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As we step into 2024, the lifesciences continue to evolve at an unprecedented pace, driven by technological innovation, a deeper understanding of human biology and the application of new technologies in areas like drug development and health wearables.
On International Women’s Day, Xtalks is celebrating women’s leadership in the lifesciences by highlighting some of the female leaders at the forefront of scientific discovery, as well as the continuing challenges of attaining more equitable representation. Challenges in Women’s Leadership.
Abid Ansari, MBA Chief Financial Officer OncoC4 Abid Ansari is a finance executive with a more 20-year track record in the lifesciences industry encompassing corporate finance, fundraising, business development and investor relations experiences for public and private lifescience companies.
How did you get into lifesciences? After a few years, I decided I wanted to move into the commercial side of the business, so I completed an MBA and went on to hold various positions in Corporate Business Development, LifeScience and Healthcare. What has your career path been? Ultimately, this has to start at school.
Two-thirds – 67% – of lifesciences companies surveyed had not set a Net Zero target in 2022. Of those companies that set Net Zero targets, the lifesciences sector has an average target for 2037 – 11 years earlier than the cross-sector average of 2048. But there is also reason for optimism in the face of this challenge.
Aqueous droplet formation by liquid-liquid phase separation (or coacervation) in macromolecules is a hot topic in lifesciences research. Of these various macromolecules that form droplets, DNA is quite interesting because it is predictable and programmable, which are qualities useful in nanotechnology.
The deal will see Polyplus join the German lifescience group’s portfolio allowing the latter to leverage expertise in transfection reagents and plasmid DNA for gene therapy. to complete an in-house plasmid DNA facility in Marburg, Germany. “In In February 2023, the mRNA specialist BioNTech invested $43.8m
Dear pharma & lifesciences colleagues, It was a pleasure to welcome you to our webinar: PwC Pharma & LifeSciences Webinar: COVID-19 impact on the ITX and regulatory DNA. Attached below you can download the presentation. We look forward to meeting you again soon. We look forward to meeting you again soon.
If the past year is anything to go by, then 2022 will also be a year marked by continued innovations in the lifesciences. Here is a look at some lifescience trends to expect in the coming year, including key themes and topics in the pharmaceutical, biotechnology and medical device industries to keep an eye out for in 2022.
However, the variant viral genomes will still persist in the latent reservoir as provirus and can be detected with proviral DNA testing. In contrast to HIV RNA, HIV proviral DNA remains present in a patient’s cells even during virological suppression. Proviral DNA Genotyping. HIV Drug Resistance Testing.
Developed by MIT researchers Jonathan Gootenberg and Omar Abudayyeh, PASTE (Programmable Addition via Site-specific Targeting Elements) gene editing technology can insert genes as long as 36,000 DNA base pairs to liver cells in mice as well as several types of human cells.
The new figures – from the BioIndustry Association and Clarivate – were dominated by more than £1 billion in venture capital funding for UK biotech and lifesciences companies, headlined by DNA sequencing company Oxford Nanopore’s £195 million raise in May that was just shy of the £205 million record set by Immunocore in 2005.
Illumina, the world’s leading DNA sequencing and array-based technologies company, is partnering with Sequoia Capital China, an investment firm, to launch a lifesciences incubator in China. It is dubbed the Sequoia Capital China Intelligent Healthcare Genomics Incubator, Powered by Illumina.
Researchers at Nano LifeScience Institute (WPI-NanoLSI), Kanazawa University, have discovered how a protein called lamin A helps repair the protective barrier around a cell's DNA.
What can we learn from mummy DNA? The newest Nobel laureates got their phone calls from Stockholm this week, and STAT science writer Megan Molteni joins us to explain their prize-winning work in medicine and chemistry. Is Pfizer single-handedly propping up biotech? And how do you get molecules to “click”?
After months of vigorous deliberations, I’m thrilled to announce our 2023 STATUS List — the definitive roster of leaders in health, medicine, and the lifesciences whose work over the past year has advanced those fields. There were, of course, many contenders to choose from.
The opening of this new facility plays into the UK government’s LifeSciences Industrial Strategy. The strategy , underlines one of the government’s goals of increasing the UK’s manufacturing capacity for DNA-based therapeutics. The NHSBT hopes the CBC will increase the UK’s competitiveness within the market.
Within the emerging innovation stage, cell therapy for ocular disorders, coronavirus vaccine components, and DNA polymerase compositions are disruptive technologies that are in the early stages of application and should be tracked closely. Transcription of the cap gene is initiated from a single promoter termed p40.
PGI is a cutting-edge gene editing technology that allows for the insertion of large sequences of DNA with site-specific precision. Subscribe to the Xtalks LifeScience Podcast to never miss a new episode. PGI is a revolutionary approach for the development of potentially curative cell and integrative gene therapies.
Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Researchers chemically synthesize a mirror-image of Pfu DNA polymerase.A
Illumina , the world’s leading DNA sequencing and array-based technologies company, is partnering with Sequoia Capital China, an investment firm, to launch a lifesciences incubator in China. The focus will be on building lifescience startups specializing in genomics.
These primarily include oxidative stress caused by the accumulation of reactive oxygen species, telomere shortening, and deoxyribonucleic acid (DNA)/histone methylation patterns. Telomeres are the buffer regions of DNA that cap the ends of chromosomes and prevent chromosomal attrition during DNA replication.
The tool targets the epigenome, the collection of DNA modifications in a cell such as methylation and post-translational histone modifications. These modifications regulate gene expression without changing the sequence or structure of DNA. DNA methylation occurs endogenously in all mammalian cells in response to various stimuli.
Exact Sciences’ campaign is appropriately called “Mission to Screen” and includes a TV commercial featuring Couric and her daughter, along with other people that Couric is seen speaking to about their reasons for screening for colon cancer. The ad highlights Exact Sciences’ Cologuard, a DNA-based stool test for colon cancer detection.
Viral vectors have traditionally been used in gene editing where the shells of viruses carry the template DNA into cells, but this method has its disadvantages. The CRISPR-Cas9 system works by having “spacer” sequences transcribed into short RNA sequences that can guide the system to the matching target in the DNA sequence of a cell.
In this episode, Ayesha discusses a new tool that uses CRISPR to modulate gene expression without editing DNA sequences. Subscribe to the Xtalks LifeScience Podcast to never miss a new episode. New Study Looks at Effects of ADHD Drugs in Preschoolers.
Originally discovered in bacteria as a defense mechanism against pathogens, CRISP/Cas9 has made it possible to make exquisitely detailed and precise alterations to DNA sequences on demand, and as a tool for molecular biology has already transformed research into diseases and drug discovery.
Within the emerging innovation stage, cell therapy for ocular disorders, coronavirus vaccine components, and DNA polymerase compositions are disruptive technologies that are in the early stages of application and should be tracked closely.
The drug candidate targets DNA-dependent protein kinase (DNA-PK). Merck KG, is a science and technology company. The company serves healthcare, performance materials, and lifesciences markets. The drug candidate is administered through the oral route in the form of capsule and tablet. It is a new chemical entity.
The drug candidate targets DNA-dependent protein kinase (DNA-PK). Merck KG, is a science and technology company. The company serves healthcare, performance materials, and lifesciences markets. The drug candidate is administered through the oral route in the form of capsule and tablet. It is a new chemical entity.
Within the emerging innovation stage, cell therapy for ocular disorders, coronavirus vaccine components, and DNA polymerase compositions are disruptive technologies that are in the early stages of application and should be tracked closely.
2021 was a record year for investments in UK biotech companies, consolidating the country’s position as one of Europe’s top lifescience hubs and apparently shrugging off the effects of the pandemic and Brexit. “History has handed the UK two world-leading sectors: lifesciences and finance.
In the broader cancer detection space, Grail, in partnership with Quest Diagnostics , recently rolled out its Galleri multi-cancer early detection (MCED) test, which screens for over 50 cancers through a simple blood draw by analyzing circulating tumor DNA (ctDNA).
The leading global lifescience company is set to introduce Resolution Bio’s ctDx Lung assay , a non-invasive liquid biopsy test for patients with non-small cell lung cancer (NSCLC). The test involves isolating circulating tumor DNA in the blood and sequencing it to look for relevant gene mutations.
The data show that 2020 was a “watershed year” for UK biotech , according to BIA chief executive Steve Bates, who said the uplift was seen across the lifesciences category, not just organisations that were directly involved in the COVID-19 response. The post UK biotech investment at record levels amid COVID-19 appeared first on.
But for many lifesciences organisations, these tools are either not yet fully adopted or are not being put to good use within their regulatory functions. The Accenture Technology Vision survey found just one-third of 103 lifesciences executives have high confidence in their data and validate it extensively.
Within the emerging innovation stage, cell therapy for ocular disorders, coronavirus vaccine components, and DNA polymerase compositions are disruptive technologies that are in the early stages of application and should be tracked closely.
The Biotechnology and Biological Sciences Research Council (BBSRC), part of UK Research and Innovation (UKRI), works with universities, research organisations, businesses, charities, and government to develop a supportive ecosystem. Today researchers are attaching only a portion of the DNA or mRNA of the virus to a harmless molecule.
During the pandemic, the Government of Canada acknowledged recent shortcomings in the lifesciences and biomanufacturing sectors. Biovectra is also working to strike research partnerships and look for new development opportunities for lifescience professionals and those in the field of biomanufacturing.
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Dr. Stanley Plotkin , Professor Emeritus at The Wistar Institute, said, “INOVIO’s DNA vaccine appeared to be quite safe with few significant reactions but yet induced both antibody and T cell responses to SARS-CoV-2.”
About INOVIO’s DNA Medicines Platform.
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Circulating DNA. The test is based on the identification of cancer-associated methylation signatures on DNA shed from tumor cells in the blood. The addition of methyl groups to DNA bases — namely cytosine and guanine in so-called ‘CpG islands’ — regulates the expression of genes.
Related: Transforming Eye Care: Innovating New Glaucoma and Dry Eye Disease Treatments — Featuring Pierre Simon, VP Marketing, Sight Sciences – Xtalks LifeScience Podcast Ep. Secondly, other funded research is exploring differential gene expression regulated by DNA methylation.
This expansion is triggered by somatic mutations — changes that occur in the DNA post-fertilization and are not inherited from parent to offspring. The ideal approach to distinguish these mutations involves comprehensive genomic profiling, where both tumor DNA and germline (blood) DNA are sequenced.
The Burnaby, BC-based company developed the oral DNA-based vaccine using its proprietary bacTRL Gene Therapy Platform, which uses genetically modified bifidobacteria as carriers of genetic vaccine elements on a DNA plasmid. Related: Red Meat Allergy Test Gets FDA Clearance. “We
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