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Dr. Stanley Plotkin , Professor Emeritus at The Wistar Institute, said, “INOVIO’s DNA vaccine appeared to be quite safe with few significant reactions but yet induced both antibody and T cell responses to SARS-CoV-2.”
About INOVIO’s DNA Medicines Platform.
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This technology, which allows for precise editing of DNA at specific locations, has been a major focus in the field due to its potential to directly target and modify cancer-causing genes. As of October 19, 2023, there were 692 FDA-approved devices linked to AI/ML , underscoring the expanding role of these technologies in healthcare.
When alpha-emitting radionuclides are delivered to cancer cells, the emitted alpha particles cause substantial damage to the DNA of the cells, leading to cell death. Advantages of Alpha Emitter Therapy Over the past two decades, the radiological and chemical properties of alpha emitting isotopes have regained prominence in medical physics.
Liquid biopsy tests in oncology involve isolating entities such as circulating tumor cells (CTC), circulating tumor DNA (ctDNA) and tumor-derived exosomes. The cfDNA that originates from tumors is called circulating tumor DNA (ctDNA). These tumor-derived entities are used to derive genomic and proteomic data.
The T cell test from Adaptive Biotechnologies detects DNA sequences from T cells, specifically sequencing T cell receptors (TCR) on CD8+ T cells. Detection of specific T cell populations against SARS-CoV-2 is thus useful in the detection of infection and determining long-term immunity.
In this case, Delfi is developing a highly sensitive and specific assay intended for comprehensive and cost-effective distribution and adoption by utilizing an advanced machine learning algorithm to the circulating DNA fragment patterns, which can be evaluated through low-cost sequencing.
ctDNA: New data was presented demonstrating major advances in the understanding of circulating tumor DNA (ctDNA). What I’ve really noticed is all the research and advances that we’ve seen with circulating tumor DNA or CT DNA, there’s been great advances. This is Pharmaphorum web editor Nicole Raleigh. And that’s something new.
Unlike COVID-19 tests that need to be processed through PCR machines, the new rapid test is processed through a handheld DNA analyzer. Meanwhile, Health Canada has given approval to Spartan Biosciences to start shipping its new rapid test for COVID-19 to federal and provincial governments immediately. Drugs and Vaccines.
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