DNA, Genetic Disease, Research and RNA - Clinical Research Informer

Turning science into business: Amplifying mRNA by targeting regRNAs

Drug Discovery World

APRIL 17, 2024

DDW’s Diana Spencer speaks to Josh Mandel-Brehm , CEO of Massachusetts-based biotech CAMP4, to understand the role regulatory RNAs play in gene expression and how the founders overcame the challenge of launching a business based on brand new science. DS: How easy was it to transfer theoretical research into a viable business?

Gene Expression

Gene Expression Gene Genetic Disease RNA

Moderna partners with Life Edit for mRNA gene editing therapies

Pharmaceutical Technology

FEBRUARY 23, 2023

Moderna has entered a strategic research and development partnership with ElevateBio’s Life Edit Therapeutics to discover and develop new in-vivo mRNA gene editing therapies. Under the deal, both companies will partner on the research and preclinical studies, which will be funded by Moderna.

Gene Editing

Gene Editing Gene In-Vivo Gene Therapy

Gene Therapy and Pharmacokinetics

Camargo

JULY 27, 2021

It is a comprehensive term which encompasses a large variety of therapy products including viral and bacterial vectors, plasmid DNA, human gene editing technology, and patient-specific cellular gene therapy. For example, it is beneficial to administer RNA treatments for some lung diseases directly to the disease site through inhalation.

Gene Therapy

Gene Therapy Gene Gene Editing Genetics

Next Generation Sequencing (NGS) Library Preparation Kits Market: Current Scenario and Future Potential

Roots Analysis

FEBRUARY 21, 2022

Advancement in DNA sequencing technologies have resulted in noteworthy developments in various healthcare-related research fields, such as diagnostics and personalized medicine. During our research, we came across more than 55 players, which claim to offer 280+ NGS library preparation kits. Concluding Remarks.

Marketing

Marketing Gene Sequencing DNA Genome

Why genomic healthcare data matters in the development of new therapies

Drug Discovery World

NOVEMBER 7, 2022

One might argue that this all started getting exciting with the launch of the Human Genome Project, which the National Human Genome Research Institute consider to be one of the greatest scientific feats in history 1. With Revio, researchers will be able to access that same great chemistry, but at a much larger scale.” . The origins

Genome

Genome Genomics Development Genetics

The evolution of the RNA therapeutics landscape

Drug Discovery World

JULY 8, 2024

Beard Distinguished Professor of Experimental Surgery and the Founding Director of the Translational Research Institute at Duke University, explores the rise of RNA therapeutics. With high-throughput RNA sequencing, it is evident the majority of RNAs in human cells are not actually messengers.

RNA

RNA Protein Gene Expression Vaccination

The future outlook for mRNA therapies

Drug Discovery World

APRIL 30, 2024

Messenger RNA (mRNA) has come into focus within the drug discovery and development as an exciting tool to deliver genetic information. Yochi Slonim, CEO of Anima explains further: “The impact of the Covid-19 pandemic on mRNA research has been significant, fundamentally altering the landscape of therapeutics.

RNA

RNA Protein Vaccination Vaccine

Key Trends in the Life Sciences to Look Forward to in 2022

XTalks

DECEMBER 22, 2021

The RNA Revolution: From mRNA Vaccines to RNA Editing. The age of RNA is officially here, and it’s here to stay as more than a passing life science trend. percent, according to a report by BCC Research. RNA technology is not new nor has its potential been surprising. RNA in the Making. RNA Therapeutics.

Life Science

Life Science RNA Vaccination Vaccine

Top 10 Fastest Growing Biotech Companies in 2023

XTalks

DECEMBER 13, 2023

In 2023, biotechnology and pharmaceutical companies leverage cutting-edge technology and significant investments in research and development (R&D) to continue pushing the boundaries of innovation in the healthcare sector, transcending the challenges posed by the pandemic. In the third quarter of 2023, the company’s revenue surged to $63.7

Genetics

Genetics Vaccination Vaccine DNA

Epigenetic Editing with CRISPR Might Be Easier Than We Thought

XTalks

MAY 4, 2021

Researchers at the University of California San Francisco (UCSF) and the Whitehead Institute have developed a novel CRISPR-based tool called “CRISPRoff” that can switch off genes in human cells through epigenetic editing without altering the genetic sequence itself. The research was published earlier this month in the journal Cell.

DNA

DNA Gene Gene Silencing Genome

Generating Over a Billion Cells with CRISPR for Next Generation Cell Therapies

XTalks

AUGUST 29, 2022

This technology has powerful implications for therapeutic uses, such as replacing mutated or disease-causing genes or increasing the activity of cancer-fighting cells. Viral vectors have traditionally been used in gene editing where the shells of viruses carry the template DNA into cells, but this method has its disadvantages.

Gene Editing

Gene Editing DNA Gene Genome

Using CRISPR to Edit the Epigenome Might Be Easier Than We Thought

XTalks

MAY 4, 2021

Researchers at the University of California San Francisco (UCSF) and the Whitehead Institute have developed a novel CRISPR-based tool called “CRISPRoff” that can switch off genes in human cells without editing the genetic sequence itself. These modifications regulate gene expression without altering the sequence or structure of DNA.

DNA

DNA Gene Gene Silencing Genome

Unlocking the potential of mRNA for the future treatment of rare diseases

Drug Discovery World

FEBRUARY 28, 2023

Moderna Therapeutics, a biotechnology company that has developed SARS-CoV-2 mRNA vaccines, has at least six rare disease programmes currently in preclinical and clinical development (Table 1). At this stage, qPCR can be used to check for IVT efficiency, residual DNA contamination and adventitious agents such as microbes.

Genetics

Genetics Genetic Analysis Vaccination Vaccine

Covid-19 vaccine success bolsters nanoparticle drug delivery research

Pharmaceutical Technology

APRIL 24, 2023

Robert Langer was part of the first cohort of researchers to begin nanoparticle research , as his lab at Cornell University developed tiny particles to deliver large molecules for angiogenesis. The next wave came from early research into liposomes and lipid nanoparticles, both of which are used for drug delivery.

Drug Delivery

Drug Delivery Vaccination Vaccine Research

Clinical Research Informer

Turning science into business: Amplifying mRNA by targeting regRNAs

Moderna partners with Life Edit for mRNA gene editing therapies

Trending Sources

Gene Therapy and Pharmacokinetics

Next Generation Sequencing (NGS) Library Preparation Kits Market: Current Scenario and Future Potential

Why genomic healthcare data matters in the development of new therapies

The evolution of the RNA therapeutics landscape

The future outlook for mRNA therapies

Key Trends in the Life Sciences to Look Forward to in 2022

Top 10 Fastest Growing Biotech Companies in 2023

Epigenetic Editing with CRISPR Might Be Easier Than We Thought

Generating Over a Billion Cells with CRISPR for Next Generation Cell Therapies

Using CRISPR to Edit the Epigenome Might Be Easier Than We Thought

Unlocking the potential of mRNA for the future treatment of rare diseases

Covid-19 vaccine success bolsters nanoparticle drug delivery research

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