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The Role of Oncology Biomarkers in Personalizing Hematology Treatment Plans

Worldwide Clinical Trials

Protein-based Biomarkers : Include proteins found in blood, tissues, or other bodily fluids that can indicate disease presence or progression. Protein-based biomarkers are the most widely used biomarkers in cancer screening and diagnosis.

Genetics 195
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Osimertinib Resistance and EGFR Mutations in NSCLC Treatment

Bioengineer

This mutation hinders the drug’s binding to the mutant EGFR protein. Osimertinib, however, can covalently bind to the T790M and cysteine-797 (C797) residue at the protein’s ATP binding site, overcoming resistance mechanisms. Real-world cohorts report a prevalence of C797 mutations between 11% and 29%.

Genomics 119
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Evolution in Hepatitis B and C Virus: Can we expect success similar to Hepatitis C in Hepatitis B as well?

Delveinsight

The first approved treatment for hepatitis C was a series of protein-based injections called recombinant interferon-alfa (IFNa). Interferons are naturally occurring proteins in the body; recombinant IFNa is the protein-based drug that works to mobilize the body’s natural immune system to fight disease. in January 2019.

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Molecular Diagnostic Tests: The Unsung Hero of Precise Clinical Decision Making

Roots Analysis

Molecular diagnostic tests refer to tests intended to detect specific sequences in human genomic samples, such as DNA or RNA, in order to diagnose a particular disease. The common types of molecular diagnostic tests include PCR, RT-PCR, DNA microarrays and next generation sequencing tests. What are Molecular Diagnostic Tests?

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Nutrigenomics: The Future of Personalized Nutrition

Roots Analysis

Recent advances in DNA sequencing technologies have led to significant developments in healthcare-focused research on precision medicine and diagnostics. Nutritional DNA testing helps in identifying foods that might lead to allergies or intolerance in an individual.

Genome 40