi and Queensland collaborate to build $190m research facility

Yet another gene therapy developer turns to layoffs

Frontotemporal dementia: the state of treatment development

Twist rolls out TCR and CAR libraries for cell therapies development

NextCure to lay off 37% of staff, dial back research plans

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