pharmaphorum

SEPTEMBER 23, 2020

Sixfold Bioscience in partnership with Medicines Discovery Catapult, has been given the green light, through the award of an Innovate UK Smart Grant to test a pioneering system designed to deliver drugs directly to cancerous cells, without impacting the healthy cells around it.

Drug Delivery Systems 141

Drug Delivery Systems Gene Silencing Drug Delivery Medicine 141

Roots Analysis

AUGUST 8, 2023

Pharmaceutical and Industrial Applications of Liposomes Liposomes are frequently used for the delivery of drugs, genes, vaccines, and diagnostic products. The figure highlights several parameters considered during liposome characterization.

Drug Delivery Systems 52

Drug Delivery Systems Drug Delivery Drugs In-Vivo 52

Roots Analysis

AUGUST 15, 2023

Below are the highlights that we feel would be helpful to understand about the intracellular drug delivery / intracellular non-viral drug delivery approach. WHAT IS INTRACELLULAR DRUG DELIVERY? The main issues with viral delivery approach are the immunogenicity and cytotoxicity.

Drug Delivery 52

Drug Delivery Drugs Drug Delivery Systems Gene 52

Roots Analysis

FEBRUARY 26, 2024

However, certain biological targets have long eluded drug development efforts. Scientific literature suggests that the RAS gene is mutated across about 30% of cancer types. One such target is Ras family, which has been identified to play a critical role in oncogenesis.

Drug Delivery Systems 52

Drug Delivery Systems Marketing Drug Delivery Development 52

Roots Analysis

MAY 21, 2024

Gene Therapies: LNPs have the ability to effectively deliver nucleic acids, including small interfering RNA (siRNA), messenger RNA (mRNA), and plasmid DNA to the target cells. In addition, these can be modified with ligands in order to improve the specificity and selectivity of the gene therapy and reduce off-target effects.

Drug Delivery 40

Drug Delivery Drugs Gene Therapy Bioavailability 40

The Pharma Data

SEPTEMBER 1, 2021

. “Doctors often treat patients who have rheumatoid arthritis with injections or infusions of anti-inflammatory biologic drugs, but those drugs can cause significant side effects when delivered long enough and at high enough doses to have beneficial effects,” said senior investigator Farshid Guilak, PhD, the Mildred B.

Drugs 52

Drugs Engineer Drug Delivery Gene 52

Roots Analysis

OCTOBER 5, 2023

Driven by the increasing need for safe and efficient medical devices and drug delivery systems, the pharmaceutical polymers / medical grade polymers domain is advancing significantly. There has been a rise in the development of polymers for biopharma with improved biocompatibility, biodegradability and functionality.

Manufacturing 40

Manufacturing Drug Delivery Systems Drug Delivery Packaging 40