Pharmaceutical Technology

SEPTEMBER 23, 2024

s groundbreaking patent for synthesizing specific DNA sequences. Learn how their innovative method enhances genetic engineering and biotechnology. Discover Telesis Bio Inc.'s

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DNA Genetic Engineering Engineer Genetics 130

Bio Pharma Dive

FEBRUARY 15, 2024

The partnership will use Intellia's "DNA writing” technology, and initially focus on people with the lung disease who have limited or no available treatment options.

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Genetics Medicine DNA 184

Pharma Mirror

FEBRUARY 23, 2021

The post Catalent to Acquire Delphi Genetics and Launch US Plasmid Manufacturing Site appeared first on Pharma Mirror Magazine. SOMERSET, N.J. Catalent is also announcing the launch of pDNA development and manufacturing services at its Rockville, Maryland facility. Together, the addition of pDNA technology and production capabilities.

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Medical Xpress

APRIL 28, 2023

A team of researchers at the Broad Institute of MIT and Harvard has developed a new approach to next-generation sequencing that detects genetic mutations within single molecules of DNA.

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DNA Genetics Development Research 87

Pharma Times

APRIL 22, 2022

Researchers were able to detect specific combinations of genetic alterations which may hold key to the growth of cancers

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DNA Genetics Research 153

STAT News

FEBRUARY 16, 2023

Zhang, one of the leading scientists in the groundbreaking field of genetic editing, had reached out two days prior to discuss a new company he was working on. billion combined.

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Genetics DNA Genomics Genome 142

Scienmag

APRIL 15, 2021

Team of Japanese and European scientists identify a novel genetic mitochondrial disorder by analyzing DNA samples from three distinct families Credit: Fujita Health University DNA ligase proteins, which facilitate the formation of bonds between separate strands of DNA, play critical roles in the replication and maintenance of DNA.

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Genetics DNA Genomics Genome 105

STAT News

SEPTEMBER 16, 2022

Intellia Therapeutics said Friday the first six patients to receive its CRISPR-based treatment for a genetic swelling disorder have safely had small, corrective changes made to dysfunctional DNA inside their liver cells.

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DNA Gene Editing In-Vivo Genetics 142

Pharmaceutical Technology

MARCH 24, 2023

Moderna has entered a strategic partnership with Generation Bio for the development of non-viral genetic medicines. Moderna’s biological and technical expertise will be combined with core technologies of the non-viral genetic medicine platform from Generation Bio.

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Genetics Medicine Development In-Vivo 130

Medical Xpress

MAY 14, 2023

For two decades, scientists have been comparing every person's full set of DNA they study to a template that relies mostly on genetic material from one man affectionately known as "the guy from Buffalo."

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DNA Scientist Genome Genomics 98

STAT News

JANUARY 10, 2023

Illumina, the largest maker of DNA sequencing technology, told investors exactly what they didn’t want to hear on Monday. For years, Illumina shares rose steadily as the company led the way on pushing down the costs involved in doing genetic research.

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Medical Xpress

MAY 8, 2023

Scientists at the National Institutes of Health have identified new genetic risk factors for two types of non-Alzheimer's dementia. These findings were published in Cell Genomics and detail how researchers identified large-scale DNA changes, known as structural variants, by analyzing thousands of DNA samples.

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Genetics DNA Research Genomics 98

Scienmag

NOVEMBER 16, 2020

Goodsell and RCSB PDB Darwin’s theory of evolution should be expanded to include consideration of a DNA stability “energy code” – so-called “molecular Darwinism” – to further account for the long-term survival of species’ characteristics on Earth, according to Rutgers […].

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DNA Genetics Gene Medicine 97

Worldwide Clinical Trials

DECEMBER 12, 2022

Genetic testing provides patients with a diagnosis for their illness, helps patients and family members to understand risks of developing new diseases, and can be used to support clinical trial advancement. What are the benefits and limitations to using genetic testing? It is important to consider the type of testing performed (e.g.,

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Clinical Trials Clinical Trials Genetics Trials 130

Scienmag

NOVEMBER 2, 2021

In every advanced organism, the molecule called DNA (deoxyribonucleic acid, to use its full name) forms the genetic code.

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DNA Genetics Scientist Engineer 88

Pharma Times

APRIL 14, 2023

Product delivers epigenetic information from a single low-input DNA library without medical treatment

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Genetics DNA Production 123

STAT News

SEPTEMBER 30, 2022

SAN DIEGO — After a steep drop in its stock price and with mounting competition from rivals, genomics giant Illumina on Thursday launched a new line of high-powered DNA sequencers, ratcheting up the race to read genetic information accurately and cheaply. Continue to STAT+ to read the full story…

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DNA Genomics Genome Genetics 105

Medical Xpress

MAY 15, 2023

The traces of genetic material that humans constantly shed wherever they go could soon be used to track individual people, or even whole ethnic groups, scientists said on Monday, warning of a looming "ethical quagmire".

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Scientist DNA Genetics 133

Worldwide Clinical Trials

JUNE 13, 2024

This groundbreaking approach can help tailor medical treatments to an individual’s genetic makeup, considerably enhancing drug efficacy and safety while minimizing adverse drug reactions. These results are largely due to the higher cell density in blood, which includes DNA-rich white blood cells. for buccal swabs and 93.2%

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Medicine DNA Compliance Clinical Trials 182

XTalks

MAY 23, 2024

One of the more intriguing developments in cancer research in recent years is the growing understanding of clonal hematopoiesis, a phenomenon where blood cells expand from a single clone due to genetic mutations. Clonal hematopoiesis increases in prevalence with age and can precede hematologic malignancies.

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Genetics Research Genome Genomics 114

pharmaphorum

AUGUST 23, 2021

The COVID-19 pandemic accelerated the development of mRNA-based vaccines, and its influence has now extended to DNA-based shots as well, with Zydus Cadila’s ZyCoV-D getting emergency use authorisation in India. Proponents of the approach claim that DNA vaccines may have advantages over other technologies like mRNA.

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DNA Vaccine Vaccination Genetic Engineering 98

XTalks

DECEMBER 14, 2022

Developed by MIT researchers Jonathan Gootenberg and Omar Abudayyeh, PASTE (Programmable Addition via Site-specific Targeting Elements) gene editing technology can insert genes as long as 36,000 DNA base pairs to liver cells in mice as well as several types of human cells.

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Gene Editing DNA Gene Gene Sequencing 98

Medical Xpress

NOVEMBER 30, 2022

Like the New York City subway system, the DNA in our cells needs to operate around the clock—and it's in constant need of repair.

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Genetics Genetic Disease DNA Research 97

Scienmag

JUNE 16, 2022

In 2014, Professor Anton Henssen discovered something unusual in the cells of pediatric cancer patients: small rings of DNA, which meant that part of the genetic information was no longer packaged in the chromosomes as normal.

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DNA Packaging Packaging Genomics 83

Scienmag

JANUARY 8, 2021

Dill/NIST In a technique known as DNA origami, researchers fold long strands of DNA over and over again to construct a variety of tiny 3D structures, including miniature biosensors and drug-delivery containers.

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DNA Drug Delivery Containment Research 95

Scienmag

JUNE 16, 2022

Thirteen genetic variants associated with disease in cats are present in more pedigreed breeds than previously thought, according to the largest ever DNA-based study of domestic cats, led by Heidi Anderson from Wisdom Panel in the United States and colleagues from the University of Helsinki in Finland.

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DNA Genetics 87

Pharmaceutical Technology

DECEMBER 8, 2022

Developing neoantigen products needed for the therapy has faced difficulties including lead time to get GMP DNA and complicated supply chains. Touchlight CEO Karen Fallen said: “Innovation in enzymatic DNA manufacturing is enabling advancements such as Odimma’s immunotherapy programme to deliver treatments to critically ill patients.

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DNA Genetics Manufacturing Production 147

STAT News

SEPTEMBER 20, 2022

A new CRISPR startup — backed by some big names in venture capital — is planning to develop gene-editing treatments that can insert a genetic sequence of any length, at any location in the DNA strand, according to industry insiders and documents.

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DNA Gene Editing Genomics Genome 98

Medical Xpress

NOVEMBER 30, 2022

In our cells, the language of DNA is written, making each of us unique. A tandem repeat occurs in DNA when a pattern of one or more nucleotides—the basic structural unit of DNA coded in the base of chemicals cytosine (C), adenine (A), guanine (G) and thymine (T)—is repeated multiple times in tandem.

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Genetics DNA Scientist 98

STAT News

NOVEMBER 30, 2022

Using old hamster cages, chair cushions purchased from Kmart, and a Polaroid camera given to Tanzi for his 11th birthday, they began taking pictures of pieces of DNA carrying the genetic code of each member of that family.

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Genetics Scientist DNA Gene 111

STAT News

MARCH 29, 2023

Twenty years ago, virtually all people seeking genetic testing were individuals diagnosed with diseases possibly linked to their genetic makeup. Today, millions of people order genetic tests to learn about their ancestry, as well as to understand what their genes say about their future health. The opportunity?

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DNA Genetics Gene 105

XTalks

JULY 19, 2021

Phosphorus, a leading preventative genomics company, has developed the first comprehensive preventative genetic test for consumers. The test is called GeneCompass and features medical-grade technology to provide a holistic assessment of genetic health and wellness. The Phosphorus GeneCompass test has a list price of $249.

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Genetics Genome Genomics Gene 98

Worldwide Clinical Trials

NOVEMBER 12, 2024

CGTs address rare and complex diseases at the root cause with increasing use in cancer, genetic disorders, and autoimmune diseases. Cell therapy, specifically, is changing our narrative around chronic and lethal conditions.

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Gene Therapy Clinical Supply Trials Gene 182

Scienmag

MAY 3, 2021

Detection innovation could enhance drug development and cancer research Credit: Richard Hooley/UCR Small changes in the structure of DNA have been implicated in breast cancer and other diseases, but they’ve been extremely difficult to detect — until now.

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DNA Development Drugs Research 98

Scienmag

JULY 12, 2021

USC researchers have achieved a better way to identify elusive DNA variants responsible for genetic changes affecting cell functions and diseases. Using computational biology tools, scientists at the university’s Dornsife College of Letters, Arts and Sciences studied “variable-number tandem repeats” (VNTR) in DNA.

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DNA Research Genetics Scientist 69

Scienmag

DECEMBER 28, 2021

Each one of the trillions of cells that make up the human body suffers more than 10,000 DNA lesions every day. These injuries would be catastrophic if cells were unable to repair them, but a very delicate machinery that detects and repair genetic damage is at work to prevent DNA mutations and diseases such as […].

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DNA Scientist Development Genetics 76

Scienmag

DECEMBER 7, 2020

By pairing an iPhone with a handheld DNA sequencer, users can create a mobile genetics laboratory, reminiscent of the “tricorder” featured in Star Trek. Credit: CSHL Cold Spring Harbor Laboratory (CSHL) scientists developed the world’s first mobile genome sequence analyzer, a new iPhone app called iGenomics.

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