article thumbnail

Open Source “Wikipedia” for Drug Discovery

Pharma Mirror

Open source drug discovery was proposed in the past in connection with third-world diseases like tuberculosis and malaria, but it is in the context of first-world indications where it is needed most. In 2003 the Human Genome Project provided the first atlas. By Kambiz Shekdar, Ph.D.

article thumbnail

Magazine: Genomic projects exploit scale as clinical applications play catch-up

Pharmaceutical Technology

This month, we take a look at emerging research in this area , including that from the United Kingdom’s 100,000 Genomes Project, and understand how clinical applications could follow in the near future. You can also subscribe here to receive email notifications when a new issue is available.

Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

article thumbnail

Genomic projects exploit scale as clinical applications play catch-up

Pharmaceutical Technology

In a Nature publication , Florian Markowetz, PhD, and his fellow researchers analyzed copy number signatures across a number of cancers, and found 17 types of chromosomal instability while identifying 49 new drug targets. Space for discovery, development, and repurposing of drugs. Applicability caveats for genomic data remain.

article thumbnail

UK agency pilots biobank to study links between genetics and drug side effects

Pharmaceutical Technology

The Medicines and Healthcare products Regulatory Agency (MHRA) aims to launch a pilot genetic biobank that will gather patient data to associate drug-related adverse events to their genetic makeup. The Yellow Card biobank will launch as a joint venture with the UK-government funded entity Genomics England on June 1.

article thumbnail

A new dawn of the genomic age: five areas set to be transformed in 2023

pharmaphorum

For example, pilot data from the MHC Diversity in Africa Project has already highlighted the breadth of genetic diversity in Africa – with individual villages having greater genetic diversity than that seen in all of Europe. Understanding individual drug reactions and metabolism Pharmacogenomics is emerging as an important area.

Genome 129
article thumbnail

Can genetic data be a magic bullet for drug R&D?

pharmaphorum

Drug development has long been an issue for the pharma industry, due to the expense and the high failure rate of potential treatments. Ben Hargreaves finds that the vast amount of genetic data that exists today could help provide a faster, more targeted way of developing new drug candidates.

article thumbnail

COSMIC database matches drugs to cancer mutations

pharmaphorum

The world’s largest database of cancer mutations can now be used to link mutations with drug treatments in what promises to be a step forward in precision oncology. . The post COSMIC database matches drugs to cancer mutations appeared first on.

Drugs 59