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The group analysed 12,222 samples collected through whole genome sequencing efforts of the UK National Health Service as part of the 100,000 GenomesProject and added further data on 6,418 cancers from the International Cancer Genome Consortium and the Hartwig Medical Foundation. Both teams had the same underlying goal.
The following year, the regulator also approved Rituximab, a monoclonal antibody targeting CD-20 positive B-cells, as a companion treatment of chemotherapy in older diffuse large B-cell lymphoma patients. 2012 – The 100,000 GenomicsProject begins. This was an entirely new approach to DNA research.
Here he gives us a deeper look at how genomic medicine is evolving and the barriers that are preventing it from reaching its full potential. Unsurprisingly, in many respects, the human genome turned out to be a lot more complex than was originally thought. This allows for much lengthier reads.
The Human GenomeProject could not have succeeded without the use of bioinformatics. Since the conclusion of the project in 2003, bioinformatics tools have been used to identify genes and elucidate their function with the aim of developing gene-based strategies for disease prevention, diagnosis and treatment.
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