Pharmaceutical Technology

APRIL 22, 2024

Discover how PMV Pharmaceuticals Inc's patented compounds restore DNA binding affinity of p53 mutants, aiding in tumor suppression and reducing cancer progression. Explore the specific formula and structural features outlined in the granted patent (Publication Number: US11926632B2).

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DNA 130

Pharmaceutical Technology

APRIL 22, 2024

Detect cancer early with Eurofins' patented method analyzing cell-free DNA for methylated CpGs. Personalized treatment options outlined in recent patent.

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DNA 130

Pharmaceutical Technology

DECEMBER 7, 2023

Synplogen and Ginkgo Bioworks have signed an MOU to expedite DNA manufacturing and gene therapy platform services in Japan.

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DNA Manufacturing Gene Therapy Gene 130

AuroBlog - Aurous Healthcare Clinical Trials blog

NOVEMBER 2, 2022

Scientists have discovered DNA-damaging molecules made by gut bacteria that may help explain why people with inflammatory bowel disease (IBD) have higher rates of colorectal cancer than those without the condition.

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DNA Bacteria Scientist Research 187

Drug Discovery World

JUNE 20, 2024

Join DDW and Thermo Fisher Scientific on 20 June, 11AM EDT/4PM BST, for an exclusive webinar, ‘ Advancing biotherapy manufacturing: innovative strategies for residual DNA and viral titre quantitation using dPCR ’. The post Event today: Discover residual DNA quantitation using digital PCR appeared first on Drug Discovery World (DDW).

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DNA Compliance Manufacturing Production 52

Fierce Pharma

JUNE 3, 2024

subsidiary Bionova Scientific is launching a new business line to provide services around plasmid DNA (pDNA), the companies announced Monday. As part of the pDNA pivot, Bionova is setting up a new facility in The Woodlands, Texas.

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DNA Gene Therapy Contract Manufacturing Gene 105

BioPharma Reporter

JANUARY 24, 2024

We took the time to speak with Amy Walker, vice president at 4basebio, to discuss the merits of synthetic DNA and its future application.

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AuroBlog - Aurous Healthcare Clinical Trials blog

OCTOBER 17, 2022

Studies in mammals have shown that the ‘memories’ of various environmental effects – such as diet, weight, and stress – can be passed on from fathers to offspring, despite these effects not being coded for in the DNA sequences carried by sperm.

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DNA Clinical Trials Clinical Trials Clinical Research 205

Outsourcing Pharma

SEPTEMBER 8, 2023

A benchtop DNA sequencer developed by the U.S. DNA sequencing company Element Biosciences, Inc., has seen sales grow by triple digits and has received more than 100 orders since its launch in March 2022.

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DNA Sales Development Regulation 97

AuroBlog - Aurous Healthcare Clinical Trials blog

NOVEMBER 1, 2023

The Drug Controller General of India (DCGI) has added in-vitro diagnostic (IVD) medical devices including those for diagnosis of Covid-19, ribonucleic acid (RNA) and deoxyribonucleic acid (DNA) extraction kits, among others into the Class C risk category under the Medical Devices Rules (MDR), 2017.

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RNA DNA In-Vitro Drugs 163

Drug Discovery World

NOVEMBER 20, 2023

Raquel Sanches-Kuiper , Vice President of Science and Applications at Evonetix, and Clare Whitewoods , Marketing Communications Manager at Evonetix, look at the benefits synthetic DNA brings to pharmaceutical development.

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DNA Engineer Antibody Gene 69

pharmaphorum

JULY 20, 2022

It has suspected for many years that some diseases may be linked to non-coding or ‘junk’ DNA, but the mechanism behind the pathology hasn’t been worked out. Junk DNA is a term used to describe the 97% of the genetic sequence in human cells found between the 3% coding for our 20,000 genes, once thought to be inert.

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DNA Scientist Genome Genomics 116

Drug Discovery World

JANUARY 23, 2024

” The ability to collect and analyse such a new wealth of ocean data comes from major developments in DNA sequencing technology and computational power. The post World’s largest catalogue of ocean DNA could boost drug discovery appeared first on Drug Discovery World (DDW).

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DNA Drugs Gene Scientist 103

Pharma Times

MAY 10, 2023

Transfer marks start of vital development stage as company expands its range of synthesized DNA

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DNA Development 132

Scienmag

JUNE 26, 2022

The monumental global task to restore degraded ecosystems will need to include sophisticated technologies such as environmental DNA monitoring to understand and support the recovery of complex biospheres, international researchers say.

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DNA Research Engineer 91

Pharma Times

OCTOBER 4, 2022

University of Lincoln and the University of Sheffield are researching how DNA could be repaired

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DNA Research 162

Medical Xpress

NOVEMBER 18, 2022

Rutgers scientists have developed a new approach to stopping viral infections: a so-called live-attenuated, replication-defective DNA virus vaccine that uses a compound known as centanamycin to generate an altered virus for vaccine development.

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DNA Scientist Vaccination Vaccine 91

BioPharma Reporter

JUNE 4, 2024

Bionova Scientific, an Asahi Kasei Group company and full-service biologics CDMO, has announced plans to expand into plasmid DNA (pDNA) production.

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DNA Production Development 52

Pharma Times

NOVEMBER 29, 2022

Bill & Melinda Gates Foundation grant will boost potential of nanoparticle-formulated doggybone DNA

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DNA Vaccination Vaccine 135

Outsourcing Pharma

JULY 18, 2023

company KSQ Therapeutics to co-develop KSQâs lead cancer drug, which is designed to sabotage the DNA repair mechanisms of cancer cells. Roche has entered a licensing and collaboration deal with the U.S.

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DNA Licensing Licensing Drugs 97

Medical Xpress

MAY 14, 2023

For two decades, scientists have been comparing every person's full set of DNA they study to a template that relies mostly on genetic material from one man affectionately known as "the guy from Buffalo."

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DNA Scientist Genome Genomics 98

Medical Xpress

FEBRUARY 22, 2023

Mount Sinai researchers have published a study in Alzheimer's & Dementia: The Journal of the Alzheimer's Association that sheds new light on the role of DNA methylation in Alzheimer's disease (AD).

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DNA Research Protein Gene 98

BioPharma Reporter

FEBRUARY 2, 2023

mRNA pioneer BioNTech has completed construction of its first proprietary plasmid DNA manufacturing facility in Marburg, Germany.

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DNA Manufacturing 112

Scienmag

JULY 19, 2022

Scientists have found that non-coding ‘junk’ DNA, far from being harmless and inert, could potentially contribute to the development of cancer. Their study has shown how non-coding DNA can get in the way of the replication and repair of our genome, potentially allowing mutations to accumulate.

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DNA Genome Genomics Scientist 68

Scienmag

APRIL 7, 2022

Chemists integrated computer functions into rolling DNA-based motors, opening a new realm of possibilities for miniature, molecular robots. Nature Nanotechnology published the development, the first DNA-based motors that combine computational power with the ability to burn fuel and move in an intentional direction.

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DNA Development Engineer 91

Pharmaceutical Technology

APRIL 30, 2024

Unlock the potential of genetic modification with Precision Biosciences Inc's patented MTEM technology for precise editing of eukaryotic cells. Discover how this mitochondria-targeting engineered meganuclease is revolutionizing genetic research.

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Engineer DNA Genetics Research 195

Drug Discovery World

MAY 11, 2023

The first DNA synthesised using Evonetix’s semiconductor chip technology has been delivered to the Department of Chemical Engineering and Biotechnology at the University of Cambridge. The DNA was delivered to Dr Jenny Molloy, Co-chair of the Engineering Biology Interdisciplinary Research Centre at the University of Cambridge.

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DNA Engineer Gene Scientist 52

Pharma Times

AUGUST 16, 2022

Researchers are invited to apply to receive DNA that has been synthesised using Evonetix’s platform

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DNA Research 113

Medical Xpress

FEBRUARY 22, 2023

A new research paper was published in Aging, titled "Metformin use history and genome-wide DNA methylation profile: potential molecular mechanism for aging and longevity."

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DNA Genome Genomics Research 97

Medical Xpress

MAY 16, 2023

Cancer is caused by DNA changes that cause a cell to gradually change from benign to malignant. By studying the types of DNA changes and the consequences of the changes, important insights into the underlying biological processes were obtained. This can lead to metastases in other parts of the body.

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DNA Research 98

Scienmag

NOVEMBER 30, 2021

30, 2021 — A new study led by University of California, Irvine researchers has confirmed a link between altered DNA repair and increased DNA damage associated with spinocerebellar ataxia type 7 (SCA7), a debilitating, sometimes deadly neurodegenerative condition causing movement disorders. Irvine, Calif.,

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DNA Research Medicine 92

Drug Discovery World

MAY 24, 2023

Touchlight, a company providing DNA services and manufacturing enzymes, has completed the redevelopment and expansion of its UK manufacturing facility in London, UK. The expanded facility’s manufacturing capacity has tripled and is now capable of producing more than 8kg a year.

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DNA Gene Editing Gene Therapy Genetics 52

Scienmag

MAY 9, 2022

HOUSTON – (May 9, 2022) – When cells reproduce, the internal mechanisms that copy DNA get it right nearly every time. Rice University bioscientists have uncovered a tiny detail that helps understand how the process could go wrong.

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DNA 86

Scienmag

JUNE 3, 2022

Researchers in Japan have discovered that the local DNA motion inside of human cells remains steady throughout interphase, where the cell grows and replicates its DNA for cell division. The study suggests that this steady-state DNA motion allows cells to conduct housekeeping tasks under similar environments during interphase.

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DNA Research 80

Scienmag

JUNE 3, 2022

Of these various macromolecules that form droplets, DNA is quite interesting because it is predictable and programmable, which are qualities useful in nanotechnology. Recently, the programmability of DNA was used to construct and regulate DNA droplets […].

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DNA Life Science Regulation Research 75

Drug Discovery World

DECEMBER 4, 2023

A novel DNA vaccine in combination with chemotherapy has demonstrated promising clinical results against a deadly form of ovarian cancer. The investigational compound Elenagen is an experimental DNA therapy that consists of a circular piece of DNA called a plasmid that includes a gene for a human protein called p62/SQSTM1.

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DNA Packaging Packaging Vaccination 59

BioPharma Reporter

FEBRUARY 6, 2023

AstraZeneca has cut the cost and time needed to complete DNA synthesis by integrating an assembly framework into Benchling.

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DNA Clinical Development Development 98