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In first, FDA approves KRAS-blocking cancer drug from Amgen

Bio Pharma Dive

For decades, scientists have tried unsuccessfully to target the KRAS gene, which is often mutated in lung, colon and pancreatic cancers. Lumakras is the first drug proven effective.

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Scientists Think This Psychedelic Drug Could Help Treat Anorexia

AuroBlog - Aurous Healthcare Clinical Trials blog

The psychedelic drug psilocybin (as found in ‘magic’ mushrooms) has promising potential as a treatment for the eating disorder anorexia nervosa, according to new research that looked at its effects on an animal model of the condition.

Scientist 246
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Lilly reaches end of the road with long-studied Alzheimer’s drug

Bio Pharma Dive

Prior trial failures hadn’t halted testing of solanezumab, once Lilly’s top Alzheimer’s drug candidate. But its final study defeat may help scientists better understand how to target the brain disease.

Drugs 313
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Gladstone and UCSF scientists discover BET protein role in Covid-19

Pharmaceutical Technology

Gladstone Institute of Virology director Melanie Ott said: “It’s clear from our results that the BET drugs currently available are not suitable for Covid-19. But certain elements of these drugs could be adapted for future drug development.”.

Protein 278
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Roche licenses Sangamo’s technology for another shot at Alzheimer’s drugs

Bio Pharma Dive

Through a new deal, Roche has exclusive rights to Sangamo molecules designed to repress the gene that makes “tau,” a protein many scientists view as a main driver of Alzheimer’s.

Licensing 332
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Scientists discover non-invasive approach for cancer therapy

Pharmaceutical Technology

Scientists at the Northwestern University in Illinois, US, have discovered a non-invasive approach to isolate a tumour’s attack cells from blood, rather than from tumours. Scientists removed and processed melanoma tumours, and found tumour-infiltrating lymphocytes (TILs) within them.

Scientist 244
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Genentech takes up a deal to make ‘molecular glue’ drugs

Bio Pharma Dive

Targeted protein degradation has emerged as one of the more competitive areas of pharmaceutical research in recent years as scientists develop new ways to reach difficult-to-drug targets.

Drugs 274