Pharmaceutical Technology

MARCH 1, 2023

The drug candidate targets DNA-dependent protein kinase (DNA-PK). Merck KG, is a science and technology company. The company serves healthcare, performance materials, and life sciences markets. The drug candidate is administered through the oral route in the form of capsule and tablet.

Gene Editing 100

Gene Editing DNA Cosmetics Life Science 100

XTalks

MAY 4, 2021

The tool targets the epigenome, the collection of DNA modifications in a cell such as methylation and post-translational histone modifications. These modifications regulate gene expression without changing the sequence or structure of DNA. DNA methylation occurs endogenously in all mammalian cells in response to various stimuli.

DNA 98

DNA Gene Gene Silencing Genomics 98

Pharmaceutical Technology

APRIL 18, 2023

Within the emerging innovation stage, cell therapy for ocular disorders, coronavirus vaccine components, and DNA polymerase compositions are disruptive technologies that are in the early stages of application and should be tracked closely.

Protein 147

Protein Vaccine Vaccination Production 147

XTalks

JULY 20, 2022

The production facility will be equipped to develop and manufacture plasmid DNA, nucleic acids, recombinant proteins and other therapeutics produced through methods involving microbial fermentation. Related: Biovectra to Build First mRNA Vaccine and Drug Manufacturing Plant in Canada. In addition to a $39.8

Vaccination 105

Vaccination Vaccine Manufacturing Life Science 105

XTalks

NOVEMBER 6, 2020

The Burnaby, BC-based company developed the oral DNA-based vaccine using its proprietary bacTRL Gene Therapy Platform, which uses genetically modified bifidobacteria as carriers of genetic vaccine elements on a DNA plasmid. Related: Red Meat Allergy Test Gets FDA Clearance. “We

Clinical Trials 75

Clinical Trials Clinical Trials Vaccination Vaccine 75

XTalks

NOVEMBER 23, 2021

The CDMO’s new manufacturing facility will have the capability to develop and manufacture nucleic acids, recombinant proteins and therapeutics expressed via microbial fermentation. During the pandemic, the Government of Canada acknowledged recent shortcomings in the life sciences and biomanufacturing sectors.

Manufacturing 98

Manufacturing Vaccination Vaccine Drugs 98

Pharmaceutical Technology

NOVEMBER 22, 2022

The mission was first put forward during the UK’s G7 Presidency of June 2021, with support from representatives of the life sciences industry. Messenger RNA vaccines contain nucleic acids that code for a specific protein, or target antigen, related to a virus or disease. The UK Government is behind this effort.

Manufacturing 130

Manufacturing Vaccination Vaccine RNA 130

Pharmaceutical Technology

MAY 8, 2023

Within the emerging innovation stage, cell therapy for ocular disorders, coronavirus vaccine components, and DNA polymerase compositions are disruptive technologies that are in the early stages of application and should be tracked closely.

Antibody 147

Antibody Vaccine Vaccination Dermatology 147

XTalks

MARCH 13, 2024

Related: Transforming Eye Care: Innovating New Glaucoma and Dry Eye Disease Treatments — Featuring Pierre Simon, VP Marketing, Sight Sciences – Xtalks Life Science Podcast Ep. Secondly, other funded research is exploring differential gene expression regulated by DNA methylation.

Gene Therapy 111

Gene Therapy Gene Life Science DNA 111

XTalks

SEPTEMBER 30, 2020

The two studies were recently published online in the journal Science, both of which were led by Jean-Laurent Casanova, an infectious disease geneticist at Rockefeller University. Upon encountering a virally-infected cell, interferons trigger an immediate local response, causing infected cells to produce proteins that fight the virus.

Antibody 135

Antibody Genetics Research In-Vitro 135

The Pharma Data

DECEMBER 23, 2020

” Dr. Stanley Plotkin , Professor Emeritus at The Wistar Institute, said, “INOVIO’s DNA vaccine appeared to be quite safe with few significant reactions but yet induced both antibody and T cell responses to SARS-CoV-2.” About INOVIO’s DNA Medicines Platform. mg and 2.0

DNA 40

DNA Vaccination Vaccine Immune Response 40

pharmaphorum

AUGUST 31, 2022

The key to why this technology could become central to gene editing is due to the specificity with which it can edit DNA and that it is also a relatively cheap process, compared with existing technologies. Tessera emerged from Flagship Pioneering, a venture capital company responsible for launching life science companies.

Gene Therapy 98

Gene Therapy Gene Gene Editing DNA 98

XTalks

DECEMBER 13, 2023

Bolstered by world-class R&D capabilities, a highly productive scientific platform and an established management team, Alpine is dedicated to crafting first- or best-in-class multifunctional immunotherapies through distinctive protein engineering technologies, all aimed at enhancing the quality of life for patients.

Genetics 111

Genetics Vaccination Vaccine DNA 111

XTalks

MAY 4, 2021

The tool targets the epigenome, the collection of DNA modifications in a cell such as methylation and post-translational histone modifications. These modifications regulate gene expression without altering the sequence or structure of DNA. DNA methylation occurs endogenously in all mammalian cells in response to various stimuli.

DNA 52

DNA Gene Gene Silencing Genomics 52

The Pharma Data

OCTOBER 19, 2020

20, 2020 /PRNewswire/ — Caris Life Sciences® , a leading innovator in molecular science focused on fulfilling the promise of precision medicine, announced today that Winship Cancer Institute of Emory University (Winship) has joined Caris’ Precision Oncology Alliance (The Alliance/POA). .

Life Science 52

Life Science Clinical Trials Clinical Trials RNA 52

XTalks

NOVEMBER 30, 2023

Its mechanism of action involves blocking the protein shell (capsid) of the HIV-1 virus, disrupting multiple crucial stages of the viral lifecycle. The noteworthy candidate, EBT-101, is designed to eliminate HIV proviral DNA using CRISPR-Cas9 along with two guide RNAs (gRNAs).

FDA Approval 111

FDA Approval Gene Therapy Gene Clinical Trials 111

Roots Analysis

AUGUST 28, 2022

Furthermore, several live cell imaging and non-destructive fluorescence histological methods measure limited number of biomarkers at a time and the tags introduced may interfere with the natural function of genes and proteins. For more details on this emerging domain, check out the following report : SPATIAL GENOMICS MARKET.

Genomics 52

Genomics Genome RNA Genome Project 52

XTalks

FEBRUARY 11, 2021

The drugmaker is targeting various steps in the manufacturing process, beginning right at the DNA stage, which is required as the template from which the mRNA for the SARS-CoV-2 spike protein in the vaccine is made. This involves testing and quality assurance of the DNA to make sure its integrity meets the strict vaccine requirements.

Manufacturing 52

Manufacturing Vaccination Vaccine DNA 52

XTalks

MAY 10, 2022

CancerVar users can query the clinical interpretations of somatic variants using the chromosome position, complementary DNA (cDNA) change or protein change. In addition, CancerVar helps generate reproducible and precise clinical interpretations.

Bioinformatics 98

Bioinformatics Development Gene Genomics 98

XTalks

MARCH 10, 2021

The T cell test from Adaptive Biotechnologies detects DNA sequences from T cells, specifically sequencing T cell receptors (TCR) on CD8+ T cells. Like other rapid antigen tests, Cue’s test also detects the nucleocapsid protein antigen from SARS-CoV-2, and not the more notorious spike protein of the virus.

Protein 98

Protein RNA Antibody Production 98

XTalks

NOVEMBER 7, 2022

Liquid biopsy tests in oncology involve isolating entities such as circulating tumor cells (CTC), circulating tumor DNA (ctDNA) and tumor-derived exosomes. The cfDNA that originates from tumors is called circulating tumor DNA (ctDNA). These tumor-derived entities are used to derive genomic and proteomic data.

Clinical Trials 98

Clinical Trials Clinical Trials Trials FDA Approval 98

XTalks

AUGUST 12, 2020

Studies have identified the presence of two types of HIV-infected CD4+ T cells: ‘Transcriptionally inactive’ cells that do not typically produce viral RNA or viral proteins. Fucosylation is the attachment of a specific sugar molecule called fucose to proteins on the surface of cells. T Cell Glycomic Signatures in HIV.

RNA 52

RNA Protein DNA In-Vivo 52

XTalks

OCTOBER 26, 2023

The Flu versus COVID-19: Virology and Vaccines SARS-CoV-2 versus Influenza Virology Viruses contain genetic material that can either be RNA or DNA. This means COVID-19 can quickly produce viral proteins once inside the host cell, which may make its replication cycle faster than influenza. remains the dominant variant.

Vaccination 105

Vaccination Vaccine RNA Manufacturing 105

XTalks

OCTOBER 8, 2024

A gene contains instructions within our DNA. To activate these instructions, cells create a copy called messenger RNA (mRNA), which exits the nucleus and directs the cell’s machinery to produce a specific protein. Once in the shadows of DNA, interest in RNA has been increasing within both scientific and public circles.

Regulation 52

Regulation Genetics Scientist RNA 52

XTalks

AUGUST 2, 2023

Johnson & Johnson’s Top 5 Best-Selling Drugs of 2022: 1) Stelara (ustekinumab) Stelara is an immunosuppressant biologic therapy that blocks the IL-12 and IL-23 proteins that play a role in plaque psoriasis and Crohn’s disease. The monoclonal antibody targets CD20, a protein found on the surface of B lymphocytes (B cells).

Sales 98

Sales Manufacturing FDA Approval Life Science 98

XTalks

DECEMBER 13, 2023

The CRISPR system is dubbed to be molecular “scissors” that can cut out parts of genes that are abnormal, deactivating or replacing them with new strands of normal DNA. This has tremendous potential for curing diseases that are caused by faulty/mutated genes. It also affects Hispanic Americans, but at a lower prevalence.

Gene Therapy 98

Gene Therapy Gene FDA Approval In-Vivo 98

XTalks

DECEMBER 27, 2022

Then, the cells translate the DNA sequence of the gene and secrete high amounts of the protein interferon alfa-2b. This protein is naturally occurring in the human body and the body uses it to fight cancer. The adenovirus vector enters the cells of the bladder wall and releases the gene interferon alfa-2b.

Gene Therapy 52

Gene Therapy FDA Approval Gene Clinical Trials 52

XTalks

FEBRUARY 5, 2024

In the dynamic landscape of oncology therapeutics, understanding the trends and performances of leading drugs is crucial for stakeholders across the healthcare and life sciences sectors. The top 40 best-selling oncology drugs in 2023, informed by 2022 sales statistics, mark significant milestones in cancer treatment and research.

FDA Approval 101

FDA Approval Drugs Sales Development 101

XTalks

DECEMBER 4, 2023

CAR T-cell therapies, which have been transformative in several blood cancers, involve extracting a patient’s own T cells, genetically modifying them with a chimeric antigen receptor (CAR) targeting specific proteins on cancer cells and then reinfusing them into the body.

Gene Therapy 69

Gene Therapy Gene Clinical Trials Clinical Trials 69

XTalks

DECEMBER 24, 2020

The pandemic propelled the life science and healthcare sectors onto center stage, and they rose to the occasion against the most unprecedented health challenge in recent times. While COVID-19 has undoubtedly been the biggest story in the life science industry in 2020, it was a busy and positive year in many other areas.

Life Science 111

Life Science Vaccination Vaccine Gene 111

XTalks

FEBRUARY 5, 2024

In the dynamic landscape of oncology therapeutics, understanding the trends and performances of leading drugs is crucial for stakeholders across the healthcare and life sciences sectors. The top 40 best-selling oncology drugs in 2023, informed by 2022 sales statistics, mark significant milestones in cancer treatment and research.

FDA Approval 52

FDA Approval Drugs Sales Development 52

Roots Analysis

JANUARY 28, 2024

With her commitment to staying at the forefront of the healthcare and life sciences domain, she is able to effectively analyze complex datasets and provide actionable insights. Throughout her career, Jayita has contributed to over six syndicate market research reports, covering a wide range of trending domains.

Big Data 40

Big Data Medicine Marketing Clinical Trials 40

XTalks

FEBRUARY 11, 2021

For example, British scientist Rosalind Franklin gained recognition for her work after her death, which is not unheard of, but with it came the revelation that her work, which helped demonstrate the double helical structure of DNA, went largely uncredited by famed DNA duo James Watson and Francis Crick.

Genetics 119

Genetics DNA Genomics Genome 119

XTalks

MAY 17, 2024

The PrEPVacc Trial The innovative PrEPVacc trial in Eastern and Southern Africa investigated two separate experimental vaccine regimens — a DNA vaccine combined with a protein-based vaccine and a combined DNA, MVA and protein-based vaccine — and a new form of pre-exposure prophylaxis (PrEP).

Vaccination 52

Vaccination Vaccine Research Immune Response 52

XTalks

MAY 12, 2022

The detergent will denature the proteins and result in the release of the viral genomic DNA. The developed primers or the capture oligonucleotides will target and bind to the viral DNA and thus, they will form a hybrid called an amplicon.

In-Vitro 52

In-Vitro DNA Development Genomics 52

XTalks

FEBRUARY 3, 2021

Biotech company Novavax (Nasdaq: NVAX ) reported that its protein-based vaccine demonstrated an efficacy of 89.3 Johnson & Johnson’s single-shot DNA vaccine candidate was shown to have an overall effectiveness of 66 percent in preventing moderate to severe COVID-19. Novavax’s Protein Vaccine.

Vaccination 103

Vaccination Vaccine Trials Protein 103

Pharmaceutical Technology

JUNE 21, 2023

Life sciences venture capital firm Flagship Pioneering has unveiled Empress Therapeutics, a small molecule drug development startup. These span multiple structural classes and target several classes of proteins, including cytokines, enzymes, G protein-coupled receptors (GPCRs), and ion channels.

Development 130

Development Drugs Protein Life Science 130