pharmaphorum

AUGUST 23, 2022

To understand how quickly the industry responded, one need only look at the development history of Moderna’s COVID-19 vaccine: the company took all of two days to transition from receiving the genetic sequence of the virus to creating a vaccine candidate.

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Vaccine Vaccination Development Trials 134

pharmaphorum

NOVEMBER 24, 2020

The FDA has approved Alnylam’s gene silencing drug Oxlumo, the first treatment for primary hyperoxaluria type 1 (PH1), an ultra-rare and life-threatening genetic disorder. Oxlumo (lumasiran) was also approved in the European Union last week, making it the third from Alnylam’s pipeline of RNA interference therapeutics to make it to market.

FDA Approval 52

FDA Approval Gene Silencing Drugs RNA 52

STAT News

MARCH 6, 2023

Still, when doctors told her last year that the cancer was growing despite two operations, radiation therapy, and a fifth regimen of chemotherapy, the retired business-meeting facilitator decided to do something unorthodox: spend $83,000 out of pocket on an unproven experimental cancer vaccine.

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Vaccination Vaccine Drugs Clinical Trials 98

The Pharma Data

MAY 9, 2022

Currently, after surgery, doctors examine a specimen of a tumor under a microscope and grade it one, two or three in its aggressiveness. The paper was published today in Nature Genetics. “Eventually we hope to tailor medical therapy to the genetic changes within each individual person’s meningioma,” Magill said.

Drugs 52

Drugs Scientist DNA Genetics 52

The Pharma Data

NOVEMBER 18, 2020

Lab tests that look for the coronavirus’s genetic material using a technique called polymerase chain reaction (PCR) are still considered the gold standard for detecting the virus. Like PCR, the new test repeatedly copies genetic material until it reaches detectable levels. But the new at-home test relies on similar principles.

FDA Approval 52

FDA Approval Vaccination Vaccine Genetics 52

Bioengineer

JULY 23, 2021

. “By applying high-resolution imaging, advanced cell and molecular readouts and RNA sequencing methods leveraging the OTME-Chip, we discovered the actual genetic signaling pathways behind the blood cell triggered metastasis of ovarian cancer and a new drug strategy to stop this process.”

Engineer 52

Engineer Gene Editing Clinical Trials Clinical Trials 52

The Pharma Data

NOVEMBER 17, 2020

Both companies used a synthetic version of coronavirus genetic material called messenger RNA to program a person’s cells to churn out copies of a fragment of the virus, the Times said. Doctors say this reflects India’s younger and leaner population.

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Vaccination Vaccine RNA Allergies 52

The Pharma Data

NOVEMBER 10, 2020

The vaccine uses a technology never before used: Each injection contains lipid nanoparticles — fat bubbles — that surround a strip of genetic material called messenger RNA, the Post reported. The genetic material carries the blueprint for the distinctive spiky protein that protrudes from the virus’ surface.

Antibody 52

Antibody Vaccination Vaccine RNA 52

The Pharma Data

NOVEMBER 9, 2020

The vaccine uses a technology never before used: Each injection contains lipid nanoparticles — fat bubbles — that surround a strip of genetic material called messenger RNA, the Post reported. The genetic material carries the blueprint for the distinctive spiky protein that protrudes from the virus’ surface.

Vaccine 52

Vaccine Vaccination RNA Genetics 52

XTalks

SEPTEMBER 14, 2020

The company’s candidate vaccine, mRNA-1273, is a synthetic messenger RNA that encodes the stabilized SARS-CoV-2 spike protein. CanSino Biologics is developing a vaccine that involves snipping a bit of the virus’ genetic code off and coupling it with a harmless virus to provoke a SARS-CoV-2 immune response.

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Vaccine Vaccination Antibody Life Science 92