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The complement-targeted therapeutics inhibit complement activation, thereby reducing tissue inflammation and dampening the adaptive immuneresponse to foreign and tissue antigens. Next Generation Complement Therapeutics – Current Market Landscape. Next Generation Complement Therapeutics. Broad Clinical Trial Landscape. Web: [link].
LNPs comprise of a lipid bilayer that surrounds a hydrophobic core, which can be loaded with therapeutic agents ( such as drugs, genetic material and proteins ). The average size of LNPs typically ranges from 40 to 1,000 nanometers, which allows efficient cellular uptake and intracellular delivery.
In an email to this news service, João Conde, PhD, professor at NOVA Medical School, Universidade NOVA de Lisboa, said advances like the mRNA vaccines serve as a testament to the breakthroughs made by science over decades of research at the junction of genetics and nanomedicine. These could feature in the next four to five years.
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