XTalks

MAY 22, 2024

PGI is a cutting-edge gene editing technology that allows for the insertion of large sequences of DNA with site-specific precision. John Finn, PhD Chief Scientific Officer Tome Biosciences Dr. Finn has over 20 years of experience in the gene therapy space with a focus on genome editing and delivery technologies.

Gene Editing 52

Gene Editing Life Science Gene Gene Therapy 52

The Pharma Data

JANUARY 31, 2021

NASDAQ: ILMN), the global leader in DNA sequencing and array-based technologies, and Sequoia Capital China , a leading investment firm, today announced a collaboration to catalyze the startup ecosystem in China with the launch of the Sequoia Capital China Intelligent Healthcare Genomics Incubator, Powered by Illumina.

Genome 52

Genome Genomics Life Science DNA 52

Roots Analysis

AUGUST 28, 2022

As a result, industry and non-industry stakeholders, are on the lookout for advanced platforms that can simultaneously capture the arrangement of multiple biomolecules (DNA, RNA, proteins and others) with single-cell or subcellular resolution. 70+ spatial Genomics solutions are developed by industry and non-industry players.

Genome 52

Genome Genomics RNA Genome Project 52

XTalks

MAY 23, 2024

Eterovic brings much knowledge and experience to the table, having led the development of a new Oncology Diagnostic program at Eurofins Viracor that integrates the latest genomic profiling techniques. Eterovic highlights that the financial and logistical barriers to comprehensive genomic profiling are high but not impossible to overcome.

Genetics 114

Genetics Research Genome Genomics 114

XTalks

MAY 12, 2021

In this episode, Ayesha discusses a new tool that uses CRISPR to modulate gene expression without editing DNA sequences. The team debates the ethical considerations around epigenetic therapies and genome editing, and how scientific communications should be improved to help educate the public on complex medical breakthrough.

Life Science 40

Life Science Gene Expression Gene DNA 40

XTalks

FEBRUARY 4, 2021

The power of leveraging clinical data to decipher disease mechanisms and fuel drug discovery has rapidly grown in the era of genomics and personalized medicine. Genuity Science focuses on population genomics as a tool to derive novel biological insights through partnerships with industry-leading pharmaceutical and biotech companies.

Research 98

Research Biobanking Drugs Genome 98

XTalks

SEPTEMBER 9, 2021

It was found that the gene being delivered through the therapy had integrated into the genomes of six of the seven mice that were administered the highest dose. Although a rare event that occurs at very low frequency, AAV vectors can integrate into genomes through homologous recombination.

Gene Therapy 105

Gene Therapy Gene Genome Genomics 105

pharmaphorum

OCTOBER 2, 2020

Sophia Genetics specialises in artificial intelligence-powered data mining tools that can sift through genomics data generated in DNA sequencing studies at academic institutions, and look for patterns that can be used to provide insights into diseases, guide treatment and signpost the development of new therapies.

Genetics 59

Genetics Genome Genomics Life Science 59

XTalks

MAY 10, 2022

Somatic variant classification and interpretation are the most time-consuming steps of tumor genomic profiling,” said the co-author of the study Marilyn M. Li, MD, Professor of Pathology and Laboratory Medicine, Director of Cancer Genomic Diagnostics. CancerVar provides a powerful tool that automates these two critical steps.

Bioinformatics 98

Bioinformatics Development Gene Genome 98

The Pharma Data

OCTOBER 19, 2020

20, 2020 /PRNewswire/ — Caris Life Sciences® , a leading innovator in molecular science focused on fulfilling the promise of precision medicine, announced today that Winship Cancer Institute of Emory University (Winship) has joined Caris’ Precision Oncology Alliance (The Alliance/POA). .”

Life Science 52

Life Science Clinical Trials Clinical Trials RNA 52

Pharmaceutical Technology

JUNE 21, 2023

Life sciences venture capital firm Flagship Pioneering has unveiled Empress Therapeutics, a small molecule drug development startup. Empress benefits from a wealth of clinical data, and recent advances in genomics, artificial intelligence (AI) and synthetic biology. A modest team of fewer than 30 people is behind the startup.

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Development Drugs Protein Life Science 130

XTalks

APRIL 5, 2021

Bioinformatics jobs are commonly found in the fields of computer information science, pharmaceuticals, biotechnology, medical technology, computational biology, proteomics and medical informatics. The Human Genome Project could not have succeeded without the use of bioinformatics. How to Become a Bioinformatics Analyst.

Bioinformatics 59

Bioinformatics Engineer Scientist Genome 59

pharmaphorum

DECEMBER 9, 2022

Canada’s Varient , developing a rare disease patient community-sourced patient-reported outcome (PRO) and RWE platform. PharmStars is accepting applications until 14 January 14 for its next cohort in spring 2023, on the theme of innovations in women’s health and health equity.

Life Science 52

Life Science DNA Genome Genomics 52

Pharmaceutical Technology

MARCH 29, 2023

On March 28, the UK government announced that four UK life sciences companies will receive £277 million to help fund and advance manufacturing projects in medical diagnostics and human medicines. This is the first big spend being made from the UK’s Life Sciences Innovative Manufacturing Fund (LSIMF).

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Life Science Manufacturing Gene Therapy Medicine 276

The Pharma Data

DECEMBER 22, 2020

and European Union, this presents a compelling option to patients, their families, and medical professionals to minimize the diagnostic odyssey often faced in clinical genetic testing settings,” said Kevin Meldrum, general manager and vice president of Agilent’s Genomics Solutions Division. About Agilent Technologies.

Genome 40

Genome Genomics Genetics In-Vitro 40

XTalks

MARCH 24, 2021

The research team conducted a genome-wide association study (GWAS) for eye color, the largest of its kind to date, which involved the analysis of 195,000 individuals across Europe and Asia. The analysis uncovered 61 discrete genomic regions, with 50 of them being newly identified regions, associated with eye color variation.

Genetics 59

Genetics Gene Genome Genomics 59

Delveinsight

JANUARY 14, 2021

The study’s primary result will be the proportion of patients attaining a functional treatment, defined as an off-therapy loss of hepatitis B surface antigen (HBsAg) and HBV DNA from the serum. The treatment, VERVE-101, is a base editor; that is, it does not cut DNA as CRISPR gene editing systems do.

Gene Editing 40

Gene Editing Gene Genetics DNA 40

Pharmaceutical Technology

FEBRUARY 3, 2023

The field of genomic medicine has reached a true turning point. The established method for this process is a triple transfection using three different DNA plasmids. More efficient, suspension-based cell culture processes are urgently needed in the now fast-developing genomic medicine space.

Genome 244

Genome Genomics Medicine Gene Therapy 244

The Pharma Data

APRIL 11, 2023

About Bayer Bayer is a global enterprise with core competencies in the life science fields of health care and nutrition. The company’s approach to research prioritizes targets and pathways with the potential to impact the way that cancer is treated.

Research 40

Research Clinical Trials Clinical Trials Trials 40

pharmaphorum

OCTOBER 12, 2022

David Del Bourgo (CEO and co-founder, Whitelab Genomics) has always been passionate about introducing disruptive, innovative technologies to markets. We founded Whitelab Genomics after realising the potential to use data, data science, and AI in a more systematic way to develop genomic therapies,” Del Bourgo says.

Genome 105

Genome Genomics Medicine Development 105

Pharmaceutical Technology

JUNE 4, 2023

Within the emerging innovation stage, cell therapy for ocular disorders, coronavirus vaccine components, and DNA polymerase compositions are disruptive technologies that are in the early stages of application and should be tracked closely. There are two main genes in the AAV genome, rep and cap, which encode nine different proteins.

Gene 262

Gene Gene Therapy Genetics DNA 262

XTalks

MARCH 8, 2022

On International Women’s Day, Xtalks is celebrating women’s leadership in the life sciences by highlighting some of the female leaders at the forefront of scientific discovery, as well as the continuing challenges of attaining more equitable representation. Challenges in Women’s Leadership.

Life Science 105

Life Science Gene Therapy DNA Vaccination 105

XTalks

MAY 4, 2021

The tool targets the epigenome, the collection of DNA modifications in a cell such as methylation and post-translational histone modifications. These modifications regulate gene expression without changing the sequence or structure of DNA. DNA methylation occurs endogenously in all mammalian cells in response to various stimuli.

DNA 98

DNA Gene Gene Silencing Genome 98

XTalks

NOVEMBER 7, 2022

Liquid biopsy tests in oncology involve isolating entities such as circulating tumor cells (CTC), circulating tumor DNA (ctDNA) and tumor-derived exosomes. These tumor-derived entities are used to derive genomic and proteomic data. The cfDNA that originates from tumors is called circulating tumor DNA (ctDNA).

Clinical Trials 98

Clinical Trials Clinical Trials Trials FDA Approval 98

XTalks

JUNE 16, 2023

. “Companion diagnostics are high-quality, well-validated genomic tests that provide critical information to help oncologists make informed treatment decisions for their patients,” said Mia Levy, MD, PhD, chief medical officer at Foundation Medicine. ” What is FoundationOne Liquid CDx?

FDA Approval 97

FDA Approval Genome Genomics DNA 97

pharmaphorum

AUGUST 31, 2022

The key to why this technology could become central to gene editing is due to the specificity with which it can edit DNA and that it is also a relatively cheap process, compared with existing technologies. Tessera emerged from Flagship Pioneering, a venture capital company responsible for launching life science companies.

Gene Therapy 98

Gene Therapy Gene Gene Editing DNA 98

Pharmaceutical Technology

MAY 8, 2023

Within the emerging innovation stage, cell therapy for ocular disorders, coronavirus vaccine components, and DNA polymerase compositions are disruptive technologies that are in the early stages of application and should be tracked closely.

Genetics 130

Genetics DNA Genetic Engineering Antibody 130

XTalks

MAY 4, 2021

The tool targets the epigenome, the collection of DNA modifications in a cell such as methylation and post-translational histone modifications. These modifications regulate gene expression without altering the sequence or structure of DNA. DNA methylation occurs endogenously in all mammalian cells in response to various stimuli.

DNA 52

DNA Gene Gene Silencing Genome 52

XTalks

SEPTEMBER 30, 2020

In the first study , Casanova’s team found that a B cell auto-immune phenocopy of inborn errors of type I IFN immunity underlies life-threatening COVID-19 pneumonia in at least 2.6 The team sequenced DNA from 659 critically ill COVID-19 patients and 534 controls with mild or asymptomatic disease. percent of women and 12.5

Antibody 135

Antibody Genetics Research In-Vitro 135

XTalks

DECEMBER 1, 2020

Circulating DNA. The test is based on the identification of cancer-associated methylation signatures on DNA shed from tumor cells in the blood. The addition of methyl groups to DNA bases — namely cytosine and guanine in so-called ‘CpG islands’ — regulates the expression of genes.

DNA 64

DNA Genome Genomics Gene 64

The Pharma Data

JANUARY 5, 2021

Genomic surveillance is essential in fighting the pandemic. Illumina is pleased to partner with the CDC and Helix to provide accurate sequencing that can contribute to rapidly scaling genomic surveillance in the US to better understand the presence of B.1.1.7 variant in 4 samples from California and Florida. About Helix.

Genome 52

Genome Genomics Life Science Development 52

XTalks

NOVEMBER 30, 2023

The noteworthy candidate, EBT-101, is designed to eliminate HIV proviral DNA using CRISPR-Cas9 along with two guide RNAs (gRNAs). These dual gRNAs target three specific sites within the HIV genome, facilitating the removal of substantial portions of the viral DNA and minimizing the potential for viral escape.

FDA Approval 111

FDA Approval Gene Therapy Gene Clinical Trials 111

XTalks

AUGUST 12, 2020

Work from different fields, including evolutionary biology, suggest that there are four fundamental building blocks of life: DNA and RNA (nucleic acids), protein, lipids and sugars.

RNA 52

RNA Protein DNA In-Vivo 52

Pharmaceutical Technology

MAY 8, 2023

Within the emerging innovation stage, cell therapy for ocular disorders, coronavirus vaccine components, and DNA polymerase compositions are disruptive technologies that are in the early stages of application and should be tracked closely.

Antibody 147

Antibody Vaccination Vaccine Dermatology 147

XTalks

OCTOBER 26, 2023

The Flu versus COVID-19: Virology and Vaccines SARS-CoV-2 versus Influenza Virology Viruses contain genetic material that can either be RNA or DNA. An RNA genome enables the genetic material to mutate more rapidly. Both influenza and SARS-CoV-2 have RNA as their genetic material.

Vaccine 105

Vaccine Vaccination RNA Manufacturing 105

XTalks

MAY 12, 2022

The detergent will denature the proteins and result in the release of the viral genomic DNA. The developed primers or the capture oligonucleotides will target and bind to the viral DNA and thus, they will form a hybrid called an amplicon.

In-Vitro 52

In-Vitro DNA Development Genome 52

XTalks

OCTOBER 8, 2024

A gene contains instructions within our DNA. Today, it’s known that the human genome encodes over a thousand microRNAs, which play vital roles in how organisms grow, differentiate and operate, uncovering a new layer of complexity in genetic regulation. However, microRNAs can bind to this mRNA, preventing it from functioning.

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Regulation Genetics Scientist RNA 52