McMaster drug trial receives more than $6m to test smallpox vaccine against mpox
Pharma Times
AUGUST 15, 2024
Children accounted for the majority of mpox cases and deaths in the DRC since June 2023
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STAT+: Pfizer scraps half of participants in Lyme disease drug trial due to quality issues
STAT News
FEBRUARY 17, 2023
Pfizer and partner Valneva are scrapping data from roughly half of the participants in a Phase 3 trial of a Lyme disease vaccine candidate after uncovering quality issues with a third-party clinical trial operator.
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Malaria Vaccine a Breakthrough Success with 77 Percent Efficacy
XTalks
APRIL 26, 2021
After years of disappointing malaria vaccine trials, a malaria shot developed by researchers at the Jenner Institute at the University of Oxford has demonstrated an unprecedentedly high efficacy of 77 percent, and may be the magic bullet the world has been waiting for against the deadly disease.
Mathematical models and computer simulations are the new frontiers in COVID-19 drug trials
Scienmag
JULY 18, 2021
Researchers are using computer models to simulate COVID-19 infections on a cellular level – the basic structural level of the human body. The models allow for virtual trials of drugs and vaccines, opening the possibility of pre-assessment for drug and vaccine efficacy against the virus.
Scepticism in press over Kintor’s COVID-19 US drug trial
pharmaphorum
MAY 14, 2021
China’s Kintor Pharmaceutical has begun late-stage US clinical development of its potential COVID drug proxalutamide – but there is scepticism over the company’s claims about its research. Reuters also pointed to other links with one of the study authors and Brazil’s vaccine sceptic president, Jair Bolsonaro.
Phases of Clinical Research: A Detailed Overview
Advarra
JUNE 27, 2023
Clinical trials are studies involving human volunteers to research ways to prevent, detect, and treat various medical conditions. The goal is to identify safer, more effective methods of treating illnesses using new drugs or new combinations of existing drugs.
Grand Rounds July 29, 2022: Effect of Early Treatment With Single-Dose Pegylated Interferon Lambda Among Patients With COVID-19: Results From The TOGETHER Trial (Edward Mills, PhD, FRCP; Jeffrey S. Glenn, MD, PhD)
Rethinking Clinical Trials
AUGUST 4, 2022
Department of Health Research Methods, Evidence & Impact. The trial has enrolled 1,900 high-risk non-hospitalized and 84% of patients were vaccinated to some extent, from July 2021-Feb 2022. It was a big treatment effect observed in a predominantly vaccinated population. Edward Mills, PhD, FRCP. Glenn, MD, PhD.
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