Outsourcing Pharma

AUGUST 23, 2024

Janssen-Cilag International NV, a Johnson & Johnson company, announced that the European Commission (EC) has approved Balversa (erdafitinib) as a once-daily oral monotherapy for adult patients with unresectable or metastatic urothelial carcinoma (mUC) harboring susceptible FGFR3 genetic alterations.

Genetics 80

Genetics Drug Delivery Drugs 80

Scienmag

JANUARY 8, 2021

The research answers a long-standing biological question and could have implications for the timing of drug delivery, biotechnology, and […]. Now research reveals that bacteria too have internal clocks that align with the 24-hour cycle of life on Earth.

Bacteria 66

Bacteria Drug Delivery Research Drugs 66

XTalks

AUGUST 30, 2022

One of the biggest challenges with developing therapies to treat CNS disorders is the delivery of systemically administered investigational products (IPs) to the brain, which is limited by the blood-brain barrier. Some methods of direct CNS administration include intrathecal, intraparenchymal and intracerebroventricular (ICV) delivery.

Trials 83

Trials Drug Delivery Drugs Gene 83

pharmaphorum

AUGUST 10, 2020

This research also shows the complex system that drives our health outcomes, including the environment, our genetics and our social circumstances. Personalisation : creating interventions based on individuals knowing their genetics, biology and psychology as well as their social and geographical environment.

Genetics 124

Genetics Drug Delivery Research Pharma Companies 124

Roots Analysis

MARCH 16, 2023

It is important in the process of protein synthesis because mRNA is responsible for transferring genetic information from DNA to ribosomes, which then decodes the genetic information into a protein. In the last few years, researchers have become interested in using in vitro transcribed (IVT) mRNA as a drug delivery agent.

Vaccine 52

Vaccine Vaccination DNA Protein 52

pharmaphorum

NOVEMBER 1, 2022

The new master agreement, covering another five years, will foster research on genetic medicines, intrathecal delivery of therapeutics into the spinal canal or subarachnoid space of the brain, and the use of nanoparticles to improve drug delivery. million provided in 2017 for a five-year programme.

Manufacturing 52

Manufacturing Life Science Drug Delivery Medicine 52

Delveinsight

AUGUST 11, 2021

Many tech related tools are being developed to create applications or devices with higher accuracy using technology like genetics and pathology. Drug Development. Certain procedures like targeting a chemical combination that might be optimum to create a drug, reducing human time is crucial aid to drug discovery.

Medicine 90

Medicine Drug Delivery Development Drug Delivery Systems 90

Roots Analysis

SEPTEMBER 1, 2023

Blue Ocean Strategy Example: Foundation Medicine has developed a genomic profiling test that helps oncologists identify the best treatment options for their patients based on their genetic makeup. Furthermore, new drug delivery methods can also help reduce healthcare costs by reducing the need for frequent doctor visits and hospitalizations.

Drug Delivery 52

Drug Delivery Marketing Drug Delivery Systems Drugs 52

Roots Analysis

FEBRUARY 14, 2023

In recent years, liposomes have garnered significant interest of researchers, as well as industry players, owing to their potential in diagnosis and treatment of various diseases, with a focus on delivering drugs and genetic material.

Development 52

Development Manufacturing Drug Delivery Systems Contract Manufacturing 52

Roots Analysis

FEBRUARY 18, 2022

These short, single-stranded DNA or RNA molecules have various applications in biopharmaceutical and biotechnology industries including, genetic testing, basic research, forensic analysis and other analytical procedures. Till date, 14 oligonucleotide-based therapies have been approved. Our Social Media Platform. Web: [link]. LinkedIn: [link].

Contract Manufacturing 52

Contract Manufacturing Manufacturing Drug Delivery Systems RNA 52

The Pharma Data

SEPTEMBER 1, 2021

Louis have genetically engineered cells that, when implanted in mice, will deliver a biologic drug in response to inflammation. “These cells can sense problems and respond by producing a drug. A genome-engineered bioartificial implant for autoregulated anticytokine drug delivery. Science Advances, Sept.

Drugs 52

Drugs Engineer Drug Delivery Gene 52

Roots Analysis

OCTOBER 13, 2023

Over the last two decades the pharmaceutical industry has observed a paradigm shift from conventional drug delivery strategies to more enhanced, potent, and targeted therapeutics. This led the researchers to find alternative pathways and drug delivery strategies to enhance the potent delivery of the drug to the site of action.

Drugs 40

Drugs Antibody RNA Genetics 40

Roots Analysis

MARCH 3, 2022

Majority of these are biologics and are being developed for the treatment of different disease conditions, including dermatological, genetic, hematological and vascular, immunological and inflammatory, infectious, neurological, ophthalmic, renal disorders. Next Generation Complement Therapeutics. Broad Clinical Trial Landscape. Web: [link].

Drug Delivery Systems 52

Drug Delivery Systems Marketing Immune Response Dermatology 52

Roots Analysis

MARCH 24, 2022

Genomics is the study of genetic material within a cell, and transcriptomics is the study of gene activity in different cells. This approach is often employed to determine the effect of genetic modifications or therapeutics in pharmacokinetic studies of drug metabolism. Untargeted Metabolomics. Our Social Media Platform.

Clinical Research 52

Clinical Research Development Research Drug Delivery Systems 52

FDA Law Blog

JANUARY 5, 2023

The current Team Lead for Injection Devices in CDRH’s Division of Drug Delivery and General Hospital Devices and Human Factors noted that depending on the product, the pre-market path for a connected combination product might require an IND, IDE, or a determination that it is a medical device data system , which are not regulated as devices.

Regulation 59

Regulation Production Drug Delivery Marketing 59

BioSpace

NOVEMBER 17, 2022

Editas Medicine is pausing its ocular gene therapy program after demonstrating a favorable safety profile and seeking a potential partner to develop EDIT-101, the company announced Thursday.

Gene Therapy 42

Gene Therapy Gene Gene Editing Medicine 42

XTalks

MAY 30, 2024

The exact cause of this immune response is unknown, and there appears to be no identifiable genetic predisposition to CIDP. This innovative formulation uses Halozyme’s Enhanze drug delivery technology, facilitating the subcutaneous administration of biologics. new cases per 100,000 people annually.

FDA Approval 40

FDA Approval Immune Response Trials Drug Delivery 40

The Pharma Data

NOVEMBER 4, 2020

. Relying on independent research and development, the Company has formed gene recombination and fermentation engineering technology, and developed a number of core technologies, such as recombinant collagen, enzymatic and genetic engineering synthesis of bioactive peptides.

Licensing 40

Licensing Licensing Dermatology Production 40

Roots Analysis

JANUARY 30, 2023

Hence, a precision therapy or we can say a target therapy (involving intracellular drug delivery) is much needed to all the patients suffering from cancer. Here is how the intracellular drug delivery comes into action for majority of the fatal diseases that requires target therapy. The answer is yes.

Drug Delivery 52

Drug Delivery Drug Delivery Systems Drugs Marketing 52

XTalks

OCTOBER 1, 2020

Xtalks spoke with WeiQi Lin, MD, PhD, executive vice president, research & development, and principal scientist at DURECT Corporation — a company focused on developing drugs and drug delivery methods in therapeutic areas with significant unmet need — about her transition from academia to industry.

Scientist 52

Scientist In-Vitro Research Life Science 52

Roots Analysis

OCTOBER 22, 2023

RNA therapeutics are a novel class of biopharmaceuticals that harness the power of RNA molecules for the treatment and prevention of a wide range of disorders, including oncological, and genetic disorders as well as infectious diseases. These therapeutics are broadly classified into two categories, namely coding RNAs and non-coding RNAs.

RNA 40

RNA Protein Genetics Gene Expression 40

XTalks

OCTOBER 1, 2024

Overcoming the Challenges of mRNA Drug Development Developing mRNA therapeutics for respiratory conditions presents unique challenges, particularly in terms of drug delivery and stability. I believe that mRNA-based therapeutics have a bright future in respiratory medicine,” Dr. Langenickel reflects.

Development 52

Development Drugs Immune Response Protein 52

Delveinsight

FEBRUARY 25, 2021

Beam adds to drug delivery stable with USD 120 Million GuideTx buy. Beam Therapeutics has taken over a startup whose technology could proffer the biotech’s genetic medicines to more tissues in the body, widening the potential to approach more diseases. Beam employs three approaches to deliver its genetic medicines to cells.

DNA 52

DNA In-Vivo Genetics Medicine 52

pharmaphorum

DECEMBER 15, 2022

Oxsonics Therapeutics, which offers an ultrasound-based drug delivery platform, appointed Jérôme Marzinski, a board member at Cimon Medical and former CEO of ophthalmic diagnostic company Visiometrics into its top job. More CEO shakeups.

Sales 52

Sales In-Vitro Antibody Drug Delivery 52

Roots Analysis

FEBRUARY 13, 2023

It transfers genetic information form to DNA to ribosomes, a specialized structure, or organelle, which decodes genetic information into a protein. With the help of genetic engineering, synthetic mRNAs can express proteins, as they structurally resemble a natural mRNA.

Manufacturing 52

Manufacturing Drug Delivery Systems Genetic Engineering RNA 52

Roots Analysis

MAY 21, 2024

LNPs comprise of a lipid bilayer that surrounds a hydrophobic core, which can be loaded with therapeutic agents ( such as drugs, genetic material and proteins ). The average size of LNPs typically ranges from 40 to 1,000 nanometers, which allows efficient cellular uptake and intracellular delivery.

Drug Delivery 40

Drug Delivery Drugs Gene Therapy Bioavailability 40