pharmaphorum

JULY 14, 2021

Eli Lilly bought a stake in Protomer Technologies and its glucose-sensing insulin platform last year, and it must like what it has seen in the programme since then – it has just agreed to buy the company outright. . It was also responsible for the first recombinant insulin product – Humulin – which launched in 1982 and remains on sale.

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Pharmaceutical Technology

JUNE 29, 2022

The pharmaceutical industry often relies on enzymes to perform a process known as biocatalysis, which facilitates the cost-effective and sustainable production of small molecule drugs at scale. In 2021, Novo Nordisk Pharmatech, a leading pharmaceutical-grade insulin and Quats product supplier announced plans to enter the enzyme market.

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Pharmaceutical Technology

APRIL 25, 2023

Amphastar is expected to make up to $450m in milestone payments based on sales of Baqsimi. Lilly launched the drug in 2019 to provide rescue treatment for diabetes patients who take insulin. Lilly launched the drug in 2019 to provide rescue treatment for diabetes patients who take insulin.

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Pharmaceutical Technology

APRIL 10, 2023

India-based pharmaceutical company Cipla has entered into a perpetual licence agreement with Swiss drugmaker Novartis Pharma for the diabetes drug Galvus and its combination brands. Furthermore, Galvus can be used in combination with other medicinal products such as insulin when unable to offer adequate glycaemic control.

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XTalks

MARCH 17, 2025

billion, primarily linked to initiating Phase III trials for petrelintide as a stand-alone therapy, with sales-based milestones that could push the total value to $5.3 Amylin, a hormone co-secreted with insulin, plays a key role in regulating appetite by enhancing leptins effects the hormone that signals fullness after eating.

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pharmaphorum

NOVEMBER 26, 2021

Novo Nordisk has said that the introduction of value-based procurement (VBP) for insulin products by the Chinese government will have an impact on its revenues next year. The VBP for insulin – which applies to supplies destined for hospitals in China – is expected to be implemented during the first half of 2022, according to Novo Nordisk.

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pharmaphorum

NOVEMBER 21, 2022

The company argues that the cost is justified as Tzield (teplizumab) is the first drug that can delay the onset of type 1 diabetes, fending off the time when they become highly reliant on insulins and at risk of the serious complications that can accompany advanced T1D. It also has an option on global marketing rights to the drug.

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pharmaphorum

JULY 7, 2021

Three months ago, the FDA said it was unconvinced by a bridging study designed to show equivalence between Provention’s product intended for commercial sale, made by contract manufacturer AGC Biologics, and the drug that teplizumab’s original developer Eli Lilly used in clinical trials.

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STAT News

NOVEMBER 17, 2022

The decision is a partial win for AbbVie, since its rheumatoid arthritis treatment has generated almost $200 billion in sales in nearly two decades. in 2023, giving prescription drug plans a chance to pit different suppliers against one another for discounts. Several competing biosimilar versions are set to debut in the U.S.

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Pharmaceutical Technology

MARCH 29, 2023

In September 2021, Bristol Myers Squibb in-licensed the first programme, EVT8683, after the successful filing of an investigative new drug (IND) application with the Food and Drug Administration (FDA). This programme has now proceeded into a Phase I clinical trial.

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pharmaphorum

JANUARY 28, 2021

In fact, because biosimilar adoption has accelerated in recent years, studies show that the United States is on track to reduce drug costs by $100 billion over the next five years. One of these markets is the insulin market. Currently, more than seven million patients rely on insulin, and that number is growing each year.

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Pharma in Brief

AUGUST 9, 2021

On July 31, 2021, Health Canada published a Notice of Intent outlining its plan to amend the Food and Drug Regulations ( FDR ) and the Medical Devices Regulations in the spring of 2022. The proposed amendments require applicants to provide the Minister with an RMP as part of their application for a drug authorization for human use.

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Drug Channels

MARCH 30, 2023

Humira sales would be decline by about 37% in 2023—which is at the lower end of its previous erosion projection of 35% to 55%. Our crazy drug channel led Amgen to launch both a high-list/high-rebate and a low-list/low-rebate version of the drug. d/b/a Drug Channels Institute. Much more to come.

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Drug Channels

SEPTEMBER 7, 2022

As regular readers know, the biosimilar boom for provider-administered drugs has been accelerating. In the video below, I review these developments and discuss lessons from the launch of Semglee, the first interchangeable insulin. That’s when Humira, the best-selling drug in the U.S., d/b/a Drug Channels Institute.

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Pharmaceutical Technology

APRIL 12, 2023

The additional possible $650 million supplementary payment would be given for “future development, regulatory, commercial and sales milestone payments per product, as well as tiered royalties on future product sales”. This venture into stem cell therapy will be Novo Nordisk’s next step in diversifying its diabetes drug portfolio.

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XTalks

NOVEMBER 3, 2022

Eli Lilly is finding itself in an enviable position with its newly launched diabetes injection Mounjaro (tirzepatide) and blockbuster diabetes med Trulicity due to temporary shortages of competitor Novo Nordisk’s diabetes drug Ozempic (semaglutide). million in global sales, more than double initial estimates of $81 million.

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XTalks

JULY 4, 2024

The pharma industry is poised for significant transformations in 2024, driven by groundbreaking drugs that have set new benchmarks in the industry. This blog delves into the top 30 drugs to watch in 2024, leveraging insights from their sales performance in 2023. billion DKK ($21.1 billion USD).

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pharmaphorum

AUGUST 6, 2020

Novo said that COVID-19 has begun to affect sales, with fewer new starts as a result of social distancing measures. The company’s diabetes care products saw an increase in sales during the second quarter, although this was offset by lower sales of insulin. This was on sales that were flat at 30 billion DKK ($4.77

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pharmaphorum

JANUARY 6, 2023

With the US economy teetering on a recession, sales and marketing budgets are expected to take a hit among businesses across sectors. On 14th November 2022, Eli Lilly apparently wrote on its Twitter account, “We are excited to announce insulin is free now.” New drug launches were delayed. Industry frustrations.

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pharmaphorum

FEBRUARY 28, 2022

billion deal to acquire a portfolio of drugs from Viatris, the parent of its longstanding partner Mylan, which will boost its position on the international stage. . Biosimilars are near-copies of complex biologic drugs that in trials have shown that they have the same safety and efficacy profile as the originator drug.

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pharmaphorum

JUNE 2, 2022

R&D into orphan drugs is growing alongside the number of approved treatments, providing treatments for rare diseases that previously did not have any. Evaluate Pharma’s recent Orphan Drug Report subtitled its overview of the market ‘Niche no longer.’ It is estimated that between 3.5

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Druggist

OCTOBER 4, 2020

Drug treatment can be used alongside lifestyle measures. Most of the drugs which are recommended in the symptomatic management of IBS can be purchased over the counter from pharmacies, supermarkets and online. IBS – drug therapy IBS medications are used for symptomatic management of the condition. Drugs to stop diarrhoea.

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Containment Pharmacy Bacteria Sales 98

pharmaphorum

MARCH 21, 2022

Provention is seeking approval of teplizumab as a treatment to delay clinical type 1 diabetes in at-risk individuals, hoping the drug can become the first disease-modifying therapy in these patients. In the latter, teplizumab wasn’t able to show an impact on insulin use or HbA1c, an indirect measure of glucose control over time.

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pharmaphorum

JANUARY 10, 2023

New drugs for immunological and inflammatory diseases feature prominently among new product launches this year that could top $1 billion in annual sales by 2027 or be clinical “game changers,” according to Clarivate.

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pharmaphorum

MAY 21, 2021

Eli Lilly has scored five out of five with its phase 3 trials of type 2 diabetes candidate tirzepatide, setting up regulatory filings for a drug that the drugmaker thinks could be the lynchpin of its franchise in the coming years. . Treatment with Lilly’s drug also resulted in a 11.7

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pharmaphorum

NOVEMBER 18, 2022

” T1D occurs when the immune system attacks and destroys the insulin-producing pancreatic beta cells that make insulin, and occurs in three stages. The post Provention finally gets FDA nod for type 1 diabetes drug teplizumab appeared first on.

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XTalks

JANUARY 25, 2023

Massachusetts-based TheracosBio has received US Food and Drug Administration (FDA) approval for diabetes med Brenzavvy (bexagliflozin) to help improve glycemic control in adults with type 2 diabetes. The drug is taken once a day in conjunction with diet and exercise. What is the Animal Drug Regulatory Process?

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XTalks

NOVEMBER 17, 2021

Good Idea claims the amino acids “prime” the metabolism to extract more energy from food, while the chromium picolinate boosts insulin sensitivity, minimizing the amount needed to deliver energy into cells. However, none of these claims have been evaluated by the US Food and Drug Administration (FDA).

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pharmaphorum

FEBRUARY 18, 2021

Drug prices to plummet in wave of expiring patents”. These are just three headlines that come up when you Google “drug patent expiry”. It’s no wonder “loss of exclusivity (LOE)” or “the patent cliff” is an ominous prospect for drug manufacturers – shrouded in the threat of job losses and falling share prices. billion in 2004.14

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Branding Insulin Sales FDA Approval 52

XTalks

JUNE 5, 2024

Dexcom’s Stelo continuous glucose monitor is the first over-the-counter (OTC) glucose biosensor to receive approval from the US Food and Drug Administration (FDA). Dexcom was the first to integrate CGM with insulin delivery devices, smartphone connectivity and the first to offer an alternative to fingersticks for treatment-related decisions.

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Drug Channels

SEPTEMBER 15, 2020

Last Friday, The Wall Street Journal published my opinion piece: The Federal Program That Keeps Insulin Prices High. I summarize issues with the role of contract pharmacies in the 340B Drug Pricing Program. My arguments will be familiar to regular readers of Drug Channels. d/b/a Drug Channels Institute.

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pharmaphorum

OCTOBER 19, 2021

Biosimilar competition to AbbVie’s big-selling Humira drug in the US has just been ratcheted up by the FDA approval of Boehringer Ingelheim’s Cyltezo – which can be substituted for the reference drug without any prescriber intervention.

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The Pharma Data

DECEMBER 28, 2020

Food and Drug Administration (“FDA”) has approved its Abbreviated New Drug Application (“ANDA”) for Glucagon for Injection Emergency Kit, 1 mg. This further highlights Amphastar’s considerable abilities to bring complex generic drugs to the market, and more specifically, our strong peptide capabilities.”

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Drug Channels

DECEMBER 16, 2020

This week, I’m rerunning some popular posts while I prepare for this Friday’s video webinar: Drug Channels Outlook 2021. In the meantime, please enjoy my op-ed from September, which focuses on how 340B warps *prescription* prices (not drug list prices) and patient out-of-pocket costs. d/b/a Drug Channels Institute.

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Roots Analysis

NOVEMBER 27, 2023

This capital infusion aligns with Novo Nordisk’s commitment to increasing production capacity for key drugs, including Ozempic for type 2 diabetes and the obesity therapy Wegovy, both based on the GLP-1 agonist semaglutide. billion (USD 2.3 billion) in expanding its manufacturing facility in Chartres, France. With this additional EUR 2.1

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Druggist

MAY 12, 2021

Celevac tablets were licensed as general sale list medicines (GSL), which means they could be sold in any retail outlet, including pharmacies, over the counter without a prescription. . What is Celevac? Celevac is a brand of tablets containing methylcellulose. Each Celevac tablet contained 500mg of methylcellulose. 2013;2013:610908.

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The Pharma Data

MAY 4, 2021

The ban on the importation, manufacture, packing, sale, supply, possession, administration or use of unapproved COVID-19 vaccines therefore applies to all other vaccines, as well as to parallel imports of Comirnaty. TGA lifts suspension of Tandem t:slim X2 insulin pump, with conditions. Medsafe Notice. . TGA Notice , More. .

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