Scienmag

NOVEMBER 14, 2021

In a study with lab-grown mouse cells, Johns Hopkins Medicine researchers say they have found that a protein that helps form a structural network under the surface of the cell’s “command center” — its nucleus — is key to ensuring that DNA inside it remains orderly.

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DNA Protein Medicine Research 79

Medical Xpress

FEBRUARY 7, 2023

University of Saskatchewan (USask) College of Medicine graduate student Ananna Arna dedicated a research project to examine how genetics and DNA replication play a role in leukemia development. Of that 7,000, it is estimated that nearly half will face mortality.

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DNA Protein Genetics Medicine 75

Scienmag

SEPTEMBER 28, 2020

Brazilian research group shows that valproic acid (VPA), used to treat epilepsy since the 1960s, modulates gene expression in tumor gene models and acts on DNA conformation and the histones in chromatin Results of recent studies involving valproic acid, used for decades as an anti-convulsant drug, show that it can interact with the conformation of (..)

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DNA Gene Expression Protein Gene 70

Scienmag

MAY 18, 2022

A research team from Carnegie Mellon University and Columbia have combined two emerging imaging technologies to better view a wide range of biomolecules, including proteins, lipids and DNA, at the nanoscale. Credit: Carnegie Mellon University A research team […].

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Scienmag

OCTOBER 13, 2020

A research team from Cologne has discovered that a change in the DNA structure – more precisely in the chromatin – plays a decisive role in the recovery phase after DNA damage. The key is a double occupation by two methyl groups on the DNA packaging protein histone H3 (H3K4me2).

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DNA Genomics Genome Research 72

BioTech 365

JULY 23, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Researchers discover that protein switches functions to regulate DNA replication.One protein. One mechanism of action. Two biologically opposite effects.

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DNA Protein Regulation Research 40

Roots Analysis

DECEMBER 12, 2021

DNA data storage involves encoding and decoding binary data to and from synthesized strands of DNA. DNA data storage is an innovative technology that works by encoding large digital data sequences of binary form (0s and 1s) into DNA sequences (Adenine (A), Guanine (G), Cytosine (C) and Thymine (T)). DNA Storage.

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DNA Research Engineer Marketing 52

Scienmag

AUGUST 20, 2020

Some of these structures, such as those found in DNA, RNA and proteins, are formed through complex molecular interactions that are not easily duplicated by inorganic materials. A research team led by Richard Robinson, associate professor of materials science and engineering, discovered a […].

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Research RNA DNA Engineer 75

Pharmaceutical Technology

FEBRUARY 23, 2023

Within the emerging innovation stage, DNA chips, tissue culturing automation, and mass spectrometry analysis are disruptive technologies that are in the early stages of application and should be tracked closely. Codexis, a protein engineering company, is the leading patent filer.

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Drugs DNA In-Vivo In-Vitro 189

Scienmag

SEPTEMBER 10, 2020

Led by Qi Zhang and Robert McGinty, UNC-Chapel Hill scientists used cryo-electron microscopy technology to produce the first-ever high-resolution structure of the protein cGAS bound to the DNA packaging unit inside human cell nuclei Credit: UNC-Chapel Hill CHAPEL HILL, NC – September 10, 2020 – UNC-Chapel Hill researchers have, for the (..)

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Medical Xpress

DECEMBER 27, 2022

Anthracyclines—such as doxorubicin, frequently used against breast cancer—kill cancer cells by damaging their DNA. Anthracyclines are a class of chemotherapies effective in treating many forms of cancer, including leukemias, lymphomas and breast cancer.

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Protein DNA Research 75

BioTech 365

MARCH 10, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Sharing shears: Conserved protein segment activates molecular DNA scissors for DNA repair.Scientists at Tokyo Institute of Technology (Tokyo Tech) have uncovered mechanisms underlying the activation of the … Continue reading (..)

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DNA Protein Research 40

Pharmaceutical Technology

JUNE 23, 2022

Researchers at the University of New Hampshire (UNH) have found that a repurposed drug, CCG-50014, could hinder the activity of a key enzyme of the SARS-CoV-2 virus, which causes Covid-19. Mpro has become the main focus of intense research and treatment development as it is vital for viral replication.

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Worldwide Clinical Trials

AUGUST 14, 2024

Protein-based Biomarkers : Include proteins found in blood, tissues, or other bodily fluids that can indicate disease presence or progression. Protein-based biomarkers are the most widely used biomarkers in cancer screening and diagnosis. Biomarker data interpretation can be difficult, particularly for oncology studies.

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Genetics Protein Gene Genotype 195

Scienmag

FEBRUARY 12, 2021

Research offers new lead for cancer drug discovery Credit: Rensselaer Polytechnic Institute TROY, N.Y. — An antioxidant found in green tea may increase levels of p53, a natural anti-cancer protein, known as the “guardian of the genome” for its ability to repair DNA damage or destroy cancerous cells.

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Genomics Genome DNA Protein 98

Pharmaceutical Technology

MARCH 10, 2023

In the past, researchers have often had to seek help from outside the UK, thus delaying clinical trials and patient access. The strategy , underlines one of the government’s goals of increasing the UK’s manufacturing capacity for DNA-based therapeutics. The NHSBT hopes the CBC will increase the UK’s competitiveness within the market.

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Gene Therapy Manufacturing Gene Clinical Trials 264

Pharmaceutical Technology

DECEMBER 7, 2022

Alongside the discourse on what the positive study results could mean for patients, researchers are prioritising the development of more biomarkers to identify potential responders and improve patient outcomes. Further research into dementia biomarkers. Amyloid-targeting therapies. At CTAD, one abstract (no.

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Development Drugs Clinical Trials Clinical Trials 264

Scienmag

OCTOBER 13, 2020

Researchers find that simple DNA-peptide interactions create a surprising diversity of compartmentalised higher-ordered phase behaviours, suggesting that these polymers’ primordial interactions helped create modern complex biological structures.

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DNA Containment Protein Research 52

Scienmag

JUNE 13, 2022

The legible sections contained the code for making cell proteins; the other regions, representing about 90% of the entire genome, were dismissed as “junk DNA,” […].

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Genome Genomics DNA Containment 77

Scienmag

JANUARY 28, 2022

A protein that masterminds the way DNA is wrapped within chromosomes has a major role in the healthy functioning of blood stem cells, which produce all blood cells in the body, according to a new study from researchers at Weill Cornell Medicine. The protein, known as histone H3.3,

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Regulation DNA Research Development 57

Roots Analysis

JUNE 1, 2022

DNA cloning is the field of synthetic biology which can be helpful to understand the effect of mutation on a particular gene. Many diseases that can be treated using DNA cloning, such as leukemia and sickle cell anemia, involving the replacement of defected gene. DNA Cloning Kit Providers – Current Market Landscape.

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DNA Genetics Reagent Marketing 52

BioTech 365

JANUARY 17, 2022

Targeted Immunotherapy in Oncology Market Research Report 2021: Development of New Targeted Immunotherapies, Particularly Those that Deliver Therapeutic DNA and Proteins – ResearchAndMarkets.com Targeted Immunotherapy in Oncology Market Research Report 2021: Development of New Targeted Immunotherapies, Particularly Those that Deliver … (..)

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DNA Protein Marketing Development 40

Medical Xpress

DECEMBER 13, 2024

Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, have discovered how a protein called lamin A helps repair the protective barrier around a cell's DNA.

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DNA Genetics Life Science Protein 52

Pharmaceutical Technology

DECEMBER 7, 2022

Alongside the discourse on what the positive study results could mean for patients, researchers are prioritising the development of more biomarkers to identify potential responders and improve patient outcomes. Further research into dementia biomarkers. Amyloid-targeting therapies. At CTAD, one abstract (no.

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Development Drugs Clinical Trials Clinical Trials 246

BioTech 365

JUNE 9, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Study reveals structural changes of a key protein involved in DNA repair.Researchers of the University of Oulu, Finland, have for the first time uncovered the molecular structure … Continue reading →

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DNA Protein Research 40

BioTech 365

JUNE 25, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: MeCP2: A binding protein that prevents DNA from being wrapped up in nucleosomes.A

DNA 40

DNA Protein Genetics Research 40

BioTech 365

SEPTEMBER 21, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Regulator proteins or symphonies of genes: Statistical modeling points way toward unified theory for DNA folding.At

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DNA Regulation Protein Gene 40

BioTech 365

AUGUST 2, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Atomic-level, 3-D structure of MUTYH protein opens small window into DNA repair mechanism.Researchers have analyzed the three-dimensional structure of a protein that suppresses the development of colorectal … Continue reading (..)

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DNA Protein Development Research 40

Pharmaceutical Technology

SEPTEMBER 7, 2022

It is a single-stage, single-use chromatographic purification solution designed for use in manufacturing recombinant protein therapeutics. It removes the need for centrifugation and depth filtration processes to purify proteins more efficiently, turning multiple stages into one. hiking interactions on Protein A capture column’.

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Protein Production DNA Manufacturing 130

Pharmaceutical Technology

MARCH 8, 2023

Molecular science and technology firm Caris Life Sciences and Incyte have entered a strategic research collaboration to advance the latter’s oncology pipeline. The post Caris signs research partnership with Incyte for oncology pipeline appeared first on Pharmaceutical Technology. Please check your email to download the Whitepaper.

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Research Clinical Trials Clinical Trials Life Science 130

Scienmag

JANUARY 11, 2022

Enhancers are regions of DNA that do not code for proteins, but control how genes are expressed. Jude Children’s Research Hospital studied the Vsx2 super-enhancer and its role in the development of the retina. Super-enhancers are clusters of enhancers that together regulate genes with important roles in cell identity.

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Development DNA Gene Protein 80

Scienmag

NOVEMBER 20, 2020

The four-part series kicks off today Skokie, IL – The International Society for Stem Cell Research (ISSCR) is hosting a four-part digital meeting series, Chromatin, Epigenetics, and Nuclear Architecture in Stem Cells, featuring a global line-up of speakers discussing chromatin, the fundamental unit of life.

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DNA Protein Research Genetics 75

BioTech 365

OCTOBER 21, 2020

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Transcription factors may inadvertently lock in DNA mistakes.Transcription factor proteins are the light switches of the human genome.

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DNA Genome Genomics Protein 40

Pharmaceutical Technology

FEBRUARY 15, 2023

Within the emerging innovation stage, cell therapy for ocular disorders, coronavirus vaccine components, and DNA polymerase compositions are disruptive technologies that are in the early stages of application and should be tracked closely. The structural proteins include the capsid, pre-membrane/membrane proteins and envelope (E) proteins.

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Vaccination Vaccine Protein Immune Response 130

BioTech 365

MAY 7, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Study describes new mechanism for terminating transcription of DNA into RNA in bacteria.A bacterial protein helps to stop transcription—the process of making RNA copies of DNA to … Continue reading →

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RNA DNA Bacteria Protein 40

Scienmag

MARCH 15, 2021

The first vaccine has been administered in a comparative adjuvant trial of DNA prime/protein boost HIV vaccine regimens in Kericho, Kenya Credit: U.S. Military HIV Research Program SILVER SPRING, Md.

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Vaccination Vaccine Trials DNA 68

BioTech 365

JULY 13, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: The path(way) less traveled in DNA double-strand break repair.BRCA1, a protein that is well-known for its role in hereditary breast cancer, is an important part of the … Continue reading →

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