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This Common Artificial Sweetener Can Break Down DNA, Scientists Warn

AuroBlog - Aurous Healthcare Clinical Trials blog

The artificial sweetener sucralose (marketed as Splenda) is widely used and found in products like diet soda and chewing gum. According to a new study, it’s also capable of damaging the DNA material inside our cells.

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Leading innovators in DNA polymerase compositions for the pharmaceutical industry

Pharmaceutical Technology

In the last three years alone, there have been over 633,000 patents filed and granted in the pharmaceutical industry, according to GlobalData’s report on Innovation in Pharmaceuticals: DNA polymerase compositions. The majority of DNA replication is performed by Pol δ and Pol ε.

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DNA sequencer Element Bio raises $277m to take on Illumina

pharmaphorum

Element Bio’s bid to take on Illumina in the DNA sequencing market has been helped by an impressive $277m financing round

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Boundless Bio raises $100m as IPO market rouses

Pharmaceutical Technology

Boundless has two assets in clinical trials targeting extrachromosomal DNA in cancer patients.

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Merck KGaA signs DNA damage response cancer deal with Artios Pharma

pharmaphorum

Germany’s Merck KGaA has joined with UK-based Artios Pharma in a potential multi-billion dollar deal to investigate novel DNA damage response targets in cancer. The principle of DNA damage response is already being exploited by AstraZeneca and other companies with their poly (ADP-ribose) polymerase (PARP) inhibitor drugs.

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Pfizer drops the blue pill, kicks off 2021 with new DNA logo

pharmaphorum

Pharma companies are always talking about moving ‘beyond the pill’, and Pfizer’s new brand identity embodies that – it’s decades old pill-like logo has been replaced with a DNA double helix that it says reflects its commitment to breakthrough science. Encoded within a successful emblem is a company’s DNA – its history, its future.

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COVID prompts another milestone, as India clears first DNA vaccine

pharmaphorum

The COVID-19 pandemic accelerated the development of mRNA-based vaccines, and its influence has now extended to DNA-based shots as well, with Zydus Cadila’s ZyCoV-D getting emergency use authorisation in India. Proponents of the approach claim that DNA vaccines may have advantages over other technologies like mRNA.

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