pharmaphorum

MAY 7, 2021

Founded by Nobel prize winner Emmanuelle Charpentier, CRISPR Therapeutics has been at the forefront of the gene editing technology and has refined it to the point where it can be used to accurately edit DNA to correct genetic conditions or modify cells to fight disease.

Gene Editing 52

Gene Editing Gene Genetic Engineering DNA 52

The Pharma Data

JANUARY 4, 2021

Improper disposal of antibiotics also releases these drugs into the environment, and researchers working with these drugs in the lab also have concern over their ultimate effects on study results. The process described in the research was previously developed by a former graduate student research in O’Malley’s lab, Justin Yoo.

Bacteria 52

Bacteria Engineer Genetics Genetic Engineering 52

NY Times

FEBRUARY 22, 2021

Two patients in a gene therapy study developed cancer years after treatment. It is not clear whether the therapy was responsible.

Gene Therapy 54

Gene Therapy Trials Research Gene 54

Drug Discovery World

FEBRUARY 14, 2024

The researchers suggested that if this tool had been deployed at the start of the pandemic, it would have accurately identified which variants of SARS-CoV-2 had the highest escape potential. However, such achievements can only be achieved by leveraging research strengths, regulatory capabilities and technical platforms.

Protein 59

Protein Vaccination Vaccine Manufacturing 59

Drug Discovery World

JUNE 27, 2024

SeekRNA’s ability to target selection with precision and flexibility sets the stage for a new era of genetic engineering, surpassing the limitations of current technologies,” Dr Ataide said. Dr Ataide added: “SeekRNA can precisely cleave the target site and insert the new DNA sequence without the use of any other proteins.

Gene Editing 59

Gene Editing Gene DNA Genetic Engineering 59

Drug Discovery World

MAY 7, 2024

AEX chromatography has primarily been used in the polishing AEX step for the removal of impurities, such as DNA, HCP, etc., DC: We’ve seen in the last decade or so a lot of research and interest in the use of single-use technologies. as well as viral reduction and other product-related impurities.

Antibody 59

Antibody Production Manufacturing Engineer 59

Advarra

JUNE 12, 2023

Gene therapy research is exciting and full of promise, but because of the risks involved, it’s also highly regulated, requiring an institutional biosafety committee (IBC) to provide additional oversight and risk assessment. IRBs are tasked with protecting research subject’s rights and welfare. How are IBCs Different from IRBs?

Genetic Engineering 98

Genetic Engineering Gene Therapy Genetics Engineer 98

Pharmaceutical Technology

FEBRUARY 15, 2023

Within the emerging innovation stage, cell therapy for ocular disorders, coronavirus vaccine components, and DNA polymerase compositions are disruptive technologies that are in the early stages of application and should be tracked closely. Nucleases are enzymes that hydrolytically cleave the phosphodiester backbone of DNA.

Gene Splicing 130

Gene Splicing Gene Recombinant DNA Technology DNA 130

Pharmaceutical Technology

JUNE 4, 2023

Within the emerging innovation stage, cell therapy for ocular disorders, coronavirus vaccine components, and DNA polymerase compositions are disruptive technologies that are in the early stages of application and should be tracked closely. Transcription of the cap gene is initiated from a single promoter termed p40.

Gene 262

Gene Gene Therapy Genetics DNA 262

Drug Discovery World

NOVEMBER 17, 2022

The rapidly growing area of synthetic biology – including molecular biology, biotechnology, biophysics, and genetic engineering – is having a marked impact on the drug discovery landscape. The researchers duly fed its relevant sequences into an algorithm, which proposed a handful of compounds that cil likely produces.

Bacteria 52

Bacteria Engineer Gene Genetics 52

Drug Discovery World

JULY 9, 2024

Harnessing the power of sophisticated GEMs and humanized mice is essential to moving research forward. Among these models, research mice and rats stand out as invaluable resources, facilitating the understanding of disease mechanisms and the development of novel drugs.

In-Vivo 59

In-Vivo Genetic Engineering Genetics Drugs 59

Roots Analysis

AUGUST 31, 2023

Gene switches can be regulatory proteins or specific DNA sequences that act to either switch on or off the expression of a gene. Basic Components of Gene Switch Gene switches are composed of noncoding DNA sequences and transcription factors.

Gene 40

Gene Gene Therapy Gene Expression Regulation 40

Roots Analysis

MARCH 16, 2023

Messenger ribonucleic acid (mRNA) is a single-stranded molecule that is complementary to a gene’s DNA. It is important in the process of protein synthesis because mRNA is responsible for transferring genetic information from DNA to ribosomes, which then decodes the genetic information into a protein.

Vaccination 52

Vaccination Vaccine DNA Protein 52

pharmaphorum

SEPTEMBER 13, 2022

In fact, according to Blood Cancer UK research, more than half of UK adults cannot name a single symptom of blood cancer. . Over the past two centuries, researchers have identified more than 100 different types of blood cancer, while most patients may be familiar with the big three (leukaemia, lymphoma, and melanoma).

Genome Project 85

Genome Project Genome Genomics DNA 85

Drug Discovery World

JULY 5, 2024

Beyond CRISPR: New mechanism for genetic programming discovered A team of researchers have discovered the bridge recombinase mechanism, a precise and powerful tool to recombine and rearrange DNA in a programmable way.

Gene Therapy 59

Gene Therapy Gene Editing In-Vivo Gene 59

Roots Analysis

FEBRUARY 13, 2023

It transfers genetic information form to DNA to ribosomes, a specialized structure, or organelle, which decodes genetic information into a protein. With the help of genetic engineering, synthetic mRNAs can express proteins, as they structurally resemble a natural mRNA.

Manufacturing 52

Manufacturing Drug Delivery Systems Genetic Engineering RNA 52

Roots Analysis

FEBRUARY 15, 2022

Presently, there are several companies and universities, which are exploring the potential of different gene editing technologies beyond CRISPR for basic research, and the development of gene editing solutions. Genome Editing is a way of making changes in the DNA. These technologies act as scissors, cutting the DNA at specific spots.

Genome 52

Genome Genomics Gene Editing DNA 52

Advarra

AUGUST 10, 2023

Rapid growth in gene therapy is expected to receive additional support as the Food and Drug Administration (FDA) Center for Biologics Evaluation and Research (CBER) prepares to launch Operation Warp Speed for Rare Diseases. How Can Research Professionals Mitigate Risks with Engineered Genetic Materials?

Gene Therapy 52

Gene Therapy Development Gene Drugs 52

Drug Discovery World

JANUARY 23, 2023

Kevin Hemphill, R&D Manager at PerkinElmer’s Horizon Discovery explores how base editing has emerged as an attractive gene editing option for researchers wanting to develop stem cell-based therapies.

Gene Editing 52

Gene Editing Gene Engineer DNA 52

Drug Discovery World

NOVEMBER 9, 2023

Novel platforms This session will begin with chariperson’s remarks from Lars Linden, PhD, Vice President, Head, Biologics Research, Bayer HealthCare, which will be followed by a keynote presentation by Agnieszka Kielczewska, PhD, Director, Research, Antibody Discovery and Screening, Biologics Discovery, Amgen.

Engineer 52

Engineer Antibody Protein In-Vivo 52

Roots Analysis

OCTOBER 22, 2023

In the last few years, researchers have become interested in using in vitro transcribed (IVT) mRNA as a drug delivery agent. In the last few years, researchers have become interested in using in vitro transcribed (IVT) mRNA as a drug delivery agent. Ronit holds a B.

RNA 40

RNA Protein Genetics Gene Expression 40