article thumbnail

Considerations for Neuroscience Trials with Intrathecal Delivery and Other Methods of Direct CNS Administration

XTalks

One of the biggest challenges with developing therapies to treat CNS disorders is the delivery of systemically administered investigational products (IPs) to the brain, which is limited by the blood-brain barrier. Some methods of direct CNS administration include intrathecal, intraparenchymal and intracerebroventricular (ICV) delivery.

Trials 83
article thumbnail

Best Toenail Fungus Treatment Products

Druggist

It is recommended that a particular group of people; for example, diabetic patients seek advice from a podiatrist or diabetic nurse as any infections in diabetes may lead to complications. Novel Drug Delivery Strategies for the Treatment of Onychomycosis. J Am Board Fam Med. 2011 Jan-Feb;24(1):69-74. doi: 10.3122/jabfm.2011.01.100124.

Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

article thumbnail

Unlocking the potential of direct-to-patient as decentralised trials continue to grow

Pharmaceutical Technology

This challenging environment, in addition to the measures taken to restrict people’s movement in order to reduce the viruses spread, led to many of the vital clinical trials being carried out to shift towards decentralised trial procedures that utilised virtual medicine and direct-to-patient (DtP) drug delivery.

Trials 130
article thumbnail

DEA’s Expected Guidance: It Should Reduce Current “Pain” at the (Intrathecal Pain) Pump Dispensing Process and Improve Therapeutic Outcomes

FDA Law Blog

For example, intrathecal infusion therapy, via an implanted infusion pump, or Targeted Drug Delivery (TDD”), is a last-line therapy for patients who have failed all other conventional pain therapies. In either event, the 2016 DEA guidance letter is not currently published or otherwise available on DEA’s guidance portal. [4]