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In 1974, Dr. Robert Langer was part of the first cohort of researchers to begin nanoparticle research , as his lab at Cornell University developed tiny particles to deliver large molecules for angiogenesis. The next wave came from early research into liposomes and lipid nanoparticles, both of which are used for drugdelivery.
The production of commercial dose non-sterile products such as tablets, capsules, ointments, creams, and powders is rising due to their growing global demand, attributed to increasing demand for anti-ageing products, hereditary factors, genetic mutations, exposure to harmful radiation, and rising geriatric population.
Genomics is the study of genetic material within a cell, and transcriptomics is the study of gene activity in different cells. This approach is often employed to determine the effect of genetic modifications or therapeutics in pharmacokinetic studies of drug metabolism. Untargeted Metabolomics. Our Social Media Platform.
In recent years, liposomes have garnered significant interest of researchers, as well as industry players, owing to their potential in diagnosis and treatment of various diseases, with a focus on delivering drugs and genetic material. Majority of the articles (51%) are focused on evaluating liposomes for use in cancer therapy.
In the 20 th century, major research went into discovery of a therapeutic class with the primary purpose of interfering with the RNA expression linked to disease causing proteins, nowadays classified as oligonucleotides. Till date, 14 oligonucleotide-based therapies have been approved. Our Social Media Platform. Web: [link]. LinkedIn: [link].
Majority of these are biologics and are being developed for the treatment of different disease conditions, including dermatological, genetic, hematological and vascular, immunological and inflammatory, infectious, neurological, ophthalmic, renal disorders. High Number of Patents are Suggestive of the Widespread Research in this Domain.
Certain areas where this technology is working hand-in-hand with healthcare are: Unsustainable healthcare systems into sustainable ones Equalizing the relationship between medical professionals and patient Provide cheaper, faster and more effective solutions for diseases. Drug Development. Management & Administration.
With a goal of developing rheumatoid arthritis therapies with minimal side effects, researchers at Washington University School of Medicine in St. Louis have genetically engineered cells that, when implanted in mice, will deliver a biologic drug in response to inflammation. million adults in the United States.
Real World Data and Blue Ocean Strategy Real-world data is particularly useful for researchers, as it provides valuable insights from patient data and knowledge that can impact many decision-making processes. Ronit holds a B.
Clinical research experts from the CRO Medpace shared insights about the operational and regulatory considerations for neuroscience trials with direct CNS administration. In a recent webinar, Dr. Vornov described the history and current progress in targeted CNS therapeutic delivery. Viral Vectors for Gene Delivery to the CNS.
The question arises here is, does the intracellular drugdelivery only applicable for cancer or any other diseases as well? It can be used to treat a variety of disorders including cardiovascular disorders, hepatic disorders, genetic disorders and many more. The answer is yes. million lives each year. million lives each year.
It transfers genetic information form to DNA to ribosomes, a specialized structure, or organelle, which decodes genetic information into a protein. With the help of genetic engineering, synthetic mRNAs can express proteins, as they structurally resemble a natural mRNA.
Amidst the ongoing initiatives to develop therapeutic interventions with improved bioavailability, lipid nanoparticle (LNPs) have specifically attracted the attention of researchers and drug developers. This approach can enable synergistic effects, improved therapeutic outcomes, and reduced drug resistance.
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