Worldwide Clinical Trials

DECEMBER 19, 2024

At the recent World Orphan Drug Congresses (WODC) in Europe and the United States, Worldwide Clinical Trials Derek Ansel , Vice President, Therapeutic Strategy Lead, Rare Disease, facilitated roundtable discussions to explore the operational challenges and ethical barriers surrounding genetic testing.

Genetics 130

Genetics In-Vitro Drugs Clinical Trials 130

Bio Pharma Dive

FEBRUARY 8, 2022

Sandrock's appointment to Verge Genomics' board of directors follows about a week after the executive took up a similar post with Voyager Therapeutics.

Scientist 246

Scientist Genome Genomics Drugs 246

pharmaphorum

JANUARY 26, 2023

2022 was a banner year for genomics. In March, the collaborative T2T consortium published the first complete telomere-to-telomere sequence of the human genome, filling in the last 8% of the 3 billion base pairs that make up our DNA.

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Genomics Genome Genome Project Genetics 129

pharmaphorum

SEPTEMBER 14, 2020

Here he gives us a deeper look at how genomic medicine is evolving and the barriers that are preventing it from reaching its full potential. I saw this, in particular, with the finishing of the human genome,” says Charlie. “At In reality, finishing the human genome was the first step of what is a long journey.”.

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Genomics Genome Medicine Gene 119

Pharmaceutical Technology

JUNE 30, 2022

Analysing almost eight thousand tumours across 33 different cancers, researchers say this marks the first time that a framework was created to understand the role of internal factors in driving such genomic alterations. Genomic research have greatly expanded our understanding of disease pathophysiology over the years.

Genome Project 130

Genome Project Genomics Genome DNA 130

pharmaphorum

OCTOBER 16, 2024

The pandemic served as a catalyst for a revolution in genomic surveillance for tracking pathogens. The technology proved vital in aiding understanding of the evolution of and spread of virus in real time to inform public health measures, ultimately accelerating drug and vaccine development.

Genome 115

Genome Genomics Vaccine Vaccination 115

XTalks

APRIL 21, 2023

The application of whole genome sequencing (WGS) to derive a more complete understanding of cancer has been a central goal of cancer researchers even before the first human genome was decoded in 2003. Ultima Genomics has already partnered with other leading biotech startups.

Genomics 97

Genomics Genome Bioinformatics Genetics 97

BioSpace

AUGUST 30, 2020

When Bionano Genomics acquired Lineagen, Inc. in August, the genomic analysis company gained the final piece it needed to provide comprehensive structural variation detection for researchers and drug developers and a reimbursement pathway for clinicians who want to use its technology to replace c.

Genomics 120

Genomics Genome Development Drugs 120

Bio Pharma Dive

SEPTEMBER 12, 2023

Johnson & Johnson and Bristol Myers Squibb have joined a group of new investors backing Rosana Kapeller’s startup, which launched in 2020 after incubating with GV.

Genome 180

Genome Genomics Drugs 180

Pharmaceutical Technology

JULY 26, 2022

The last few months have marked the publication of research emerging from projects designed to collect and analyse genomic data on a wider scale than was previously thought possible. The post Magazine: Genomic projects exploit scale as clinical applications play catch-up appeared first on Pharmaceutical Technology.

Genome Project 130

Genome Project Genomics Genome Clinical Trials 130

pharmaphorum

OCTOBER 12, 2022

David Del Bourgo (CEO and co-founder, Whitelab Genomics) has always been passionate about introducing disruptive, innovative technologies to markets. We founded Whitelab Genomics after realising the potential to use data, data science, and AI in a more systematic way to develop genomic therapies,” Del Bourgo says.

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Genomics Genome Medicine Development 105

pharmaphorum

JUNE 13, 2022

Canary Wharf’s bid to become a new hub for the life sciences sector in the UK has been given a boost following the decision by Genomics England to relocate to the development. Genomics England will move into space at the iconic One Canada Square skyscraper (pictured) that was the EMA’s home before the move to the Netherlands.

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Genome Genomics Life Science Genome Project 111

Pharma Times

NOVEMBER 29, 2023

The new state-of-the-art facility is set to be operational in early 2024 - News - PharmaTimes

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Genome Genomics Drugs 164

Pharmaceutical Technology

SEPTEMBER 11, 2023

Alexion has entered into a partnership with Verge Genomics to detect new drug targets for rare neurodegenerative and neuromuscular ailments.

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Genomics Genome Drugs 147

pharmaphorum

MARCH 12, 2021

The UK regulator has authorised Eli Lilly’s targeted cancer drug Retsevmo for tumours with RET fusion positive lung cancers and thyroid cancers, which the company said could herald a new era of genomic medicine for the NHS. The post New era of genomic medicine begins as UK approves Lilly’s Retsevmo appeared first on.

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Genomics Genome Medicine Regulation 111

pharmaphorum

NOVEMBER 27, 2022

A group representing pharma companies selling precision therapies for cancer has called for a change to the way genomic testing is done in Scotland, to make sure patients get access to targeted drugs. The post Genomic testing ‘should be offered to all cancer patients in Scotland’ appeared first on. Why not lead?”

Genomics 104

Genomics Genome Genetics Medicine 104

Pharmaceutical Technology

JUNE 29, 2022

The US Food and Drug Administration (FDA) put a high-profile bluebird bio trial for sickle cell disease on partial clinical hold, and advisory panels deliberated over decisions involving gene therapies for amyotrophic lateral sclerosis (ALS), cerebral adrenoleukodystrophy (CALD), and beta-thalassemia.

Drugs 246

Drugs FDA Approval Development Marketing 246

Scienmag

JULY 11, 2022

SAN DIEGO, Calif.

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Genome Genomics Medicine Drugs 83

Drug Discovery World podcast

MARCH 26, 2025

This is the latest episode of the free DDW narrated podcast, titled Innovation enabled by new drug discovery technologies, which covers two articles written for DDW Volume 24 Issue 3, Summer 2023. The post Innovation enabled by new drug discovery technologies appeared first on Drug Discovery World (DDW).

Drugs 52

Drugs DNA Genome Genomics 52

pharmaphorum

SEPTEMBER 12, 2022

This reach allows us to support 82% of the novel drugs and therapeutic products approved by the US FDA, including 63% of those specific to oncology,” Reddy states. Everyone’s genetic makeup differs, and each person’s cancer experience is unique to them – how cancer develops, how fast it spreads, which drugs it responds to, and more.

Genomics 105

Genomics Genome Clinical Trials Clinical Trials 105

Pharmaceutical Technology

SEPTEMBER 29, 2023

HitGen and the Structural Genomics Consortium entered a collaboration to discover drugs based on a DNA-encoded library (DEL).

DNA 130

DNA Genomics Genome Drugs 130

Pharmaceutical Technology

MAY 25, 2023

The Medicines and Healthcare products Regulatory Agency (MHRA) aims to launch a pilot genetic biobank that will gather patient data to associate drug-related adverse events to their genetic makeup. The Yellow Card biobank will launch as a joint venture with the UK-government funded entity Genomics England on June 1.

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Biobanking Genetics Genome Project Genome 130

AuroBlog - Aurous Healthcare Clinical Trials blog

JUNE 11, 2023

The Central Drugs Standard Control Organisation (CDSCO) has declared a batch of Typbar, the typhoid polysaccharide vaccine from Bharat Biotech International Ltd as not of standard quality (NSQ).

Vaccine 180

Vaccine Vaccination Genome Genomics 180

Scienmag

FEBRUARY 12, 2021

Research offers new lead for cancer drug discovery Credit: Rensselaer Polytechnic Institute TROY, N.Y. — An antioxidant found in green tea may increase levels of p53, a natural anti-cancer protein, known as the “guardian of the genome” for its ability to repair DNA damage or destroy cancerous cells.

Genome 98

Genome Genomics DNA Protein 98

XTalks

MARCH 1, 2024

In a pivotal move for the food industry, the US Food and Drug Administration (FDA) has unveiled industry guidance for genome edited foods derived from plants. This landmark guidance aims to demystify the FDA’s risk-based approach towards both genome edited foods and all new plant varieties. What is Genome Editing?

Genomics 86

Genomics Genome Production Marketing 86

AuroBlog - Aurous Healthcare Clinical Trials blog

NOVEMBER 1, 2022

As drug companies have embarked on an initiative to launch affordable medicines for rare diseases in India, experts have called for using pharmacogenetics to develop treatments and whole genome sequencing to identify etiologies.

Development 189

Development Genome Genomics Medicine 189

Pharmaceutical Technology

FEBRUARY 23, 2023

In the last three years alone, there have been over 633,000 patents filed and granted in the pharmaceutical industry, according to GlobalData’s report on Artificial Intelligence in Pharmaceuticals: In-silico drug discovery. Adimab and Xencor are the other key patent filers of in-silico drug discovery.

Drugs 189

Drugs DNA In-Vivo In-Vitro 189

BioSpace

OCTOBER 31, 2022

Verge Genomics dosed its first patient in a Phase I trial studying VRG50635, while Stealth Bio's SBT-272 was granted Orphan Drug designation by the FDA.

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Genome Genomics Trials Drugs 75

Outsourcing Pharma

SEPTEMBER 3, 2024

Dr Dawn Thompson has over 20 years of experience in building technology platforms that leverage genomics at scale to produce novel products.

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Genome Genomics Drugs Production 109

Pharmaceutical Technology

FEBRUARY 13, 2023

Although recently approved drugs can treat seizures more safely, they do not treat the comorbidities that patients experience. With the latest advances in whole genome sequencing , it is increasingly clear that rare epilepsies are largely caused by a single genomic mutation, says Ferraro.

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Research Gene Gene Therapy Genomics 264

Bio Pharma Dive

APRIL 13, 2023

The startup says its genomics platform can improve on conventional sequencing by uncovering drug target vulnerabilities directly in patient tumor samples.

Genome 143

Genome Genomics Drugs 143

pharmaphorum

SEPTEMBER 16, 2022

Alphabet subsidiary and precision health company Verily recently announced a breakthrough in its AI drug discovery GPCR research collaboration with Sosei Heptares. Essentially, the collaboration brought together both “the right expertise and the right technology”, opening up myriad possibilities for targeting GPCRs within the human genome.

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Development Research Drugs Clinical Trials 135

Pharmaceutical Technology

APRIL 12, 2023

BMS says it expects the orally administered drug, which was granted breakthrough therapy designation in May 2022, to be approved in the second half of 2023. BMS acquired repotrectinib as part of its June 2022 acquisition of Turning Point Therapeutics.

Genome 130

Genome Genomics In-Vitro Gene 130

Pharmaceutical Technology

JUNE 23, 2022

Researchers at the University of New Hampshire (UNH) have found that a repurposed drug, CCG-50014, could hinder the activity of a key enzyme of the SARS-CoV-2 virus, which causes Covid-19. Utilising a currently available drug compound in a new way is called drug repurposing.

Drugs 130

Drugs Protein Genomics Genome 130

Scienmag

MARCH 31, 2021

Company accelerates commercialization efforts to address a million at-risk patients’ unmet needs Bluestar Genomics announces today it received U.S. Food and Drug Administration (FDA) Breakthrough Device designation for its proprietary noninvasive pancreatic cancer detection test in patients with new-onset diabetes.

Genome 75

Genome Genomics Development Drugs 75

pharmaphorum

DECEMBER 21, 2021

However, despite the work still left to be done, there are now a growing number of treatments in the pipeline and 2020 proved to be a remarkable year for orphan drug approvals, with the US FDA approving more orphan designated treatments than non-orphan drugs. The potential to leverage genomic data. Headway being made.

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Development Genome Genomics Drugs 98

pharmaphorum

JULY 8, 2022

The pharmaceutical industry is increasingly relying on artificial intelligence to power its drug discovery and development efforts, and its spend in this area has created a multibillion-dollar market for AI technologies. As it stands, the time needed for a drug to reach the market ranges from 12 to 18 years, with an average cost of about $2.6

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Drugs Clinical Development Marketing Genome 131