XTalks

MAY 12, 2021

In this episode, Ayesha discusses a new tool that uses CRISPR to modulate gene expression without editing DNA sequences. The team debates the ethical considerations around epigenetic therapies and genome editing, and how scientific communications should be improved to help educate the public on complex medical breakthrough.

Life Science 52

Life Science Gene Expression Gene DNA 52

XTalks

APRIL 29, 2021

However, the variant viral genomes will still persist in the latent reservoir as provirus and can be detected with proviral DNA testing. In contrast to HIV RNA, HIV proviral DNA remains present in a patient’s cells even during virological suppression. Proviral DNA Genotyping. HIV Drug Resistance Testing.

DNA 98

DNA Drugs RNA Genotype 98

The Pharma Data

JANUARY 31, 2021

NASDAQ: ILMN), the global leader in DNA sequencing and array-based technologies, and Sequoia Capital China , a leading investment firm, today announced a collaboration to catalyze the startup ecosystem in China with the launch of the Sequoia Capital China Intelligent Healthcare Genomics Incubator, Powered by Illumina.

Genome 52

Genome Genomics Life Science DNA 52

Drug Discovery World

MAY 5, 2023

Eterna Therapeutics, a life science company focused on mRNA cell engineering, has acquired Exacis Biotherapeutics’ immuno-oncology platform. In contrast to DNA-based reprogramming and gene editing, the mRNA-based approach does not expose cells to expensive and potentially harmful viruses or DNA vectors.

Gene Editing 52

Gene Editing Engineer DNA Life Science 52

Drug Discovery World

MAY 25, 2023

Several new products for the life sciences sector have been launched over the last month, from miniature semiconductor chip (MSC) technology to a new inhalation testing service. DDW provides an update.

Production 52

Production Reagent DNA Drugs 52

Drug Discovery World

FEBRUARY 8, 2024

In 2023, DDW hosted a webinar, ‘A comprehensive guide to using adeno-associated virus (AAV) vectors in gene therapy’, supported by Azenta Life Sciences. Questions were fielded from the audience, which included: What analysis will be performed to evaluate host or other DNA contamination? Why are those important?

Gene Therapy 59

Gene Therapy Gene Bioinformatics Life Science 59

Drug Discovery World

OCTOBER 3, 2023

Earlier this year, DDW hosted a webinar, ‘A comprehensive guide to using adeno-associated virus (AAV) vectors in gene therapy’, supported by Azenta Life Sciences. Questions were fielded from the audience, which included: What analysis will be performed to evaluate host or other DNA contamination?

Gene Therapy 52

Gene Therapy Gene Life Science Bioinformatics 52

XTalks

DECEMBER 20, 2023

As we step into 2024, the life sciences continue to evolve at an unprecedented pace, driven by technological innovation, a deeper understanding of human biology and the application of new technologies in areas like drug development and health wearables. These companies are at various stages of research and clinical trials.

Life Science 119

Life Science Gene Editing Development Clinical Trials 119

The Pharma Data

JANUARY 5, 2021

Genomic surveillance is essential in fighting the pandemic. Illumina is pleased to partner with the CDC and Helix to provide accurate sequencing that can contribute to rapidly scaling genomic surveillance in the US to better understand the presence of B.1.1.7 variant in 4 samples from California and Florida. About Helix.

Genome 52

Genome Genomics Life Science Development 52

XTalks

JUNE 16, 2023

. “Companion diagnostics are high-quality, well-validated genomic tests that provide critical information to help oncologists make informed treatment decisions for their patients,” said Mia Levy, MD, PhD, chief medical officer at Foundation Medicine. ” What is FoundationOne Liquid CDx?

FDA Approval 97

FDA Approval Genome Genomics DNA 97

Drug Discovery World

JANUARY 30, 2023

DDW Editor Reece Armstrong takes a look at Lithuania’s life sciences sector and what it means for start-ups operating in the country. Despite consisting of largely small enterprises, Lithuania is still home to some large players in the life sciences sector including Thermo Fisher Scientific, Teva and Northway Biotech.

Life Science 98

Life Science Genome Genomics Development 98

Drug Discovery World

JUNE 5, 2023

The panel was moderated by Alexander Nuyken, Head Life Sciences Markets Europe, Middle East & Africa, JLL. I consider one of my responsibilities to advocate the advent of a new era for 3D genomics. Our final goal is to pioneer the 3D genomic field and demonstrate the impact on precision medicine.

Genome 52

Genome Genomics Life Science Genetics 52

Drug Discovery World

OCTOBER 16, 2023

Maina Bhaman, Partner at Sofinnova Partners, says: “The UK is an attractive space for drug discovery companies and a prime environment for investment due to its talent, infrastructure, and genomics research. CellProthera also appointed the Newcastle Centre for Life’s GMP cell therapy centre to produce the ATMP.”

Drugs 75

Drugs Life Science Gene Therapy Genome 75

Pharmaceutical Technology

MAY 8, 2023

Within the emerging innovation stage, cell therapy for ocular disorders, coronavirus vaccine components, and DNA polymerase compositions are disruptive technologies that are in the early stages of application and should be tracked closely.

Genetics 130

Genetics DNA Genetic Engineering Antibody 130

Pharmaceutical Technology

FEBRUARY 3, 2023

The field of genomic medicine has reached a true turning point. The established method for this process is a triple transfection using three different DNA plasmids. More efficient, suspension-based cell culture processes are urgently needed in the now fast-developing genomic medicine space.

Genome 244

Genome Genomics Medicine Gene Therapy 244

Drug Discovery World

FEBRUARY 13, 2023

What is important is how we use it, and SLAS2023 is taking the necessary next steps through a diverse range of talks and presentations, which ask: How has life sciences technology pushed innovation to boost the drug discovery process? Nobody would suggest that there is not enough data.

Genome 52

Genome Genomics Life Science Drugs 52

Drug Discovery World

JULY 11, 2023

Tim Lowery , President, JSR Life Sciences, asks whether artificial intelligence can do for life sciences what it has done in other sectors and whether these tools can keep up with the complexities of human biology. So, where do we go from here to realise their potential in life sciences?

Big Data 40

Big Data Development Life Science Drugs 40

The Pharma Data

OCTOBER 19, 2020

20, 2020 /PRNewswire/ — Caris Life Sciences® , a leading innovator in molecular science focused on fulfilling the promise of precision medicine, announced today that Winship Cancer Institute of Emory University (Winship) has joined Caris’ Precision Oncology Alliance (The Alliance/POA). .”

Life Science 52

Life Science Clinical Trials Clinical Trials RNA 52

pharmaphorum

DECEMBER 9, 2022

Canada’s Varient , developing a rare disease patient community-sourced patient-reported outcome (PRO) and RWE platform. PharmStars is accepting applications until 14 January 14 for its next cohort in spring 2023, on the theme of innovations in women’s health and health equity.

Life Science 52

Life Science DNA Genome Genomics 52

XTalks

SEPTEMBER 9, 2021

It was found that the gene being delivered through the therapy had integrated into the genomes of six of the seven mice that were administered the highest dose. Although a rare event that occurs at very low frequency, AAV vectors can integrate into genomes through homologous recombination.

Gene Therapy 105

Gene Therapy Gene Genome Genomics 105

Pharmaceutical Technology

MAY 8, 2023

Within the emerging innovation stage, cell therapy for ocular disorders, coronavirus vaccine components, and DNA polymerase compositions are disruptive technologies that are in the early stages of application and should be tracked closely.

Antibody 147

Antibody Vaccination Vaccine Dermatology 147

XTalks

DECEMBER 14, 2022

Developed by MIT researchers Jonathan Gootenberg and Omar Abudayyeh, PASTE (Programmable Addition via Site-specific Targeting Elements) gene editing technology can insert genes as long as 36,000 DNA base pairs to liver cells in mice as well as several types of human cells.

Gene Editing 98

Gene Editing DNA Gene Gene Sequencing 98

The Pharma Data

DECEMBER 22, 2020

and European Union, this presents a compelling option to patients, their families, and medical professionals to minimize the diagnostic odyssey often faced in clinical genetic testing settings,” said Kevin Meldrum, general manager and vice president of Agilent’s Genomics Solutions Division. About Agilent Technologies.

Genome 40

Genome Genomics Genetics In-Vitro 40

XTalks

NOVEMBER 30, 2023

The noteworthy candidate, EBT-101, is designed to eliminate HIV proviral DNA using CRISPR-Cas9 along with two guide RNAs (gRNAs). These dual gRNAs target three specific sites within the HIV genome, facilitating the removal of substantial portions of the viral DNA and minimizing the potential for viral escape.

FDA Approval 111

FDA Approval Gene Therapy Clinical Trials Clinical Trials 111

XTalks

MAY 10, 2022

Somatic variant classification and interpretation are the most time-consuming steps of tumor genomic profiling,” said the co-author of the study Marilyn M. Li, MD, Professor of Pathology and Laboratory Medicine, Director of Cancer Genomic Diagnostics. CancerVar provides a powerful tool that automates these two critical steps.

Bioinformatics 98

Bioinformatics Development Gene Genome 98

XTalks

APRIL 5, 2021

Bioinformatics jobs are commonly found in the fields of computer information science, pharmaceuticals, biotechnology, medical technology, computational biology, proteomics and medical informatics. The Human Genome Project could not have succeeded without the use of bioinformatics. How to Become a Bioinformatics Analyst.

Bioinformatics 59

Bioinformatics Engineer Scientist Genome 59

Drug Discovery World

FEBRUARY 6, 2024

Verge Genomics’ potential amyotrophic lateral sclerosis (ALS) treatment VRG50635 is one of the first drugs to enter clinical trials that was entirely discovered and developed using an AI-enabled platform 6. “For By making lab automation as easy as using a smartphone, the Flex robot democratises access to automation in life sciences research.”

Marketing 69

Marketing Medicine Genome Genomics 69

Drug Discovery World

JULY 15, 2022

The first complete, gapless sequence of a human genome was published 1 April 2022 in a special issue of the journal Science 1. While The Human Genome Project mapped about 92% of the human genome two decades ago, sequencing the last 8% of the genome proved highly challenging.

Genome 52

Genome Genomics DNA Containment 52

XTalks

NOVEMBER 7, 2022

Liquid biopsy tests in oncology involve isolating entities such as circulating tumor cells (CTC), circulating tumor DNA (ctDNA) and tumor-derived exosomes. These tumor-derived entities are used to derive genomic and proteomic data. The cfDNA that originates from tumors is called circulating tumor DNA (ctDNA).

Clinical Trials 98

Clinical Trials Clinical Trials Trials FDA Approval 98

Delveinsight

JANUARY 14, 2021

The study’s primary result will be the proportion of patients attaining a functional treatment, defined as an off-therapy loss of hepatitis B surface antigen (HBsAg) and HBV DNA from the serum. The treatment, VERVE-101, is a base editor; that is, it does not cut DNA as CRISPR gene editing systems do.

Gene Editing 40

Gene Editing Gene Genetics DNA 40

XTalks

DECEMBER 4, 2023

The vectors can potentially cause cancer by inserting genetic material into a patient’s genome, particularly near cancer-related DNA sequences or suppressors​​​​.

Gene Therapy 69

Gene Therapy Gene Clinical Trials Clinical Trials 69

XTalks

MAY 23, 2024

Eterovic brings much knowledge and experience to the table, having led the development of a new Oncology Diagnostic program at Eurofins Viracor that integrates the latest genomic profiling techniques. Eterovic highlights that the financial and logistical barriers to comprehensive genomic profiling are high but not impossible to overcome.

Genetics 114

Genetics Research Genome Genomics 114

Roots Analysis

AUGUST 28, 2022

As a result, industry and non-industry stakeholders, are on the lookout for advanced platforms that can simultaneously capture the arrangement of multiple biomolecules (DNA, RNA, proteins and others) with single-cell or subcellular resolution. 70+ spatial Genomics solutions are developed by industry and non-industry players.

Genome 52

Genome Genomics RNA Genome Project 52

Pharmaceutical Technology

JUNE 4, 2023

Within the emerging innovation stage, cell therapy for ocular disorders, coronavirus vaccine components, and DNA polymerase compositions are disruptive technologies that are in the early stages of application and should be tracked closely. There are two main genes in the AAV genome, rep and cap, which encode nine different proteins.

Gene 262

Gene Gene Therapy Genetics DNA 262

XTalks

FEBRUARY 4, 2021

The power of leveraging clinical data to decipher disease mechanisms and fuel drug discovery has rapidly grown in the era of genomics and personalized medicine. Genuity Science focuses on population genomics as a tool to derive novel biological insights through partnerships with industry-leading pharmaceutical and biotech companies.

Research 98

Research Biobanking Drugs Genome 98

XTalks

AUGUST 12, 2020

Work from different fields, including evolutionary biology, suggest that there are four fundamental building blocks of life: DNA and RNA (nucleic acids), protein, lipids and sugars.

RNA 52

RNA Protein DNA In-Vivo 52

XTalks

SEPTEMBER 30, 2020

In the first study , Casanova’s team found that a B cell auto-immune phenocopy of inborn errors of type I IFN immunity underlies life-threatening COVID-19 pneumonia in at least 2.6 The team sequenced DNA from 659 critically ill COVID-19 patients and 534 controls with mild or asymptomatic disease. percent of women and 12.5

Antibody 135

Antibody Genetics Research In-Vitro 135