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Innovate UK funding for new precision cancer treatment technology

pharmaphorum

Sixfold Bioscience in partnership with Medicines Discovery Catapult, has been given the green light, through the award of an Innovate UK Smart Grant to test a pioneering system designed to deliver drugs directly to cancerous cells, without impacting the healthy cells around it.

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Liposome: A Novel Drug Delivery System

Roots Analysis

Furthermore, a wide variety of drugs and macromolecules, including DNA , proteins, and imaging agents, can be encapsulated in liposomal vesicles due to their unique ability to entrap both lipophilic and hydrophilic substances. The various therapeutic applications of liposomes in drug delivery have been highlighted in the figure.

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Intracellular Drug Delivery – A Potential Treatment for Lethal Orphan Diseases

Roots Analysis

We have put in our best effort to make it easily graspable what are the intracellular drug delivery technologies and how it can ensure effective treatment for fatal disease. Below are the highlights that we feel would be helpful to understand about the intracellular drug delivery / intracellular non-viral drug delivery approach.

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The Power of Lipids: Enhancing Drug Delivery with Nanoparticles

Roots Analysis

In addition, NLCs offer benefits such as high drug loading capacity, improved drug retention and avoidance of drug expulsion. Advantages of Lipid Nanoparticle LNPs are gaining significant attention of formulation scientists in drug delivery due to the various advantages offered by them.

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Considerations for Neuroscience Trials with Intrathecal Delivery and Other Methods of Direct CNS Administration

XTalks

One of the biggest challenges with developing therapies to treat CNS disorders is the delivery of systemically administered investigational products (IPs) to the brain, which is limited by the blood-brain barrier. Some methods of direct CNS administration include intrathecal, intraparenchymal and intracerebroventricular (ICV) delivery.

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New Frontiers in Cancer Therapies: Focus on Transcription Factors, GTPases, Phosphatases and GPCRs, 2018-2030

Roots Analysis

However, certain biological targets have long eluded drug development efforts. Scientific literature suggests that the RAS gene is mutated across about 30% of cancer types. One such target is Ras family, which has been identified to play a critical role in oncogenesis.

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Rheumatoid arthritis treated with implanted cells that release drug

The Pharma Data

. “Doctors often treat patients who have rheumatoid arthritis with injections or infusions of anti-inflammatory biologic drugs, but those drugs can cause significant side effects when delivered long enough and at high enough doses to have beneficial effects,” said senior investigator Farshid Guilak, PhD, the Mildred B.

Drugs 52