Development, Vaccination and Vaccine - Clinical Research Informer

Moderna leads the development of mRNA vaccines in infectious diseases

Pharmaceutical Technology

JANUARY 29, 2024

The rapid sequencing of the SARS-CoV-2 and the subsequent development of mRNA vaccines led to the authorisation of the first of these vaccines in late 2020.

Vaccination

Vaccination Vaccine Development

Valneva and LimmaTech partner for shigellosis vaccine development

Pharmaceutical Technology

AUGUST 1, 2024

Valneva and LimmaTech have signed a deal to potentially develop the first marketed shigellosis vaccine.

Vaccination

Vaccination Vaccine Development Marketing

BioNTech targets infectious diseases for vaccine development

Pharmaceutical Technology

MARCH 28, 2023

Following on from its Covid-19 vaccine programmes, BioNTech has set its sights on a range of infectious diseases for vaccine development. The company saw major successes with its Covid-19 vaccine, developed in collaboration with Pfizer. In response to the lower vaccine sales forecasts, BioNTech shares opened at 3.9%

Vaccination

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US launches $5bn effort for new Covid-19 vaccines development

Pharmaceutical Technology

APRIL 11, 2023

The US government is reportedly investing more than $5bn in a programme to accelerate the development of new Covid-19 vaccines and treatments. Health experts have lent their support to the new programme as the existing vaccines may not be as effective against future virus threats.

Vaccination

Vaccination Vaccine Development Antibody

How did pharma develop a vaccine so quickly?

World of DTC Marketing

DECEMBER 29, 2020

OBSERVATION: Biologics can take a long time to develop but COVID vaccines have been in development for almost 50 years and novel approaches were used to develop these vaccines. Vaccines typically take 10 to 15 years to develop, test and release to the public. However, this is time-consuming.

Vaccination

Vaccination Vaccine Development Clinical Trials

Anivive secures funds to develop human valley fever vaccine

Pharmaceutical Technology

AUGUST 5, 2024

Anivive Lifesciences has received the NIAID contract to develop a vaccine against coccidioides, the fungus responsible for valley fever.

Vaccination

Vaccination Vaccine Development

RVAC and University of Pennsylvania to develop mRNA vaccines

Pharmaceutical Technology

MARCH 20, 2023

RVAC Medicines has announced a research collaboration with the University of Pennsylvania (Penn) for the discovery and development of mRNA vaccines. The mRNA vaccine candidates will help reduce the chances of autoimmune responses that might lead to allergic conditions or serious autoimmune diseases.

Vaccination

Vaccination Vaccine Development Allergies

WestGene wins FDA approval for mRNA vaccine to treat certain cancers

Pharmaceutical Technology

MAY 10, 2024

The FDA approved WestGene’s mRNA therapeutic cancer vaccine as mRNA cancer vaccine development rises in popularity.

FDA Approval

FDA Approval Vaccination Vaccine Development

Merck and Moderna partner to develop and sell cancer vaccine

Pharmaceutical Technology

OCTOBER 14, 2022

German pharmaceutical firm Merck has extended its partnership with Moderna to jointly develop and sell mRNA-4157/V940, an investigational personalised cancer vaccine (PCV). In 2016, the companies entered a strategic partnership to develop novel messenger RNA (mRNA) based PCVs.

Vaccination

Vaccination Vaccine Development Immune Response

Evaxion Biotech to develop new vaccines for cancer

Pharmaceutical Technology

JANUARY 25, 2024

Evaxion Biotech has announced plans to develop customised cancer vaccines by targeting a category of AI-discovered tumour antigens.

Vaccination

Vaccination Vaccine Development

Merck stops coronavirus vaccine development in surprise setback

Bio Pharma Dive

JANUARY 25, 2021

The drugmaker, one of the largest vaccine developers globally, won't move forward with either of two candidates it's been testing after disappointing data in early trials.

Vaccination

Vaccination Vaccine Development Trials

GSK and Flagship Pioneering link for new medicines and vaccines

Pharmaceutical Technology

JULY 30, 2024

GSK has announced a strategic collaboration with Flagship Pioneering for the discovery and development of medicines and vaccines.

Medicine

Medicine Vaccination Vaccine Development

XtalPi and CK Life Sciences to develop AI-driven tumour vaccine R&D platform

Pharmaceutical Technology

NOVEMBER 25, 2022

XtalPi has entered a strategic partnership with CK Life Sciences for artificial intelligence (AI)-driven tumour vaccine research and development (R&D). Under the collaboration, the companies will utilise their capabilities to co-develop a new AI tumour vaccine R&D platform.

Life Science

Life Science Vaccination Vaccine Development

Seattle institute lands $18m funding to develop RNA vaccine for chikungunya

Pharmaceutical Technology

AUGUST 3, 2023

AAHI is developing a novel RNA vaccine that overcomes manufacturing and storage limitations to increase accessibility.

RNA

RNA Vaccination Vaccine Development

Breaking barriers: Advances and challenges in therapeutic cancer vaccines

Bio Pharma Dive

APRIL 1, 2024

The development of cancer vaccines has provided some hope in the battle against cancer worldwide; however, there are still many challenges to overcome when developing these life-saving treatments.

Vaccination

Vaccination Vaccine Development

Intravacc, Primrose to advance conjugate vaccine development

Pharmaceutical Technology

MARCH 29, 2024

Intravacc and Primrose Bio have announced a strategic collaboration aimed at bolstering the conjugate vaccine development and supply.

Vaccination

Vaccination Vaccine Development

Sanofi signs mRNA vaccine development deal with IDT Australia

Pharmaceutical Technology

APRIL 16, 2024

Sanofi has signed an agreement with IDT Australia for preclinical formulation development of its messenger RNA (mRNA) vaccines.

Vaccination

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Merck, Pfizer lifted as CDC backs broader use of pneumococcal vaccines

Bio Pharma Dive

OCTOBER 24, 2024

An agency panel recommended lowering the age for routine vaccination from 65 to 50, boosting the revenue outlook for multiple shots on the market and in development.

Vaccination

Vaccination Vaccine Marketing Development

GreenLight and US NIH partner to develop Covid-19 vaccine for variants

Pharmaceutical Technology

AUGUST 1, 2022

GreenLight Biosciences has entered a partnership with the US National Institutes of Health (NIH) for the development of Covid-19 vaccines, which offer broader protection against new variants and with durable effects. They intend to develop vaccines that provide lasting immune responses compared to existing vaccines.

Vaccination

Vaccination Vaccine Development RNA

LimmaTech secures funding for vaccine technology development

Pharmaceutical Technology

FEBRUARY 2, 2024

LimmaTech announced the closing of a second round of its Series A financing, securing $3m from Tenmile for vaccine technology development.

Vaccination

Vaccination Vaccine Development

Anixa expands cancer vaccine collaboration with Cleveland Clinic

Pharmaceutical Technology

MAY 9, 2024

Anixa Biosciences has expanded its partnership with Cleveland Clinic to develop additional vaccines for cancers.

Vaccination

Vaccination Vaccine Development

BioNTech’s RNA vaccine sparks potential in pancreatic cancer

Pharmaceutical Technology

MAY 11, 2023

Results published in Nature for a personalised pancreatic cancer vaccine that uses neoantigens from patients’ tumours have lent further support to early positive signals. The vaccine, developed by BioNTech, led to half of the patients with pancreatic cancer in the Phase I trial remaining cancer-free 18 months later.

RNA

RNA Vaccination Vaccine Trials

GSK and CureVac restructure mRNA vaccine development deal

Pharmaceutical Technology

JULY 3, 2024

GSK and CureVac have announced the restructuring of their existing partnership into a new licensing agreement for mRNA vaccine candidates.

Vaccination

Vaccination Vaccine Development Licensing

SK Bioscience gains UK authorisation for SKYCovion Covid-19 vaccine

Pharmaceutical Technology

MAY 30, 2023

SK Bioscience has received marketing authorisation from the UK’s medicines and healthcare products regulatory agency (MHRA) for its Covid-19 vaccine, SKYCovion. The authorisation allows the distribution of the vaccine in Scotland, Wales and England.

Vaccination

Vaccination Vaccine Protein Medicine

Ghana becomes first country to approve Oxford’s malaria vaccine

Pharmaceutical Technology

APRIL 14, 2023

Ghana’s Food and Drug Authority (FDA) has approved R21/Matrix-M malaria vaccine in children aged 5 to 36 months, marking the first regulatory clearance for the University of Oxford-developed vaccine in any country in the world. Children between the ages of five and 36 months are at highest risk of death from malaria.

Vaccination

Vaccination Vaccine Manufacturing Containment

US FDA makes EUA changes to Pfizer-BioNTech and Moderna Covid-19 vaccines

Pharmaceutical Technology

APRIL 19, 2023

The US Food and Drug Administration (FDA) has made changes to the emergency use authorisations (EUAs) of the Pfizer -BioNTech and Moderna bivalent mRNA Covid-19 vaccines. The latest amendment aims to simplify the vaccination schedule for most people. The changes mean that the current bivalent vaccines for the original and Omicron BA.4/BA.5

Vaccination

Vaccination Vaccine Gene Therapy Gene

Evaxion partners with Afrigen Biologics to develop mRNA gonorrhea vaccine

Pharmaceutical Technology

SEPTEMBER 21, 2023

The collaboration will use Evaxion’s EDEN platform to bring an AI-designed gonorrhea mRNA vaccine to the market.

Vaccination

Vaccination Vaccine Development Marketing

‘Project NextGen’ picks new mRNA, intranasal COVID vaccines for funding

Bio Pharma Dive

OCTOBER 13, 2023

The awards, to biotechs Gritstone, Codagenix and CastleVax, are part of the program’s plan to develop vaccines with broader or longer-lasting benefits.

Vaccination

Vaccination Vaccine Development

Cancer Research UK and CRIS fund lung cancer vaccine research

Pharmaceutical Technology

MARCH 25, 2024

Cancer Research UK and the CRIS Cancer Foundation have awarded a £1.7m ($2.1m) grant for developing the lung cancer vaccine LungVax.

Vaccination

Vaccination Vaccine Research Development

Into the unknown: How quickly can vaccines be developed for Disease X

Pharmaceutical Technology

SEPTEMBER 13, 2024

R&D frameworks are in place for the next pandemic-causing pathogen, but ways to derisk development are unclear.

Development

Development Vaccination Vaccine

Breakthrough Vaccine Shows High Protection Against Drug-Resistant Superbug in Mice

AuroBlog - Aurous Healthcare Clinical Trials blog

MAY 1, 2024

Scientists have developed a vaccine against a notorious drug-resistant superbug, targeting molecules on its surface that are also found on other bacteria and fungi.

Vaccination

Vaccination Vaccine Bacteria Drugs

Brazil’s ANVISA approves Takeda’s dengue vaccine candidate Qdenga

Pharmaceutical Technology

MARCH 14, 2023

The National Health Surveillance Agency (ANVISA) in Brazil has granted approval for Takeda ’s dengue virus vaccine candidate, Qdenga (Dengue Tetravalent Vaccine [Live, Attenuated]) (TAK-003). The vaccine has received approval for preventing dengue disease in people aged four years to 60 years.

Vaccination

Vaccination Vaccine Clinical Trials Clinical Trials

HIV vaccines suffer setbacks but new approaches could turn the tide

Pharmaceutical Technology

FEBRUARY 3, 2023

Only a few weeks into the new year, the prospect of getting a successful advanced HIV vaccine shrank after the discontinuation of yet another late-stage trial. On January 18, Janssen, a Johnson & Johnson (J&J) subsidiary, stated that its vaccine was not effective in preventing HIV infections.

Vaccination

Vaccination Vaccine Antibody Trials

IAVI and Biofabri sign deal for TB vaccine candidate development

Pharmaceutical Technology

MAY 18, 2023

International non-profit research organisation IAVI and Zendal Group’s subsidiary Biofabri have signed an expanded deal to develop MTBVAC, a tuberculosis (TB) vaccine candidate. The organisation and the company initially collaborated in 2021 to advance the vaccine candidate into efficacy trials.

Vaccination

Vaccination Vaccine Development Trials

Novavax gets a lifeline with Sanofi vaccine pact

Bio Pharma Dive

MAY 10, 2024

Sanofi will ally with the under-pressure biotech, paying $500 million upfront for rights to co-commercialize Novavax’s COVID shot and develop combination influenza vaccines.

Vaccination

Vaccination Vaccine Development

BioNTech and CEPI partner to develop Mpox vaccine

Pharmaceutical Technology

SEPTEMBER 19, 2023

BioNTech has entered a strategic collaboration with the CEPI to develop mRNA-based vaccine candidates for monkeypox (Mpox ) prevention.

Vaccination

Vaccination Vaccine Development

Intravacc gets NIAID contract for intranasal gonorrhoea vaccine development

Pharmaceutical Technology

OCTOBER 6, 2022

from the US National Institutes of Health (NIH) unit National Institute of Allergy and Infectious Diseases (NIAID) to develop a prophylactic intranasal vaccine against Neisseria gonorrhoeae (NG). Leveraging its outer membrane vesicles (OMV) platform technology, Intravacc will develop the vaccine.

Vaccination

Vaccination Vaccine Development Bacterium

UK MHRA approves Takeda’s dengue vaccine Qdenga

Pharmaceutical Technology

FEBRUARY 7, 2023

The UK Medicines and Healthcare products Regulatory Agency (MHRA) has granted marketing authorisation for Takeda ’s dengue virus vaccine candidate, Qdenga (Dengue Tetravalent Vaccine [Live, Attenuated]). The vaccine candidate has been approved for active immunisation against the infection in people from four years of age.

Vaccination

Vaccination Vaccine Genetics Trials

India grants approval for Bharat Biotech’s intranasal Covid-19 vaccine

Pharmaceutical Technology

SEPTEMBER 7, 2022

Indian company Bharat Biotech International has secured approval from Central Drugs Standard Control Organisation (CDSCO) under Restricted Use in Emergency Situation for its intranasal Covid-19 vaccine, iNCOVACC (BBV154), for usage in people aged 18 years and older. It is formulated to permit intranasal delivery via nasal drops.

Vaccination

Vaccination Vaccine Clinical Trials Clinical Trials

Merck pays $250M to license Moderna cancer vaccine

Bio Pharma Dive

OCTOBER 12, 2022

The drugmaker’s decision to grab rights to the shot deepens its ties with the COVID-19 vaccine developer and comes weeks before a key data release.

Vaccination

Vaccination Vaccine Licensing Licensing

Novo Nordisk Foundation sets up airborne infection vaccine initiative

Pharmaceutical Technology

DECEMBER 18, 2023

The Novo Nordisk Foundation has invested Dkr1.8bn in the initiative to develop vaccines for various airborne infection diseases.

Vaccination

Vaccination Vaccine Development

China grants EUA to Covid-19 vaccine against XBB descendent lineages

Pharmaceutical Technology

JUNE 9, 2023

5+delta) protein vaccine (Sf9 cell). This marks the world’s first Covid-19 vaccine approved for emergency use against XBB descendent lineages of SARS-CoV-2. The vaccine has been developed by WestVac Biopharma along with the West China Medical Center and Sichuan University. recombinant Covid-19 trivalent (XBB.1.5+BA.5+delta)

Vaccination

Vaccination Vaccine Protein HR

SK bioscience and Hilleman to develop Ebola-Zaire virus vaccine

Pharmaceutical Technology

NOVEMBER 23, 2023

SK bioscience has signed an agreement with Hilleman Laboratories Singapore for the co-development of a vaccine against the Zaire Ebola virus.

Vaccination

Vaccination Vaccine Development

Indonesia grants EUA for US-developed Covid-19 vaccine

Pharmaceutical Technology

OCTOBER 3, 2022

Indonesia has granted Emergency Use Authorization (EUA) for the patent-free Covid-19 vaccine, IndoVac, developed by the Texas Children’s Hospital Center for Vaccine Development (CVD) and Baylor College of Medicine, US. PT Bio Farma will manufacture 20 million doses of the vaccine this year.

Vaccination

Vaccination Vaccine Development Production

Moderna leads the development of mRNA vaccines in infectious diseases

Valneva and LimmaTech partner for shigellosis vaccine development

Webinars

Trending Sources

BioNTech targets infectious diseases for vaccine development

Webinars

US launches $5bn effort for new Covid-19 vaccines development

How did pharma develop a vaccine so quickly?

Anivive secures funds to develop human valley fever vaccine

RVAC and University of Pennsylvania to develop mRNA vaccines

WestGene wins FDA approval for mRNA vaccine to treat certain cancers

Merck and Moderna partner to develop and sell cancer vaccine

Evaxion Biotech to develop new vaccines for cancer

Merck stops coronavirus vaccine development in surprise setback

GSK and Flagship Pioneering link for new medicines and vaccines

XtalPi and CK Life Sciences to develop AI-driven tumour vaccine R&D platform

Seattle institute lands $18m funding to develop RNA vaccine for chikungunya

Breaking barriers: Advances and challenges in therapeutic cancer vaccines

Intravacc, Primrose to advance conjugate vaccine development

Sanofi signs mRNA vaccine development deal with IDT Australia

Merck, Pfizer lifted as CDC backs broader use of pneumococcal vaccines

GreenLight and US NIH partner to develop Covid-19 vaccine for variants

LimmaTech secures funding for vaccine technology development

Anixa expands cancer vaccine collaboration with Cleveland Clinic

BioNTech’s RNA vaccine sparks potential in pancreatic cancer

GSK and CureVac restructure mRNA vaccine development deal

SK Bioscience gains UK authorisation for SKYCovion Covid-19 vaccine

Ghana becomes first country to approve Oxford’s malaria vaccine

US FDA makes EUA changes to Pfizer-BioNTech and Moderna Covid-19 vaccines

Evaxion partners with Afrigen Biologics to develop mRNA gonorrhea vaccine

‘Project NextGen’ picks new mRNA, intranasal COVID vaccines for funding

Cancer Research UK and CRIS fund lung cancer vaccine research

Into the unknown: How quickly can vaccines be developed for Disease X

Breakthrough Vaccine Shows High Protection Against Drug-Resistant Superbug in Mice

Brazil’s ANVISA approves Takeda’s dengue vaccine candidate Qdenga

HIV vaccines suffer setbacks but new approaches could turn the tide

IAVI and Biofabri sign deal for TB vaccine candidate development

Novavax gets a lifeline with Sanofi vaccine pact

BioNTech and CEPI partner to develop Mpox vaccine

Intravacc gets NIAID contract for intranasal gonorrhoea vaccine development

UK MHRA approves Takeda’s dengue vaccine Qdenga

India grants approval for Bharat Biotech’s intranasal Covid-19 vaccine

Merck pays $250M to license Moderna cancer vaccine

Novo Nordisk Foundation sets up airborne infection vaccine initiative

China grants EUA to Covid-19 vaccine against XBB descendent lineages

SK bioscience and Hilleman to develop Ebola-Zaire virus vaccine

Indonesia grants EUA for US-developed Covid-19 vaccine

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