Scienmag

JANUARY 27, 2021

Credit: John Wallace, VCU Massey Cancer Center Doctors are increasingly using genetic signatures to diagnose diseases and determine the best course of care, but using DNA sequencing and other techniques to detect genomic rearrangements remains costly or limited in capabilities.

DNA 52

DNA Genome Genomics Doctor 52

pharmaphorum

DECEMBER 21, 2021

In a recent webinar held by pharmaphorum, in partnership with IQVIA, a discussion was held looking at how to make academic and commercial medical research more efficient, while also looking at the opportunity of genomic data to bring benefits to patients and healthcare systems. The potential to leverage genomic data.

Development 98

Development Genome Genomics Drugs 98

pharmaphorum

NOVEMBER 3, 2020

Allison’s son David was just six when he started displaying the symptoms of (R)20, a genetic condition that can cause multiple, uncontrollable seizures, declines in cognition and mobility, and terrifying hallucinations. There are no clinical practice guidelines, meaning doctors treat on a case-by-case basis.

Gene Sequencing 118

Gene Sequencing Gene Genome Genomics 118

pharmaphorum

AUGUST 11, 2022

There have been great strides made in genomics to refine tools that determine the safest, most effective course of treatments for patients across a number of disease states. The participants undergo monitoring for genetic variations that could potentially negatively impact their reaction to therapies. About the Author.

Genome 98

Genome Genomics Drugs Genetics 98

XTalks

FEBRUARY 4, 2021

The power of leveraging clinical data to decipher disease mechanisms and fuel drug discovery has rapidly grown in the era of genomics and personalized medicine. Genuity Science focuses on population genomics as a tool to derive novel biological insights through partnerships with industry-leading pharmaceutical and biotech companies.

Research 98

Research Biobanking Drugs Genome 98

XTalks

MAY 20, 2022

Doctors and physicians rely on the results provided by a clinical scientist to make an accurate prognosis, diagnosis and assessment for a patient’s treatment plan. Interpret medical tests and confer with doctors and physicians for a suitable prognosis and treatment plan. Genetic Science. Clinical Pharmaceutical Science.

Scientist 105

Scientist Life Science Clinical Research Doctors 105

pharmaphorum

OCTOBER 6, 2022

By reducing the disease to its key components, a computer-readable network of disease markers was characterised using genetic, biomarker, and clinical data; the model was also populated with ‘disease vs control’ data. He served as Director of the Lowe Family Genomics Core at the Johns Hopkins University from 2005-15.

In-Vivo 98

In-Vivo Research Genetics Drugs 98

Pharmaceutical Technology

FEBRUARY 28, 2023

The vast majority of rare diseases have a genetic cause, with well-known examples including cystic fibrosis, sickle cell disease, Huntingdon’s, and various muscular atrophies and dystrophies. This often puts patients in difficult situations where they are passed between doctors until a correct diagnosis is reached.

Medicine 130

Medicine Marketing Production Drugs 130

Bioengineer

JULY 22, 2021

Geneticists from Trinity College Dublin have discovered how a specific genetic mutation called H3K27M causes a devastating, incurable childhood cancer, known as diffuse midline glioma (DMG), and – in lab studies working with model cell types – successfully reverse its effects to slow cancer cell growth with a targeted drug.

Genetics 52

Genetics Drugs Clinical Trials Clinical Trials 52

The Pharma Data

DECEMBER 17, 2020

Dr. Lisa Forbes — his doctor and co-author of a letter describing his case in the Oct. This patient had a genetic mutation that ruxolitinib is known to work on. Forbes said it’s not clear if other people with type 1 diabetes also have this specific genetic mutation. WEDNESDAY, Oct.

Insulin 52

Insulin Genetics Doctors Doctor 52

pharmaphorum

MARCH 19, 2021

Approximately 85% of rare diseases are genetic, offering significant opportunities to develop better treatments as our understanding of the human genome improves 1. However, often rare disease patients are ignored by doctors, researchers, and the general public. Referral triggers may also be different.

Branding 52

Branding Genome Genomics Genetics 52

XTalks

JULY 24, 2024

AI-driven models also help in identifying the most effective treatment regimens based on patient-specific factors, including genetic makeup and treatment history. Large datasets from clinical trials, patient records and genomic studies can be analyzed to identify patterns and correlations previously unattainable. Nanostics Inc.

Big Data 52

Big Data Clinical Trials Clinical Trials Life Science 52

Pharmaceutical Technology

NOVEMBER 4, 2022

And we're building this Data Commons, bringing in imaging data, genomic data, clinical health record data, which in Scotland is really well annotated already,” says McNeil. All data is anonymised to protect patient confidentiality. We're trying to understand why it’s increasing so much across the world, but Scotland in particular.

Medicine 130

Medicine Development Research Gene 130

pharmaphorum

FEBRUARY 26, 2021

Every time a patient with a rare condition walks into a hospital, doctors face the probable challenge of starting from scratch. Genetic testing has played a big role in enhancing the diagnosis process. For instance, the UK government’s 100K Genomes Project has achieved its goal of sequencing the genomes of 100,000 people in 2019.

Drugs 78

Drugs Genome Project Genome Genomics 78

Delveinsight

AUGUST 11, 2021

Many tech related tools are being developed to create applications or devices with higher accuracy using technology like genetics and pathology. Virtual and Augmented Reality Programs are aiding doctors by making patients see a complete technique of how a surgery is performed. Genome Sequencing. Drug Development.

Medicine 90

Medicine Drug Delivery Development Drug Delivery Systems 90

The Pharma Data

SEPTEMBER 1, 2021

Louis have genetically engineered cells that, when implanted in mice, will deliver a biologic drug in response to inflammation. The researchers used CRISPR-Cas9 genome editing technology to make cells that secrete a biologic drug in response to inflammation. million adults in the United States. 1 in the journal Science Advances.

Drugs 52

Drugs Engineer Drug Delivery Gene 52

XTalks

SEPTEMBER 16, 2024

This approach not only accelerates the clinical testing of new precision therapies but also facilitates the study of treatments for rarer genetic variations of lung cancer that would be challenging and costly to manage in traditional, individual trials. What role does technology play in supporting the trial’s infrastructure?

Clinical Trials 52

Clinical Trials Clinical Trials Trials Clinical Research 52

XTalks

OCTOBER 19, 2023

This specialization can often be achieved during graduate research, post-doctoral work or industry-specific training programs. Additionally, advances in technologies in fields like genomics, proteomics and cell biology necessitate specialized assays. Interning provides industry-relevant experience and can also help with networking.

Scientist 59

Scientist Development Research Compliance 59

Roots Analysis

SEPTEMBER 1, 2023

Blue Ocean Strategy Example: Foundation Medicine has developed a genomic profiling test that helps oncologists identify the best treatment options for their patients based on their genetic makeup. As the field continues to advance, it is expected to have a profound impact on the future of medicine.

Drug Delivery 52

Drug Delivery Marketing Drug Delivery Systems Drugs 52

pharmaphorum

JANUARY 29, 2021

Genome editing is an exciting but still nascent field, and companies in the area face as many obstacles as they do opportunities. ZFPs can be engineered to make zinc finger nucleases, or ZFNs, which are proteins that can be used to edit genomes by knocking select genes in or out to specifically modify DNA sequences.

Gene Editing 145

Gene Editing Gene Gene Therapy In-Vivo 145

pharmaphorum

SEPTEMBER 9, 2020

Geneticist Dr Charles Steward has spent his career studying the human genome – but his work became much more personal when his children were diagnosed with severe neurological diseases. Charlie told pharmaphorum how his search for a genetic cause has led him to straddle the divide between scientist and patient advocate.

Genome 103

Genome Genomics Genetics Genome Project 103

STAT News

MARCH 22, 2023

Stanford cardiologist Euan Ashley and his research team received a Guinness World Record last year for sequencing a full human genome in just over five hours. Ashley is at the forefront of a push by researchers to make more genetic information available to patients facing major health care decisions.

Genome 98

Genome Genomics Scientist Genetics 98

pharmaphorum

SEPTEMBER 9, 2020

Geneticist Dr Charles Steward has spent his career studying the human genome – but his work became much more personal when his children were diagnosed with severe neurological diseases. Charlie told pharmaphorum how his search for a genetic cause has led him to straddle the divide between scientist and patient advocate.

Genome 80

Genome Genomics Genetics Genome Project 80

pharmaphorum

SEPTEMBER 13, 2022

Thanks to the dedicated efforts of doctors, patients, carers, and healthcare professionals, people diagnosed with blood cancer are now living longer, with a steady stream of more effective treatments entering the market each year. 2012 – The 100,000 Genomics Project begins. This was an entirely new approach to DNA research.

Genome Project 98

Genome Project Genome Genomics DNA 98

The Pharma Data

AUGUST 16, 2021

The antiviral agent incorporates RNA-like building blocks into the RNA genome of the virus. If this genetic material is further replicated, defective RNA copies are produced and the pathogen can no longer spread. ” Mutations in the genome stop the virus. Molnupiravir is currently being tested in clinical trials. .”

RNA 52

RNA Drugs Genome Genomics 52

pharmaphorum

DECEMBER 7, 2021

They used computational techniques to sift through genetic and other biologic data as well as insurance claims information from a database of more than 7 million patients, and found that sildenafil had the greatest potential as an Alzheimer’s drug.

Drugs 52

Drugs Clinical Trials Clinical Trials Scientist 52

XTalks

FEBRUARY 11, 2021

The Human Genome Project recently marked 20 years since the publication of the first full sets of human genomic sequences, an endeavor that spanned well over a decade. Today, new next-generation sequencing technologies allow for the sequencing of complex genomes within just a day or two. Rosalind Franklin.

Genetics 119

Genetics DNA Genome Genomics 119

Pharma Marketing Network

JANUARY 20, 2021

In other areas of the industry (such as cell and genetic medicine development) progress continued at an impressively brisk pace despite the pandemic. Douglas Lee of Bayer Pharmaceuticals described this change as a major shift in how patients access healthcare and “a change in the mindset that you need to see the doctor for everything.”

Vaccine 52

Vaccine Vaccination In-Vivo Genetics 52

XTalks

OCTOBER 15, 2021

This included segregated wards at Johns Hopkins containing Black patients with cervical cancer whom white doctors would collect samples from without their knowledge or consent. The Lacks family is also concerned over the wide availability of Lacks’ genetic material, saying that “some of the most private information about Ms.

Vaccine 105

Vaccine Vaccination Gene Mapping Doctors 105

pharmaphorum

SEPTEMBER 1, 2020

Another military man in the drugs business was Edward Robinson Squibb, who as a naval doctor during the Mexican-American war of 1846–1848 threw the drugs he was supplied with overboard due to their low quality. This knowledge of genetics and the underlying cause of many diseases, including cancer, has resulted in powerful new drugs.

Medicine 145

Medicine Insulin Drugs Pharmacy 145

XTalks

FEBRUARY 26, 2021

Hollmann was a doctor at the Kalihi Hospital in Hawaii who wanted to find a way to extract the active ingredients of chaulmoogra oil so that it could be effectively administered to patients. He even became known as the “the plant doctor” among local farmers as he had the ability to improve the health of their fields, orchards and gardens.

Scientist 69

Scientist Research Genetics Cosmetics 69