Doctors and Trials - Clinical Research Informer

July 23, 2024: Article From Ethics and Regulatory Core Highlights Key Challenges for Pragmatic Trials

Rethinking Clinical Trials

JULY 23, 2024

In an invited commentary published this month in Circulation: Cardiovascular Quality and Outcomes , authors from the NIH Pragmatic Trials Collaboratory’s Ethics and Regulatory Core describe the recurring and emerging ethical issues in pragmatic clinical trials. Learn more about the Ethics and Regulatory Core.

Trials

Trials Clinical Trials Clinical Trials Doctor

After surprise trial failure, ALS doctors brace for one less treatment option

Bio Pharma Dive

MARCH 12, 2024

Physicians are preparing for tough conversations with patients on Amylyx Pharmaceuticals’ drug, Relyvrio, while holding out hope it still may help some with the disease.

Doctor

Doctor Doctors Trials Drugs

Obesity drug from Zealand shows potential in early trial

Bio Pharma Dive

JUNE 20, 2024

Interim study data suggest the Danish drugmaker can remain in the race to develop new kinds of weight loss drugs as doctors seek alternatives to the now dominant GLP-1s.

Drugs

Drugs Doctor Doctors Trials

Doctors don’t have time for digital

World of DTC Marketing

APRIL 27, 2021

QUICK READ: Patients are returning to their doctor’s office, and it’s not uncommon for appointments, or routine visits, to be scheduled weeks or months in advance. When I sent an email to my doctor’s office, I was shocked when she said the earliest appointment she had for physicals was in September.

Doctor

Doctor Doctors Nurses Clinical Trials

What to make of Eisai and Biogen’s latest Alzheimer’s drug data

Bio Pharma Dive

NOVEMBER 29, 2022

At a medical conference, the companies detailed clinical trial results that could help support approval of their drug, lecanemab. However, some doctors aren’t yet convinced the medicine’s risks are worth its potential benefits.

Doctor

Teleconsultation positions itself as viable alternative to offset low doctor-to-population ratio & specialists shortage

AuroBlog - Aurous Healthcare Clinical Trials blog

MAY 23, 2023

Teleconsultation is seen as a viable alternative with low doctor-to-population ratio and shortage of specialists doctors. In fact, teleconsultation is seen to bridge this gap by allowing patients in remote areas to receive earlier diagnosis and treatment with low cost and faster follow-up check-ups.

Doctor

Doctor entrepreneurs seek healthcare management expertise to initiate best practices at clinics: Raj Sehgal

AuroBlog - Aurous Healthcare Clinical Trials blog

NOVEMBER 6, 2023

India’s smart doctor promoters are seeking help of professional healthcare management companies to introduce best healthcare management practices in their establishments, said Raj Sehgal associate director, TR Lifesciences. This is because these clinics encounter challenges even as there are growth prospects.

Doctor

Novo obesity drug protects heart health in large trial

Bio Pharma Dive

AUGUST 8, 2023

Treatment with Wegovy led to a 20% reduction in the relative risk of cardiovascular complications or death, a finding that could further shift how doctors treat obesity.

Doctor

Doctor Doctors Trials Drugs

Grand Rounds December 13, 2024: Home Blood Pressure Telemonitoring and Nurse Case Management in Black and Hispanic Patients With Stroke: A Randomized Clinical Trial (Gbenga Ogedegbe, MD, MPH, FACP)

Rethinking Clinical Trials

DECEMBER 18, 2024

This was a multisite, practice-based, comparative effectiveness randomized clinical trial conducted at six public hospitals and three academic medical centers in New York City. Sustainment can be an Achilles Heel for embedded trials, as programs that have been shown to be successful arent always covered by insurance.

Nurses

Nurses Clinical Trials Clinical Trials Trials

‘Useless’ Organ That Doctors Often Remove May Actually Fight Cancer

AuroBlog - Aurous Healthcare Clinical Trials blog

AUGUST 17, 2023

There’s a small fatty gland that sits behind your sternum and is often said to be ‘useless’ in adulthood.A

Doctor

Doctor Doctors Research Clinical Trials

UniQure offers a closer look at the leading hemophilia B gene therapy

Bio Pharma Dive

DECEMBER 8, 2020

Doctors on Tuesday got a more detailed idea of how the therapy works and who might be eligible to take it, as results from a late-stage trial were presented at ASH.

Gene Therapy

Gene Therapy Gene Doctor Doctors

Doctor Reveals What Happens When You Stop Taking Ozempic

AuroBlog - Aurous Healthcare Clinical Trials blog

APRIL 23, 2024

Drugs like Ozempic are very effective at helping most people who take them lose weight. Semaglutide (sold as Wegovy and Ozempic) and tirzepatide (sold as Zepbound and Mounjaro) are the most well known in the class of drugs that mimic hormones to reduce feelings of hunger. But does weight come back when you stop using […]

Doctor

Doctor Doctors Hormones Drugs

Expert Explains Why You Should Clean Your Tongue Twice a Day

AuroBlog - Aurous Healthcare Clinical Trials blog

SEPTEMBER 25, 2024

(Science Photo Library/Getty Images) Has your doctor asked you to stick out your tongue and say “aaah”? The doctor will look for any changes in the tongue’s surface or how it moves. While the GP assesses your throat, they’re also checking out your tongue, which can reveal a lot about your health.

Doctor

March 15, 2023: IMPACt-LBP Enrolls First Patient in Study of Collaborative Care for Low Back Pain

Rethinking Clinical Trials

MARCH 15, 2023

IMPACt-LBP, an NIH Pragmatic Trials Collaboratory Demonstration Project, enrolled its first study participant this week. Rishi Chakraborty Co-led by investigators at Duke University and Dartmouth University, IMPACt-LBP is a cluster randomized trial of a multidisciplinary collaborative team approach for low back pain versus usual care.

Clinical Trials

Doctors at Sahyadri Hospitals Pune warn of rising pulmonary embolism cases linked to international travel

AuroBlog - Aurous Healthcare Clinical Trials blog

JULY 23, 2024

Over the last two years, Sahyadri Hospitals in Pune has observed a troubling trend of increase in cases of pulmonary embolism (PE) associated with long-haul international travel.

Doctor

August 8, 2024: FDA Commissioner and NIH Director Share Thoughts on the Future of Pragmatic Clinical Trials

Rethinking Clinical Trials

AUGUST 8, 2024

Speaking at the NIH Pragmatic Trials Collaboratory’s 2024 Annual Steering Committee Meeting in May, Commissioner of Food and Drugs Robert Califf and NIH Director Monica Bertagnolli discussed the intersection of pragmatic research and national health priorities. It is imperative to get a learning health system in progress,” she said.

Clinical Trials

Using the Internet to reach doctors, numbers don’t matter. What you have to say and how you say are more important.

World of DTC Marketing

JUNE 10, 2021

On the other hand, we did make a thought elder, who worked on clinical trials of a cancer drug, to take questions from other physicians about those clinical trials. Finally, after the storm of the pandemic, many doctors re suddenly overwhelmed with patients. When using the Internet to reach doctors, numbers don’t matter.

Doctor

With little data to go on, experts question how useful Eisai, Biogen’s new Alzheimer’s drug will be

Bio Pharma Dive

SEPTEMBER 30, 2022

Positive results from a late-stage clinical trial of the drug, called lecanemab, were a surprising success for a field used to setbacks. But doctors and researchers point out that the reported benefit appears relatively modest.

Doctor

Florida Man’s Mystery Migraine Traced to Rare Case of Parasite in His Brain

AuroBlog - Aurous Healthcare Clinical Trials blog

APRIL 30, 2024

On closer inspection using a CT scan, the doctors discovered his severe headaches were the result of several cysts throughout his brain. A 52-year-old Florida man presented to hospital with complaints that his usual migraines had worsened over the past four months.

Doctor

Govt Siddha doctors in Kerala form new association to promote Siddha dispensaries in rural areas

AuroBlog - Aurous Healthcare Clinical Trials blog

OCTOBER 25, 2022

The Siddha medical practitioners working under the Kerala ISM department and assigned with various Central and state government projects have joined hands to form an organisation of government Siddha medical officers on the lines of the Kerala Government Ayurveda Medical Officers Association.

Doctor

Equal Parts Caregiver and Advocate: Clinical Trials from the Caregiver’s Point of View

Camargo

NOVEMBER 22, 2021

In this Q&A, Andrea discusses their experience, especially as it relates to the two clinical trials Tom participated in. We wanted to participate in a clinical trial. But our original doctor doesn’t work with clinical trials—it’s just not his thing. You aren’t thinking about treatments and trials.

Clinical Trials

Clinical Trials Clinical Trials Trials Research

Cranberry Juice Really Does Have Promising Benefits For UTIs

AuroBlog - Aurous Healthcare Clinical Trials blog

AUGUST 6, 2024

Today, unsweetened cranberry juice is often recommended by doctors as a treatment for urinary tract infections (UTIs), and yet given a lack of solid scientific evidence, some researchers have argued that “any continued promotion” of […]

Doctor

Doctor Doctors Research Clinical Trials

Running Through Life with Type 1 Diabetes

Worldwide Clinical Trials

NOVEMBER 13, 2024

In 2011, I participated in a Type 1 diabetes clinical trial and have continued exploring study opportunities ever since. I always kept up with my doctor’s appointments and insulin. Then in 2019, my doctor suggested a continuous glucose monitor (CGM) for better control. Still, I refused to let diabetes define me.

Insulin

Insulin Doctor Doctors Clinical Trials

Why We Still Use a 140-Year-Old Method to Diagnose UTIs

AuroBlog - Aurous Healthcare Clinical Trials blog

SEPTEMBER 7, 2022

Not just because of the physical pains it causes, but because it can also be such a pain to go to the doctor, provide a urine sample, and wait for your results. If you’ve ever had a urinary tract infection (UTI) before, you know what a pain it can be. Skip advert UTIs are extremely […].

Doctor

Do You Bruise Easily? It Could Be A Sign Of Something More Serious

AuroBlog - Aurous Healthcare Clinical Trials blog

OCTOBER 31, 2023

As hematologists (blood doctors), we are often asked for advice when people are worried they might bruise too easily. But what if we find ourselves bruising without any noticeable cause? What might be behind it? Should we worry? Around 18 percent of adults report easy bruising. Here […]

Doctor

Florida doctors' board tightens ban on gender-affirming care

Medical Xpress

FEBRUARY 10, 2023

A prohibition against puberty blocking hormones and gender-affirming surgeries for minors in Florida was tightened further after a board overseeing doctors eliminated an exception for clinical trials Friday at the request of Florida Gov. Ron DeSantis' administration.

Doctor

Doctor Doctors Hormones Clinical Trials

This Single Blood Test Can Detect Multiple Kinds of Cancer Early

AuroBlog - Aurous Healthcare Clinical Trials blog

NOVEMBER 6, 2022

This is why doctors recommend regular screening for several common cancer types, using a variety of methods. Detecting cancer early before it spreads throughout the body can be lifesaving. Colonoscopies, for example, screen for colon cancer, while mammograms screen for breast cancer.

Doctor

Traditional vs patient-centric clinical trial design

Deltaclinical

NOVEMBER 2, 2021

The sponsor of a study will assign one or multiple principle investigators (PI), usually a doctor. Along with a team of nurses and other stakeholders, the PI will conduct the trial at his/her study site. However, the sponsor will remain the monitor of the trial. Patient-centric clinical trial design.

Clinical Trials

Traditional vs patient-centric clinical trial design

Deltaclinical

NOVEMBER 2, 2021

The sponsor of a study will assign one or multiple principle investigators (PI), usually a doctor. Along with a team of nurses and other stakeholders, the PI will conduct the trial at his/her study site. However, the sponsor will remain the monitor of the trial.

Clinical Trials

Traditional vs patient-centric clinical trial design

Deltaclinical

NOVEMBER 2, 2021

The sponsor of a study will assign one or multiple principle investigators (PI), usually a doctor. Along with a team of nurses and other stakeholders, the PI will conduct the trial at his/her study site. However, the sponsor will remain the monitor of the trial. Patient-centric clinical trial design.

Clinical Trials

Traditional vs patient-centric clinical trial design

Deltaclinical

NOVEMBER 2, 2021

The sponsor of a study will assign one or multiple principle investigators (PI), usually a doctor. Along with a team of nurses and other stakeholders, the PI will conduct the trial at his/her study site. However, the sponsor will remain the monitor of the trial. Patient-centric clinical trial design.

Clinical Trials

Patient Perspective: Jamie Troil Goldfarb shares her clinical trial experience [video]

Antidote

JANUARY 29, 2024

For individuals living with a condition like melanoma, volunteering to participate in a clinical trial can be a rewarding experience. Individuals with Jamie’s specific diagnosis are given a 14% 5-year survival rate — but through participating in an immunotherapy clinical trial, Jamie is living without evidence of the disease.

Clinical Trials

Why we need the human element of remote clinical trials

pharmaphorum

FEBRUARY 5, 2021

Over the last year, we’ve noticed that “connectivity” doesn’t always equate to “connected” – and that’s just as true in the realm of clinical trials as it is in our personal lives. Amanda Barrell reports from a panel at the Patients as Partners Europe conference on remote clinical trials. They gave me a huge amount of support.”.

Clinical Trials

?“This [clinical] trial has given our family hope”: A story of cancer survivorship

Worldwide Clinical Trials

JUNE 7, 2022

By Cathy Purvis, MBA; Site Activation Manager, Oncology and Rare Disease, Worldwide Clinical Trials. I quickly became intrigued by the complex nature of the study/site processes and did whatever I could to meet and beat targets, despite the additional oversight that often accompanies oncology trials.

Clinical Trials

Digital clinical trials: Trends to watch in 2023

Pharmaceutical Technology

APRIL 13, 2023

Following the increased use of telemedicine during the Covid-19 pandemic, the potential of digital technologies in communication, data collection, and analysis has become increasingly realised by patients, healthcare systems, and clinical trial sponsors.

Clinical Trials

Clinical Trials Clinical Trials Trials Dermatology

Expiry date for prescription necessary to prevent AMR: AICDF

AuroBlog - Aurous Healthcare Clinical Trials blog

FEBRUARY 14, 2024

The Kolkata headquartered All India Chemists and Distributors Federation (AICDF), a breakaway group of the AIOCD and a body of pharmaceutical distributors and retailers across the country, has informed the government of West Bengal that a period of use or an expiry date, on the lines of the use of therapeutics, is necessary for doctors’ […]

Doctor