Thu.May 16, 2024

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Lilly’s once-weekly insulin matches daily shots in late-stage tests

Bio Pharma Dive

The results, which showed Lilly’s drug was as effective at controlling blood sugar as standard injections, come as Novo Nordisk seeks approval for a competing once-weekly insulin.

Insulin 306
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Tracking the opioid lawsuit settlements amidst calls for oversight

Pharmaceutical Technology

The US National Opioid Settlement is distributing more than $54 billion to communities grappling with the opioid crisis.

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Investors put $400M into biotech licensing obesity drugs from China

Bio Pharma Dive

The biotech, tentatively named Hercules CM Newco, has rights to three incretin drugs discovered by Jiangsu Hengrui Pharmaceuticals, two of which are in clinical testing.

Licensing 356
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DN-1508052 by Shanghai De Novo Pharmatech for Melanoma: Likelihood of Approval

Pharmaceutical Technology

DN-1508052 is under clinical development by Shanghai De Novo Pharmatech and currently in Phase I for Melanoma.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Biogen, Ionis shelve ALS drug following study failure

Bio Pharma Dive

While results indicated the drug works as intended, it didn’t have enough of an effect on a protein that’s become integral to many ALS research programs.

Drugs 321
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KRAS inhibitors: The next frontier beckons

Pharmaceutical Technology

There has been several developments in the KRAS inhibitor space, shaping the KRAS inhibitors of the future.

More Trending

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INZ-701 by Inozyme Pharma for Pseudoxanthoma Elasticum (PXE or Gronblad Strandberg Syndrome): Likelihood of Approval

Pharmaceutical Technology

INZ-701 is under clinical development by Inozyme Pharma and currently in Phase II for Pseudoxanthoma Elasticum (PXE or Gronblad Strandberg Syndrome).

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Roche keeps pace in obesity drug field with early study data

Bio Pharma Dive

A drug Roche acquired in a buyout of Carmot Therapeutics and that works similarly to Zepbound helped people lose nearly 19% of their body weight in a Phase 1 trial.

Drugs 195
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Top 10 countries accounted for India’s 63% of Ayush and herbal products export in 2023-24

AuroBlog - Aurous Healthcare Clinical Trials blog

The top 10 destinations led by USA, Germany and Italy accounted for almost 63.3 per cent of India’s Ayush and herbal products during the fiscal year 2023-24. Exports to these 10 countries together stood at $412 million, with a growth of 5.

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Food Allergy Awareness Week 2024: How can new treatments target an unmet need?

Pharmaceutical Technology

IgGenix is planning to initiate a clinical trial later this year investigating its peanut allergy monoclonal antibody IGXN001.

Allergies 147
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Optimizing Clinical Supply Strategy: Navigating Challenges & Finding Your Ideal Model

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A Neuroscientist Explains How Your Brain Actually Thinks

AuroBlog - Aurous Healthcare Clinical Trials blog

Have you ever wondered how your brain creates thoughts or why something randomly popped into your head? It may seem like magic – but actually the brain is like a supercomputer inside your head that helps you think, learn and make decisions. Imagine your brain as a busy city with lots of streets and buildings.

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Takeda’s dengue vaccine obtains WHO prequalification

Pharmaceutical Technology

Takeda's new dengue vaccine, TAK-003, has received prequalification from the World Health Organization (WHO).

Vaccine 147
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May 16, 2024: Journal Peer Reviewers Are Familiar With Pragmatic Trials, Want More on Implementation

Rethinking Clinical Trials

According to a report from the NIH Pragmatic Trials Collaboratory Coordinating Center, journal editors and peer reviewers were familiar with pragmatic clinical trials and their designs and analytic approaches, but they often asked for more information about intervention implementation. The report was published this week in the Living Textbook of Pragmatic Clinical Trials.

Trials 147
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J&J to buy Proteologix and its dual-targeting antibody drugs for $850M

Bio Pharma Dive

The deal is part of a plan by J&J to build a portfolio of “differentiated” bispecific antibodies, an increasingly popular area of drug development.

Antibody 145
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The New Age of Decentralized Clinical Trials

White paper that delves into the complex topic of Decentralized Clinical Trials and how to master them within the confines of FDA Regulations

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Closed Loop and Pharmanovia investigate precision medicine combination in hypertension

Pharma Times

The OptiZest study aims to investigate a personalised dose of Zestril in these patients

Medicine 141
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JWTCR-001 by MediGene for Solid Tumor: Likelihood of Approval

Pharmaceutical Technology

JWTCR-001 is under clinical development by MediGene and currently in Phase I for Solid Tumor.

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Researchers develop ‘digital twin’ heart models to better monitor PAH NHS patients

Pharma Times

The cardiovascular disease, pulmonary arterial hypertension, affects around 6,500 people in the UK

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ABP-671 by Jiangsu Atom Bioscience and Pharmaceutical for Chronic Kidney Disease (Chronic Renal Failure): Likelihood of Approval

Pharmaceutical Technology

ABP-671 is under clinical development by Jiangsu Atom Bioscience and Pharmaceutical and currently in Phase I for Chronic Kidney Disease (Chronic Renal Failure).

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European Clinical Supply Planning: Balancing Cost, Flexibility and Time

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In Big Pharma's growth rankings, Lilly took top spot from Novo Nordisk in Q1

Fierce Pharma

The momentum the biopharma industry showed in the fourth quarter of 2023 has continued into this year. | The momentum the biopharma industry showed in the fourth quarter of 2023 has continued into this year. With 18 of the industry’s top 25 companies achieving year-over-year revenue gains, Q1 came close to matching the final quarter of last year, when 21 of the top 25 companies showed increases.

Drugs 124
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DN-1508052 by Shanghai De Novo Pharmatech for Prostate Cancer: Likelihood of Approval

Pharmaceutical Technology

DN-1508052 is under clinical development by Shanghai De Novo Pharmatech and currently in Phase I for Prostate Cancer.

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FDA snubs another China-made PD-1 with rejection of Elevar, Hengrui's liver cancer combo

Fierce Pharma

China-made PD-1 inhibitors just can’t get a clean pass through the FDA. | China-made PD-1 inhibitors continue to struggle at the FDA. This week, the U.S. agency rejected Elevar Therapeutics and Jiangsu Hengrui Pharma's PD-1 combination in liver cancer.

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DN-1508052 by Shanghai De Novo Pharmatech for Colorectal Cancer: Likelihood of Approval

Pharmaceutical Technology

DN-1508052 is under clinical development by Shanghai De Novo Pharmatech and currently in Phase I for Colorectal Cancer.

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The New Age of Decentralized Clinical Trials

This new white paper defines and details the impact of Decentralized Clinical Trials on the Pharmaceutical industry and how the impact can be measured along with steps companies can take to ensure adoption.

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12 Questions with Kirsten Parr

pharmaphorum

Get to know Kirsten Parr through 12 insightful questions as she shares her experiences and insights while working at IPG Health Medical Communications.

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DN-1508052 by Shanghai De Novo Pharmatech for Bladder Cancer: Likelihood of Approval

Pharmaceutical Technology

DN-1508052 is under clinical development by Shanghai De Novo Pharmatech and currently in Phase I for Bladder Cancer.

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Fire breaks out at Novo production hub: None injured and construction timelines likely unaffected, company says

Fierce Pharma

A fire broke out Thursday on the roof of a building under construction at Novo Nordisk’s key manufacturing hub in Kalundborg, Denmark, where the drugmaker is currently charting a multi-year expansi | A fire broke out Thursday on the roof of a building under construction at Novo Nordisk’s key manufacturing hub in Kalundborg, Denmark, where the drugmaker is currently charting a multi-year expansion to boost capacity for its blockbuster diabetes and obesity drugs.

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Patient access to medicines must be the focus of US drug pricing policy

Pharmaceutical Technology

Amidst congressional action and changes in payer pricing models, experts discuss what must be done for patients to reap benefits.

Medicine 130
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Unlocking Excellence: How Catalent Is Transforming Japan’s Clinical Research

Planning on running clinical trials in Japan? How can you reliably supply these studies? Discover Catalent’s clinical supply packaging facility in Shiga, Japan. Strategically located between Tokyo and Osaka, and one of largest in Japan, this 6,000 square meter facility offers comprehensive services including primary and secondary clinical packaging and labelling, comparator sourcing, cold chain storage, local and global distribution, local language support and white glove service to support stud

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FT US Pharma and Biotech Summit: Live coverage

pharmaphorum

Explore innovation, investment, and policies at the US Pharma and Biotech Summit 2024. Join industry leaders, regulators, and investors to discuss trends shaping healthcare.

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Roche targets obesity market with early positive trial data

Pharmaceutical Technology

Roche’s GLP-1/GIP receptor agonist, which was gained in the Carmot acquisition, showed an 18.8% weight loss in a Phase Ib trial.

Trials 130
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TIGIT developer iTeos raises $120m, and other financings

pharmaphorum

Notable biotech financings in the last week include a $120m direct offering for iTeos, and private rounds for Lycia, Attovia, Ajax, and CinDome

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Uniquity Bio launches with $300m and an MSD Phase II asset to boot

Pharmaceutical Technology

Uniquity is planning Phase II trials in COPD and asthma with TSLP-targeting drug solrikitug that it licensed from MSD

Licensing 130
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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.