Scienmag

JUNE 11, 2021

In a discovery that challenges long-held dogma in biology, researchers show that mammalian cells can convert RNA sequences back into DNA, a feat more common in viruses than eukaryotic cells PHILADELPHIA – Cells contain machinery that duplicates DNA into a new set that goes into a newly formed cell.

DNA 58

DNA RNA Containment Research 58

Drug Discovery World podcast

MARCH 13, 2025

They are called: Open science, genomics, and the quiet revolution in our approach to pharma and Junk DNA: How the dark genome is changing RNA therapies . In the first article, Evan Floden, CEO of Seqera Labs, examines how data sharing platforms are impacting cancer and genomics research.

Genome 52

Genome Genomics RNA DNA 52

Pharmaceutical Technology

MARCH 28, 2023

The gene-editing technology allows for precise, directed changes to genomic DNA. It edits genes by precisely cutting DNA, then allowing natural DNA repair processes to take over. The system comprises the Cas9 enzyme and a guide RNA.

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Gene Editing DNA Gene Gene Therapy 235

Roots Analysis

AUGUST 17, 2023

Genome sequencing has historically been classified into DNA sequencing and RNA sequencing. DNA sequencing generates data that is very robust, reproducible, insightful, and can be applied to genes having different expression level by selecting genomic region. between 2022 and 2035.

RNA 52

RNA DNA Genome Genomics 52

Scienmag

AUGUST 20, 2020

Some of these structures, such as those found in DNA, RNA and proteins, are formed through complex molecular interactions that are not easily duplicated by inorganic materials. A research team led by Richard Robinson, associate professor of materials science and engineering, discovered a […].

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Research RNA DNA Engineer 75

Scienmag

DECEMBER 16, 2020

New research from the Whitehead Institute suggests that the products of transcription — RNA molecules — regulate their own production through a feedback loop Credit: Jon Henninger/Whitehead Institute At any given moment in the human body, in about 30 trillion cells, DNA is being “read” into molecules of messenger RNA, the intermediary (..)

RNA 52

RNA DNA Regulation Production 52

BioTech 365

MAY 7, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Study describes new mechanism for terminating transcription of DNA into RNA in bacteria.A

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RNA DNA Bacteria Protein 40

Scienmag

APRIL 20, 2021

This can result in patchy data that fall short of what researchers need to anticipate and address outbreaks. Real-world disease and parasite monitoring is often hampered by the inability of traditional approaches to easily sample broad geographical areas and large numbers of individuals.

RNA 72

RNA DNA Research Bioinformatics 72

Pharmaceutical Technology

APRIL 24, 2023

Robert Langer was part of the first cohort of researchers to begin nanoparticle research , as his lab at Cornell University developed tiny particles to deliver large molecules for angiogenesis. The next wave came from early research into liposomes and lipid nanoparticles, both of which are used for drug delivery.

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Drug Delivery Vaccination Vaccine Research 147

Pharmaceutical Commerce

AUGUST 14, 2024

The facility will focus on furthering RNA and DNA-based therapies.

RNA 52

RNA DNA Development Research 52

XTalks

AUGUST 29, 2022

Viral vectors have traditionally been used in gene editing where the shells of viruses carry the template DNA into cells, but this method has its disadvantages. However, researchers are determined to overcome this hurdle. In cells, DNA exists as both single and double strands, and Cas9 specifically attaches to double-stranded DNA.

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Gene Editing DNA Gene Genome 98

XTalks

AUGUST 10, 2021

The test was developed by researchers at the Wyss Institute for Biologically Inspired Engineering at Harvard University, the Massachusetts Institute of Technology (MIT) and several Boston area hospitals. The researchers published the details of the device in a paper in Science Advances.

RNA 105

RNA Containment DNA Engineer 105

BioTech 365

JANUARY 22, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Regulating the ribosomal RNA production line.The enzyme that makes RNA from a DNA template is altered to slow the production of ribosomal RNA (rRNA), the most abundant … Continue reading →

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RNA Regulation Production DNA 40

Pharmaceutical Technology

MARCH 8, 2023

Molecular science and technology firm Caris Life Sciences and Incyte have entered a strategic research collaboration to advance the latter’s oncology pipeline. The post Caris signs research partnership with Incyte for oncology pipeline appeared first on Pharmaceutical Technology. Please check your email to download the Whitepaper.

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Research Clinical Trials Clinical Trials Life Science 130

XTalks

JANUARY 21, 2025

The Shield test provides a non-invasive approach to colorectal cancer screening by analyzing blood for key DNA changes linked to cancer. There, plasma is separated, and tumor DNA is identified by detecting genetic mutations, methylation patterns and fragmentation signals. The Onclarity HPV reagent pack extraction combo.

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FDA Approval Manufacturing Development RNA 105

Pharmaceutical Technology

JUNE 23, 2022

Researchers at the University of New Hampshire (UNH) have found that a repurposed drug, CCG-50014, could hinder the activity of a key enzyme of the SARS-CoV-2 virus, which causes Covid-19. Mpro has become the main focus of intense research and treatment development as it is vital for viral replication.

Drugs 130

Drugs Protein Genome Genomics 130

Medical Xpress

FEBRUARY 2, 2023

Researchers at the Hong Kong University of Science and Technology (HKUST) developed a novel technology which allows genomic DNA and RNA sequencing to be carried out simultaneously in single cells of both frozen and fresh tissues, and identified rare brain tumor cell "spies" disguised as normal cells with this method.

RNA 72

RNA DNA Genome Genomics 72

Scienmag

OCTOBER 7, 2020

Computational algorithms enable identification and optimization of RNA-based tools for myriad applications DNA and RNA have been compared to “instruction manuals” containing the information needed for living “machines” to operate.

RNA 69

RNA DNA Containment Bioinformatics 69

Pharmaceutical Technology

FEBRUARY 23, 2023

Moderna has entered a strategic research and development partnership with ElevateBio’s Life Edit Therapeutics to discover and develop new in-vivo mRNA gene editing therapies. Under the deal, both companies will partner on the research and preclinical studies, which will be funded by Moderna.

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Gene Editing Gene In-Vivo Gene Therapy 147

Worldwide Clinical Trials

AUGUST 14, 2024

Molecular Biomarkers : Encompass various molecules, such as RNA and metabolites, to reflect the physiological state of the cells and their disease pathways. Recent Advancements in Biomarker Research The latest advancements in biomarker research have further elevated the biomarker’s role in disease diagnosis, treatment, and monitoring.

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Genetics Protein Gene Genotype 195

XTalks

APRIL 6, 2022

Lung cancer is the most common cancer in men and the third most common cancer in women, according to global lung cancer statistics by the World Cancer Research Fund. Cancerous cells and tumors release small fragments of DNA into the bloodstream called circulating tumour DNA (ctDNA).

DNA 105

DNA In-Vitro Doctors Doctor 105

pharmaphorum

OCTOBER 31, 2022

VRG50635 was discovered using Verge’s AI-powered discovery platform ConVERGE which maps out the biological underpinnings of diseases using data on DNA, RNA and protein profiles to identify new targets and drug that can interact with them.

Genome 136

Genome Genomics Drugs RNA 136

XTalks

AUGUST 9, 2022

The test achieves its speed in two ways: a new RNA to DNA conversion step designed by Dr. Dafforn and his research team that avoids reverse transcription, and an alternative DNA amplification process (EXPAR). This makes EXPAR an even faster DNA amplification technique than not only PCR but also LAMP.”.

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Licensing Licensing DNA RNA 98

Scienmag

MAY 27, 2021

Capturing how RNA polymerase enzymes kick off transcription On scales too small for our eyes to see, the business of life happens through the making of proteins, which impart to our cells both structure and function.

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Gene Expression RNA DNA Protein 41

The Pharma Data

NOVEMBER 17, 2021

Mount Sinai researchers have developed a new model that uses DNA and RNA sequencing data from hundreds of patients to identify specific genes and genetic alterations responsible for never-before-defined subtypes of a blood cancer called multiple myeloma.

Scientist 52

Scientist RNA DNA Genetics 52

Pharmaceutical Technology

FEBRUARY 15, 2023

Within the emerging innovation stage, cell therapy for ocular disorders, coronavirus vaccine components, and DNA polymerase compositions are disruptive technologies that are in the early stages of application and should be tracked closely. The structural proteins include the capsid, pre-membrane/membrane proteins and envelope (E) proteins.

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Vaccination Vaccine Protein Immune Response 130

Roots Analysis

FEBRUARY 23, 2022

NGS has emerged as an evolutionary technology in modern biotechnology and healthcare research, enabling researchers to develop a better understanding of the cause and consequences of disease. During our research, we came across more than 280 NGS library preparation kits, that are presently available in the market.

Genetics 52

Genetics DNA RNA Reagent 52

Roots Analysis

FEBRUARY 21, 2022

Advancement in DNA sequencing technologies have resulted in noteworthy developments in various healthcare-related research fields, such as diagnostics and personalized medicine. During our research, we came across more than 55 players, which claim to offer 280+ NGS library preparation kits.

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Marketing Gene Sequencing DNA Genome 52

BioTech 365

FEBRUARY 5, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: At the core of the integrator complex.Gene expression is a highly regulated process that involves several steps. These include transcription of DNA instructions into RNA, removal of … Continue reading →

RNA 40

RNA DNA Regulation Research 40

BioTech 365

APRIL 13, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Scaling up genome editing in tiny worms.Understanding the effects of specific mutations in gene regulatory regions—the sections of DNA and RNA that turn genes on and off—is … Continue reading →

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Genome Genomics RNA DNA 40

The Pharma Data

FEBRUARY 22, 2022

State-of-the-art facility will headquarter research efforts in Boston and New York to accelerate the development of RNA and DNA-based medicines. ” The Institute will be headquartered in 334,000 sq. of leased space in a 12-story building, developed and operated by Alexandria Real Estate Equities, Inc.,

Genetics 52

Genetics Medicine RNA Scientist 52

Worldwide Clinical Trials

JUNE 15, 2022

We’ve also seen a decrease in available research nurses, as they have had to be reassigned to COVID patients. The pandemic has had a lasting impact on the ability of sites to participate in trials, particularly in the US. We’ve seen resignations across the sites we work with, as medical staff seek employment where they can work remotely.

Gene Therapy 130

Gene Therapy Gene Clinical Trials Clinical Trials 130

pharmaphorum

OCTOBER 2, 2020

Vaccibody, which is also entitled to tiered royalties on sales of any marketed products, will develop the DNA-based individualised neoantigen vaccines until the end of phase 1b. Vaccibody has been working on a targeted DNA-based vaccine platform, in a bid to find a potential new treatment paradigm for individualised cancer vaccines.

Vaccination 59

Vaccination Vaccine Immune Response Drugs 59

Roots Analysis

MARCH 16, 2023

Messenger ribonucleic acid (mRNA) is a single-stranded molecule that is complementary to a gene’s DNA. It is important in the process of protein synthesis because mRNA is responsible for transferring genetic information from DNA to ribosomes, which then decodes the genetic information into a protein.

Vaccination 52

Vaccination Vaccine DNA Protein 52

Roots Analysis

AUGUST 12, 2024

Molecular diagnostic tests refer to tests intended to detect specific sequences in human genomic samples, such as DNA or RNA, in order to diagnose a particular disease. The common types of molecular diagnostic tests include PCR, RT-PCR, DNA microarrays and next generation sequencing tests. What are Molecular Diagnostic Tests?

Genetics 40

Genetics Gene Expression RNA DNA 40

The Pharma Data

NOVEMBER 22, 2020

Their research – the first of its kind – suggests that the system can be utilized to address cancer in animals, according to Professor Dan Peer, whose peer-reviewed research was published in the Science Advances journal. Cas-9 represents the Cas9 protein, an enzyme that cuts foreign DNA. ” Source link.

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Gene Editing DNA Genome Genomics 52

The Pharma Data

OCTOBER 19, 2020

Caris’ collaborative network focused on expanding the application of precision medicine in oncology supports Winship’s enterprising approach to research leading to transformative discoveries in cancer care and treatment. IRVING, Texas and ATLANTA , Oct. Winship is one of 32 U.S. Curran, Jr. , FACR, FASCO.

Life Science 52

Life Science Clinical Trials Clinical Trials RNA 52