Drug Discovery World

OCTOBER 3, 2023

Earlier this year, DDW hosted a webinar, ‘A comprehensive guide to using adeno-associated virus (AAV) vectors in gene therapy’, supported by Azenta Life Sciences. This all creates numerous challenges for the market. Dr O’Hara also provided an AAV plasmid preparation case study. Why are those important?

Gene Therapy 52

Gene Therapy Gene Life Science Bioinformatics 52

Drug Discovery World

FEBRUARY 6, 2024

Verge Genomics’ potential amyotrophic lateral sclerosis (ALS) treatment VRG50635 is one of the first drugs to enter clinical trials that was entirely discovered and developed using an AI-enabled platform 6. “For By making lab automation as easy as using a smartphone, the Flex robot democratises access to automation in life sciences research.”

Marketing 69

Marketing Medicine Genome Genomics 69

XTalks

DECEMBER 20, 2023

As we step into 2024, the life sciences continue to evolve at an unprecedented pace, driven by technological innovation, a deeper understanding of human biology and the application of new technologies in areas like drug development and health wearables. The global wearable medical devices market size was valued at $73.77

Life Science 119

Life Science Gene Editing Development Clinical Trials 119

Drug Discovery World

OCTOBER 16, 2023

Maina Bhaman, Partner at Sofinnova Partners, says: “The UK is an attractive space for drug discovery companies and a prime environment for investment due to its talent, infrastructure, and genomics research. The UK, and specifically Wales, has been hugely supportive of life sciences and building a highly collaborative network.

Drugs 75

Drugs Life Science Gene Therapy Genome 75

The Pharma Data

JANUARY 5, 2021

Genomic surveillance is essential in fighting the pandemic. Illumina is pleased to partner with the CDC and Helix to provide accurate sequencing that can contribute to rapidly scaling genomic surveillance in the US to better understand the presence of B.1.1.7 variant in 4 samples from California and Florida. About Helix.

Genome 52

Genome Genomics Life Science Development 52

Drug Discovery World

JUNE 5, 2023

The panel was moderated by Alexander Nuyken, Head Life Sciences Markets Europe, Middle East & Africa, JLL. I consider one of my responsibilities to advocate the advent of a new era for 3D genomics. Our final goal is to pioneer the 3D genomic field and demonstrate the impact on precision medicine.

Genome 52

Genome Genomics Life Science Genetics 52

Drug Discovery World

FEBRUARY 13, 2023

What is important is how we use it, and SLAS2023 is taking the necessary next steps through a diverse range of talks and presentations, which ask: How has life sciences technology pushed innovation to boost the drug discovery process? How can technology help drug discovery research get to market faster and at optimum efficiency?

Genome 52

Genome Genomics Life Science Drugs 52

Drug Discovery World

JANUARY 30, 2023

DDW Editor Reece Armstrong takes a look at Lithuania’s life sciences sector and what it means for start-ups operating in the country. Despite consisting of largely small enterprises, Lithuania is still home to some large players in the life sciences sector including Thermo Fisher Scientific, Teva and Northway Biotech.

Life Science 98

Life Science Genome Genomics Development 98

The Pharma Data

OCTOBER 19, 2020

20, 2020 /PRNewswire/ — Caris Life Sciences® , a leading innovator in molecular science focused on fulfilling the promise of precision medicine, announced today that Winship Cancer Institute of Emory University (Winship) has joined Caris’ Precision Oncology Alliance (The Alliance/POA). .”

Life Science 52

Life Science Clinical Trials Clinical Trials RNA 52

Pharmaceutical Technology

FEBRUARY 3, 2023

The field of genomic medicine has reached a true turning point. Cell culture challenges The viral vectors used in the gene therapies currently on the market are produced in adherent human embryonic HEK-293 cell culture. The established method for this process is a triple transfection using three different DNA plasmids.

Genome 244

Genome Genomics Medicine Gene Therapy 244

Drug Discovery World

JULY 11, 2023

Tim Lowery , President, JSR Life Sciences, asks whether artificial intelligence can do for life sciences what it has done in other sectors and whether these tools can keep up with the complexities of human biology. So, where do we go from here to realise their potential in life sciences?

Big Data 40

Big Data Development Life Science Drugs 40

The Pharma Data

DECEMBER 22, 2020

“We are truly excited and humbled to bring the power of diagnostic microarray testing to the Japanese market. NYSE: A) is a global leader in life sciences, diagnostics, and applied chemical markets, delivering insight and innovation toward improving the quality of life. About Agilent Technologies.

Genome 40

Genome Genomics Genetics In-Vitro 40

XTalks

NOVEMBER 7, 2022

Liquid biopsy tests in oncology involve isolating entities such as circulating tumor cells (CTC), circulating tumor DNA (ctDNA) and tumor-derived exosomes. These tumor-derived entities are used to derive genomic and proteomic data. The cfDNA that originates from tumors is called circulating tumor DNA (ctDNA).

Clinical Trials 98

Clinical Trials Clinical Trials Trials FDA Approval 98

Delveinsight

JANUARY 14, 2021

The multi-arm trial will gauge various combinations of selgantolimod, Gilead’s investigational TLR-8 agonist; VIR-2218, Vir’s investigational small interfering ribonucleic acid (siRNA); and a commercially-sourced, marketed PD-1 antagonist. The round was led by Alaska Permanent Fund Corp.,

Gene Editing 40

Gene Editing Gene Genetics DNA 40

XTalks

DECEMBER 4, 2023

In a statement outlining its investigation, the FDA said it received reports of the T-cell malignancies from clinical trials and post-marketing safety monitoring. The vectors can potentially cause cancer by inserting genetic material into a patient’s genome, particularly near cancer-related DNA sequences or suppressors​​​​.

Gene Therapy 69

Gene Therapy Gene Clinical Trials Clinical Trials 69

Roots Analysis

AUGUST 28, 2022

As a result, industry and non-industry stakeholders, are on the lookout for advanced platforms that can simultaneously capture the arrangement of multiple biomolecules (DNA, RNA, proteins and others) with single-cell or subcellular resolution. 70+ spatial Genomics solutions are developed by industry and non-industry players.

Genome 52

Genome Genomics RNA Genome Project 52

Drug Discovery World

AUGUST 8, 2023

In the global pharmaceuticals market, India ranks third worldwide for production by volume and the domestic pharmaceutical market is expected to reach US$120-130 billion by 2030 1. A report by PWC shared that the pharmaceutical industry’s main markets are under ‘serious pressure’ 7.

Research 52

Research Drugs Genome Genomics 52

The Pharma Data

APRIL 11, 2023

The oncology franchise at Bayer includes six marketed products across various indications and several compounds in different stages of clinical development. About Bayer Bayer is a global enterprise with core competencies in the life science fields of health care and nutrition.

Research 40

Research Clinical Trials Clinical Trials Trials 40

XTalks

DECEMBER 13, 2023

Moreover, it has submitted global marketing authorization applications for mRNA-1345, a vaccine designed to prevent RSV-associated lower respiratory tract disease (RSV-LRTD) and acute respiratory disease (ARD), supported by favorable data from a predefined interim analysis. vaccine, mRNA-1273.815.

Genetics 111

Genetics Vaccination Vaccine DNA 111

Drug Discovery World

FEBRUARY 6, 2024

Scientific sessions Tuesday’s presentations spanned a range of topics, including functional genomics for target identification, next-generation proteomics, self-driving laboratories, the future of cell culture, and ‘lab on a particle’ technology.

Life Science 64

Life Science Genome Genomics RNA 64

Drug Discovery World

APRIL 29, 2024

Dr Andrew Lewis, Chief Scientific Officer; Kieron Hall, Chief Marketing Officer; and Eric Bironneau, Chief Business Officer, Quotient Sciences: Lewis has held various scientific leadership positions at Quotient and was previously Director of Novel Drug Delivery Technologies at Ipsen.

Drugs 52

Drugs Sales Gene Therapy Life Science 52

Drug Discovery World

APRIL 25, 2024

The market for cell line development is currently rising due to an increased focus by the life sciences sector on biopharmaceuticals and targeted therapies. According to Grand View Research, the global cell line development market was valued at $4.81 Bacterial cell lines such as E.

Development 59

Development Protein In-Vivo Life Science 59

Drug Discovery World

FEBRUARY 20, 2023

Indee Labs and GenScript have formed a research collaboration with the aim to develop a DNA knock-in kit for Hydropore to enable large transgene inserts above the 5kb limit for AAV.

Engineer 52

Engineer DNA Life Science Gene 52

Drug Discovery World

MARCH 6, 2024

Guiding neurological drug discovery and development to success The 20 years since the Human Genome Project has seen transformational advances in the molecular understanding of cancers and rare genetic diseases, leading to genetically informed, personalised selection of therapies and massively improved outcomes for many patients.

Genome 64

Genome Genomics Clinical Trials Clinical Trials 64

XTalks

DECEMBER 1, 2020

Circulating DNA. The test is based on the identification of cancer-associated methylation signatures on DNA shed from tumor cells in the blood. The addition of methyl groups to DNA bases — namely cytosine and guanine in so-called ‘CpG islands’ — regulates the expression of genes.

DNA 64

DNA Genome Genomics Regulation 64

Drug Discovery World

AUGUST 10, 2022

By Mark White, Associate Director of Biopharma Product Marketing at Bio-Rad and Marwan Alsarraj, Biopharma Segment Manager, Digital Biology Group. Exactly three decades later, the first CAR T cell therapy hit the market. If the gene does not integrate into the genome, the cell will not become a CAR T cell.

Manufacturing 98

Manufacturing Gene Genome Genomics 98

pharmaphorum

AUGUST 31, 2022

After a recent approval, there are now three gene therapies available on the US market. Though there are still few commercial treatments, in terms of therapeutic potential, Ben Hargreaves finds that companies and investment firms are pushing for this number, and the overall market, to grow rapidly in the coming years. FDA backing.

Gene Therapy 91

Gene Therapy Gene Gene Editing DNA 91

Drug Discovery World

SEPTEMBER 6, 2022

Indeed, the growth of the cell and gene therapy market, coupled with the demand that the pandemic placed on manufacturing capacity, means the industry faces shortages of these crucial materials. The challenge for the market then, according to Boissel, is how much can a payor afford to pay upfront? .

Gene Therapy 52

Gene Therapy Gene Manufacturing Medicine 52

Drug Discovery World

APRIL 30, 2024

The biggest growth driver for mRNA therapeutics came from the Covid-19 pandemic, when mRNA-based vaccines proved effective in treating SARS-CoV-2, and pharmaceutical companies such as Pfizer/BioNTech and Moderna were successful in bringing these treatments to market. J Biomed Sci 2023;30;84.

RNA 52

RNA Protein Vaccination Vaccine 52

Drug Discovery World

OCTOBER 25, 2023

However, the ligation step is biased and inefficient because the enzymes that ligate the adapters, which are DNA and RNA sequences, prefer some sRNAs that the adapters are ligated to. RA: How accessible have NGS technologies become for life sciences researchers? RA: Can NGS improve the chances of a drug making it to market?

Bioinformatics 115

Bioinformatics Genetics RNA Drugs 115

XTalks

OCTOBER 26, 2023

variant was selected in June and within a few months, both Pfizer-BioNTech and Moderna were able to get vaccines for it to market by September, which Dr. Kierstead says is “astonishingly fast.” The Flu versus COVID-19: Virology and Vaccines SARS-CoV-2 versus Influenza Virology Viruses contain genetic material that can either be RNA or DNA.

Vaccination 105

Vaccination Vaccine RNA Manufacturing 105

XTalks

DECEMBER 24, 2020

The pandemic propelled the life science and healthcare sectors onto center stage, and they rose to the occasion against the most unprecedented health challenge in recent times. While COVID-19 has undoubtedly been the biggest story in the life science industry in 2020, it was a busy and positive year in many other areas.

Life Science 111

Life Science Vaccination Vaccine Gene 111

Pharmaceutical Technology

MARCH 29, 2023

On March 28, the UK government announced that four UK life sciences companies will receive £277 million to help fund and advance manufacturing projects in medical diagnostics and human medicines. This is the first big spend being made from the UK’s Life Sciences Innovative Manufacturing Fund (LSIMF).

Life Science 276

Life Science Manufacturing Gene Therapy Medicine 276

Pharmaceutical Technology

JUNE 21, 2023

Life sciences venture capital firm Flagship Pioneering has unveiled Empress Therapeutics, a small molecule drug development startup. Empress benefits from a wealth of clinical data, and recent advances in genomics, artificial intelligence (AI) and synthetic biology. A modest team of fewer than 30 people is behind the startup.

Development 130

Development Drugs Protein Life Science 130