Sun.May 05, 2024

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Exercising in Midlife May ‘Reverse’ Years of Inactivity, Large Study Finds

AuroBlog - Aurous Healthcare Clinical Trials blog

As the world’s aging population grows, and dementia, cardiovascular disease, and osteoporosis reach epidemic levels, people of all ages want to know how they can live healthier, not just longer, lives. For women in their 40s and 50s, it’s not too late to take action.

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Thick Liquids and Clinical Outcomes in Hospitalized Patients With ADRD and Dysphagia

JAMA Internal Medicine

This cohort study assesses whether thick liquids are associated with better clinical outcomes than thin liquids in hospitalized patients with Alzheimer disease and related dementias (ADRD) and oropharyngeal dysphagia.

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Indian medical care providers explore HCX platforms to reduce administrative tasks in insurance claims

AuroBlog - Aurous Healthcare Clinical Trials blog

Indian medical care providers are exploring Health Exchange (HCX) platforms for reducing administrative tasks in insurance claims. It maximises cloud computing, allowing access in real-time, and secure information related to insurance claims. It enables seamless interoperability of health claim data between different systems, whilst safeguarding sensitive medical information at all costs.

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Cytisinicline for Vaping Cessation in Adults Using Nicotine E-Cigarettes

JAMA Internal Medicine

This randomized clinical trial seeks to determine the efficacy and safety of cytisinicline vs placebo to produce abstinence from e-cigarette use in adults seeking to quit vaping nicotine.

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Optimizing Clinical Supply Strategy: Navigating Challenges & Finding Your Ideal Model

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Quest for Better Clinical Research Early Talent Hiring Practices a ‘Race That Never Ends’

ACRP blog

Stakeholders in the matter can best leverage cutting-edge options for overcoming the inadequacies of current early talent hiring practices in the clinical research industry if they approach the challenge with the attitude that “it’s not a marathon [to be won], it’s just a race that never ends,” in the words of one attendee of Friday’s (May 3) meeting of the ACRP Partners Advancing the Clinical Research Workforce ™ consortium at ACRP 2024 in Anaheim, Calif.

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Too Much Dentistry

JAMA Internal Medicine

This Viewpoint explores whether all dental procedures are clinically necessary given their expense and the disparate access to treatment among some socioeconomic and racial and ethnic groups.

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New patent expiration for Wyeth Pharms drug DUAVEE

Drug Patent Watch

Annual Drug Patent Expirations for DUAVEE Duavee is a drug marketed by Wyeth Pharms and is included in one NDA. It is available from two suppliers.

Drugs 59
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Gilead, Ipsen Tout Phase III Primary Biliary Cholangitis Data as PDUFA Dates Loom

BioSpace

Gilead Sciences’ primary biliary cholangitis candidate seladelpar and Ipsen’s PBC asset elafibranor both showed encouraging Phase III results Wednesday, as they face looming FDA decision dates.

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Thinning Evidence for Thickened Liquid Diets in Dementia and Dysphagia

JAMA Internal Medicine

Less is More

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Vir Seeks to Challenge Gilead With Phase II Hepatitis Delta Data

BioSpace

Vir Biotechnology reported Wednesday that its monoclonal antibody tobevibart, as a monotherapy and in combination with Alynylam-partnered elebsiran, achieved high rates of virologic response at week 24 in patients with chronic hepatitis delta.

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The New Age of Decentralized Clinical Trials

White paper that delves into the complex topic of Decentralized Clinical Trials and how to master them within the confines of FDA Regulations

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Which pharmaceutical companies have the most drug patents in Hong Kong?

Drug Patent Watch

This chart shows the pharmaceutical companies with the most patents in Hong Kong.

Drugs 102
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Lilly’s Zepbound Wins NICE Backing for Obese Patients With Very High BMI

BioSpace

The U.K.’s National Institute for Health and Care Excellence has endorsed the use of Eli Lilly’s Zepboundfor weight management in patients with BMI of 35 kg/m2 and above and at least one weight-related comorbidity.

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DEA Concurs: Marijuana Meets Schedule III Criteria

FDA Law Blog

By Larry K. Houck — The Associated Press reported on Tuesday following confirmation by five anonymous individuals with knowledge that the Drug Enforcement Administration (“DEA”) is moving to reschedule marijuana from schedule I to the less stringently controlled schedule III. US poised to ease restrictions on marijuana in historic shift, but it’ll remain controlled substance (Apr. 30, 2024).

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Viking Builds Case for NASH Hopeful With Histological Data

BioSpace

Viking Therapeutics’ nonalcoholic steatohepatitis candidate VK2809 significantly improved secondary histologic endpoints at 52 weeks with no worsening of fibrosis, as assessed by hepatic biopsy.

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European Clinical Supply Planning: Balancing Cost, Flexibility and Time

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FDA Adcomm Votes Against Lykos’ MDMA-Assisted PTSD Therapy

BioSpace

An FDA advisory committee on Tuesday overwhelmingly rejected Lykos Therapeutics’ investigational MDMA-assisted therapy for post-traumatic stress disorder due to safety concerns and how the company conducted its trials.

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The ABCs of Biopharma This Week: ASCO, BIO and Cancer

BioSpace

The biggest conferences of the year dominated news this week: the American Society of Clinical Oncology annual meeting and the BIO International Convention.

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Lilly’s Tirzepatide Shows Positive Phase II NASH Data, Tees Up Potential Expa.

BioSpace

More than 50% of nonalcoholic steatohepatitis patients treated with Eli Lilly’s tirzepatide saw at least a one-stage improvement in fibrosis, according to the pharma’s latest mid-stage readout.

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Companies to Watch for Potential M&As in 2024

BioSpace

Analysts predict a booming year for mergers and acquisitions, powered by obesity drug sales and pressure from upcoming patent expirations.

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The New Age of Decentralized Clinical Trials

This new white paper defines and details the impact of Decentralized Clinical Trials on the Pharmaceutical industry and how the impact can be measured along with steps companies can take to ensure adoption.