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The study included 754 adolescents, comparing immuneresponses and safety profiles between vaccine and placebo groups. Chikungunya, a mosquito-borne viral disease, causes severe joint pain, fever and rash, with symptoms that can linger for months or even years.
The authorization was based on trial data that showed the vaccine was safe, well-tolerated and induced robust immuneresponses among children in this age group; side effects were generally mild to moderate. Genentech’s New Ocular Implant DrugDelivery System for Macular Degeneration Could Be a Game Changer.
Dr. Bryan began his career at Schering-Plough, engaging in formulation and drugdelivery. Unlike traditional therapies that act on the immune cascade after it has been initiated, Revolo’s treatments act at the very beginning of the immuneresponse.
CIDP is a rare autoimmune disorder where the body’s immune system mistakenly attacks its own tissues. The exact cause of this immuneresponse is unknown, and there appears to be no identifiable genetic predisposition to CIDP. Researchers estimate that the incidence of CIDP in the US ranges from 0.8
Additionally, a collaboration with NurExone is creating an intranasal delivery system for exosome-based therapies targeting spinal cord injuries, with potential expansion into other neurological uses. Polyrizon’s focus on intranasal protection aligns with a rapidly expanding market in drugdelivery innovation.
In the context of asthma, this means potentially restoring the immuneresponse in the respiratory tract to better protect against viral infections that often trigger severe asthma symptoms. These aggregates can trigger unwanted immuneresponses and reduce transfection efficiency.
Approved by the US Food and Drug Administration (FDA) in May 2023, Arexvy is designed to prevent lower respiratory tract disease (LRTD) caused by RSV in older adults. The trial assessed vaccine efficacy using RSV-LRTD cases, which refer to lower respiratory tract infections caused by RSV, leading to complications like pneumonia.
In order to help circumvent these disadvantages, several drugdelivery devices, which enable patients to self-administer drugs through subcutaneous route are now being developed. Moreover, protein-based drugs are also well tolerated inside the body, thereby reducing the chances of causing any immuneresponse in the body.
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