Remove DNA Remove Drugs Remove Genome Project
article thumbnail

Genomic projects exploit scale as clinical applications play catch-up

Pharmaceutical Technology

In a Nature publication , Florian Markowetz, PhD, and his fellow researchers analyzed copy number signatures across a number of cancers, and found 17 types of chromosomal instability while identifying 49 new drug targets. Space for discovery, development, and repurposing of drugs. Both teams had the same underlying goal.

article thumbnail

A new dawn of the genomic age: five areas set to be transformed in 2023

pharmaphorum

In March, the collaborative T2T consortium published the first complete telomere-to-telomere sequence of the human genome, filling in the last 8% of the 3 billion base pairs that make up our DNA. Understanding individual drug reactions and metabolism Pharmacogenomics is emerging as an important area.

Genomics 129
Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

article thumbnail

The future of genomic medicine: can it fulfil its promises?

pharmaphorum

Here he gives us a deeper look at how genomic medicine is evolving and the barriers that are preventing it from reaching its full potential. Now, however, the field is changing with respect to genomic medicine. On one hand, unfortunately this means that many drugs are doomed to failure. This allows for much lengthier reads.

Genomics 119
article thumbnail

A history of blood cancer treatment

pharmaphorum

Just over a decade after it was developed by biochemist Nicholas Lyndon, Imatinib received US Food and Drug Administration (FDA) approval in 2001. 2012 – The 100,000 Genomics Project begins. Unlocking the secrets of the human genome has intrigued investigators for centuries. 2002 – Emergence of CAR-T therapy.

article thumbnail

CRISPR therapies targeting the next breakthrough in oncology

pharmaphorum

In 2012, Jennifer Doudna and Emmanuelle Charpentier published a paper in Science where they outlined isolating the components of the CRISPR-Cas9 system and demonstrated how it could be used to cut specific sites in isolated DNA. The publication and their work eventually led to the pair being awarded the Nobel Prize in Chemistry in 2020.

article thumbnail

Spatial Genomics, Transcriptomics and Proteomics Solutions – An Amelioration of Tissue Analytics

Roots Analysis

As a result, industry and non-industry stakeholders, are on the lookout for advanced platforms that can simultaneously capture the arrangement of multiple biomolecules (DNA, RNA, proteins and others) with single-cell or subcellular resolution. For more details on this emerging domain, check out the following report : SPATIAL GENOMICS MARKET.

article thumbnail

Bioinformatics Jobs: How to Succeed in This Competitive Space

XTalks

The Human Genome Project could not have succeeded without the use of bioinformatics. Since the conclusion of the project in 2003, bioinformatics tools have been used to identify genes and elucidate their function with the aim of developing gene-based strategies for disease prevention, diagnosis and treatment.