pharmaphorum

SEPTEMBER 14, 2020

Here he gives us a deeper look at how genomic medicine is evolving and the barriers that are preventing it from reaching its full potential. At that time, we thought this would be the holy grail for medicine. Now, however, the field is changing with respect to genomic medicine. This allows for much lengthier reads.

Genomics 119

Genomics Genome Medicine Gene 119

XTalks

FEBRUARY 12, 2024

The ad pays homage to notable scientists throughout the times and also celebrates 175 years of Pfizer’s contributions to scientific innovation. In 2023, alone, the company said its medicines and vaccines reached more than 1.3 There is a longer 90-second version of the ad from which the ad is cut from.

Scientist 105

Scientist DNA Vaccine Vaccination 105

STAT News

JANUARY 16, 2023

But bits of tumor DNA adrift in a patient’s blood are an important bellwether for whether cancer will return — and, as a new study shows, can predict which treatments are likely to work. They’re far too small to be seen by even the most sophisticated medical imaging device.

DNA 111

DNA Scientist Medicine Research 111

Scienmag

JULY 12, 2021

USC researchers have achieved a better way to identify elusive DNA variants responsible for genetic changes affecting cell functions and diseases. Using computational biology tools, scientists at the university’s Dornsife College of Letters, Arts and Sciences studied “variable-number tandem repeats” (VNTR) in DNA.

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DNA Research Genetics Scientist 69

Scienmag

APRIL 1, 2021

Salk scientists reveal new insights into neurodegenerative disorders and potential for genetic therapies Credit: Salk Institute/Waitt Advanced Biophotonics Center LA JOLLA–(April 1, 2021) Neurons lack the ability to replicate their DNA, so they’re constantly working to repair damage to their genome.

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DNA Genome Genomics Genetics 77

Scienmag

JANUARY 12, 2022

Pacific time to coincide with the study’s publication in The New England Journal of Medicine Media contact: Hanae Armitage at (650) 725-5376 (harmitag@stanford.edu) Fastest DNA sequencing technique helps undiagnosed patients find answers in mere hours A new ultra-rapid genome sequencing approach developed by Stanford Medicine scientists and their collaborators (..)

DNA 62

DNA Genome Genomics Scientist 62

Scienmag

APRIL 15, 2021

Team of Japanese and European scientists identify a novel genetic mitochondrial disorder by analyzing DNA samples from three distinct families Credit: Fujita Health University DNA ligase proteins, which facilitate the formation of bonds between separate strands of DNA, play critical roles in the replication and maintenance of DNA.

Genetics 105

Genetics DNA Genome Genomics 105

Scienmag

MAY 6, 2021

Jude Children’s Research Hospital scientists have developed a highly efficient method to address a major challenge in biology–identifying the genetic ‘switches’ that regulate gene expression. Credit: St. Jude Children’s Research Hospital St.

Gene Expression 97

Gene Expression Regulation Gene DNA 97

Scienmag

JULY 21, 2022

University of Virginia School of Medicine researchers have created an important new resource to provide a better look at how genes in specific cells contribute to the risk of coronary artery disease, a leading cause of death worldwide.

DNA 79

DNA Genome Genomics Gene 79

STAT News

OCTOBER 12, 2022

The scientist flicked on a laser, filling the rat’s brain with blue light. From the outside, this would appear to be a pretty run-of-the-mill neuroscience experiment, except for the fact that the neurons directing the rat to its thirst-quenching reward didn’t contain any rat DNA.

DNA 144

DNA Containment Scientist Medicine 144

Scienmag

MARCH 21, 2022

Wilmington, DE, (MARCH 21, 2022) – A new study from scientists at ChristianaCare’s Gene Editing Institute is advancing the safety and efficacy of using CRISPR gene editing in patient treatments by demonstrating how to identify and evaluate the broad-based biological impact of gene editing on targeted tissues, where the edits are designed to fully disable (..)

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Gene Editing Gene Scientist DNA 80

Scienmag

MAY 2, 2022

WINSTON-SALEM, NC – May 2, 2022 — Wake Forest Institute for Regenerative Medicine (WFIRM) scientists working on CRISPR/Cas9-mediated gene editing technology have developed a method to increase efficiency of editing while minimizing DNA deletion sizes, a key step toward developing gene editing therapies to treat genetic diseases.

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Gene Editing DNA Gene Development 58

Scienmag

APRIL 27, 2022

CHAPEL HILL, NC – Inside embryonic cells, specific proteins control the rate at which genetic information is transcribed from DNA to messenger RNA – a crucial regulatory step before proteins are created. Then, organs develop and hopefully function properly.

Scientist 83

Scientist Gene RNA Protein 83

STAT News

OCTOBER 5, 2022

Scientists rely on gene synthesis technologies as a research tool for everything from basic research to vaccine development and drug target identification. Ever since the inception of gene synthesis, there have been concerns about possible misuse of synthetic genes. Read the rest…

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Gene DNA Engineer Scientist 98

Medical Xpress

DECEMBER 15, 2022

Northwestern Medicine scientists have identified disease-causing DNA variants in two genes linked to neurodevelopmental deficits including microcephaly in children, according to findings published in Nature Communications.

Gene 75

Gene DNA Scientist Medicine 75

Medical Xpress

FEBRUARY 21, 2023

Northwestern Medicine scientists have identified a gene that plays a role in cellular responses to molecular stressors, such as DNA damage and nutrient scarcity, according to findings published in Nature Communications.

Gene 75

Gene DNA Scientist Medicine 75

STAT News

MARCH 9, 2023

LONDON — Scientists at this year’s genome editing summit spent Tuesday showing the world just how far CRISPR -based medicines for treating human diseases have come in a decade. Continue to STAT+ to read the full story…

Gene Editing 98

Gene Editing Genome Genomics DNA 98

Scienmag

OCTOBER 22, 2020

For scientists, digging into feces provides insights into animal diets and is particularly useful for understanding nocturnal or rare species. When animals eat, prey DNA travels all the way through animal digestive tracts and comes out again. Credit: Illustration by Amy Koehler Poop is full of secrets.

DNA 54

DNA Containment Scientist Bioinformatics 54

Scienmag

MAY 28, 2021

The scientists analyzed short fragments of tumor DNA that are circulating in the blood. Credit: Tatjana Hirschmugl A new study exploits the characteristic epigenetic signatures of childhood tumors to detect, classify and monitor the disease.

DNA 96

DNA Genetics Scientist Clinical Trials 96

STAT News

JULY 28, 2022

In a little-noticed study published earlier this year, scientists from Oregon Health & Science University reported the birth of three mouse pups that had been created with a never-before-used recipe for reproduction.

In-Vitro 98

In-Vitro Research DNA Genetics 98

Scienmag

OCTOBER 13, 2021

LA JOLLA—(October 13, 2021) For the past fifteen years, cancer researchers have been using DNA sequencing technology to identify the gene mutations that cause the different forms of cancer.

Scientist 52

Scientist Gene DNA Genetics 52

BioTech 365

APRIL 19, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: DNA robots designed in minutes instead of days.Someday, scientists believe, tiny DNA-based robots and other nanodevices will deliver medicine inside our bodies, detect the presence of deadly … Continue reading →

DNA 40

DNA Scientist Medicine Research 40

Scienmag

DECEMBER 8, 2020

Credit: Kim Ratliff, Production Coordinator, Augusta University A key way radiation therapy and chemotherapy work is by making highly lethal double-strand breaks in the DNA of cancer cells.

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Protein DNA Scientist Production 76

The Pharma Data

FEBRUARY 22, 2022

State-of-the-art facility will headquarter research efforts in Boston and New York to accelerate the development of RNA and DNA-based medicines. Adams, vice president of genetic medicine at Lilly and co-director of the Institute. ” The Institute will be headquartered in 334,000 sq.

Genetics 52

Genetics Medicine RNA Scientist 52

pharmaphorum

OCTOBER 7, 2020

Originally discovered in bacteria as a defense mechanism against pathogens, CRISP/Cas9 has made it possible to make exquisitely detailed and precise alterations to DNA sequences on demand, and as a tool for molecular biology has already transformed research into diseases and drug discovery. million) Nobel Prize award. “In

Gene Editing 105

Gene Editing Bacteria DNA Gene 105

Scienmag

APRIL 8, 2021

Credit: IRB Barcelona In cancer, personalised medicine takes advantage of the unique genetic changes in an individual tumour to find its vulnerabilities and fight it. Many tumours have a higher number of mutations due to a antiviral defence mechanism, the APOBEC system, which can accidentally damage DNA and cause mutations.

Scientist 53

Scientist DNA Genetics Medicine 53

The Pharma Data

NOVEMBER 17, 2021

Mount Sinai researchers have developed a new model that uses DNA and RNA sequencing data from hundreds of patients to identify specific genes and genetic alterations responsible for never-before-defined subtypes of a blood cancer called multiple myeloma.

Scientist 52

Scientist RNA DNA Genetics 52

Scienmag

DECEMBER 29, 2020

Method will help researchers better understand mitochondrial DNA diseases LOS ANGELES — Scientists from the UCLA Jonsson Comprehensive Cancer Center have developed a simple, high-throughput method for transferring isolated mitochondria and their associated mitochondrial DNA into mammalian cells.

Scientist 40

Scientist Development DNA Genetics 40

Scienmag

FEBRUARY 11, 2021

11, 2020 -Scientists have developed an affordable, downloadable app that scans for potential unintended mistakes when CRISPR is used to repair mutations that cause disease. The app reveals potentially risky DNA […].

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Gene Gene Therapy DNA Scientist 73

Scienmag

JANUARY 12, 2021

Researchers have found a simple way to eliminate almost all sequencing errors produced by a widely used portable DNA sequencer, potentially enabling scientists working outside the lab to study and track microorganisms like the SARS-CoV-2 virus more efficiently.

DNA 40

DNA Scientist Research Bioinformatics 40

XTalks

OCTOBER 8, 2024

The 2024 Nobel Prize in Physiology or Medicine has been awarded to American scientists Victor Ambros and Gary Ruvkun for their groundbreaking discovery of microRNA (or miRNA) and its role in post-transcriptional gene regulation. A gene contains instructions within our DNA.

Regulation 52

Regulation Genetics Scientist RNA 52

Pharmaceutical Technology

JUNE 30, 2022

Earlier this month, scientists from Cambridge University and the Madrid-based National Cancer Research Center described a novel framework tracking chromosomal instability and copy number changes in particularly deadly cancers. At the same time, other patterns are more recent and unique to the cancer cell, he adds.

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Genome Project Genomics Genome DNA 130

The Pharma Data

SEPTEMBER 14, 2020

One of the biggest game-changing advancements in cancer care came about 20 years ago when researchers learned that they could create medicines that selectively jam up cancer’s growth machinery without damaging the rest of the body. Today these medicines, called targeted therapies, are available for treating many forms of cancer.

Medicine 52

Medicine Clinical Trials Clinical Trials Trials 52

Scienmag

MAY 10, 2021

Scientists have made major advances in understanding and developing treatments for many cancers by identifying genetic mutations that drive the disease.

DNA 50

DNA Genome Genomics Genetics 50

pharmaphorum

FEBRUARY 3, 2021

Dr Jennifer Harbottle, senior scientist in the R&D Base Editing team of PerkinElmer’s Horizon Discovery business, looks at progress made in the realms of biotechnology and next-generation diagnostics, vaccines and therapeutics, including the application of CRISPR-Cas9 gene editing in developing and refining cell therapies.

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Gene Editing Gene DNA Engineer 98

STAT News

NOVEMBER 4, 2022

By 2019, his brother had assembled a team of scientists at Charles River Laboratories, UMass Chan Medical School, Yale University, and other institutions to help design a bespoke therapy for Terry. Many scientists hope that the approach proves to be a safer alternative to gene editing therapies that make permanent changes to DNA itself.

Gene Editing 105

Gene Editing Gene Gene Therapy Scientist 105

pharmaphorum

DECEMBER 21, 2020

Compared with many of the established names in pharma these companies are young upstarts but they have managed to achieve what other big names in the industry have failed to do and harness the power of mRNA to make medicine. They are very good doctors, scientists and entrepreneurs. I was intrigued by the personalities of the founders.

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Vaccine Vaccination Doctor Doctors 111