Thu.May 02, 2024

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Reunion raises over $100M to build a better psychedelic drug

Bio Pharma Dive

The funding will help Reunion pay for a mid-stage study testing its most advanced medicine — essentially a synthetic version of the hallucinogenic psilocin — in women with postpartum depression.

Medicine 311
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The top pharmaceutical companies by R&D expenditure

Pharmaceutical Technology

From Merck & Co to Sanofi, Pharmaceutical Technology lists the leading pharmaceutical companies spending the most on R&D in 2023.

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Delphia starts up with $67M to make a new type of cancer drug

Bio Pharma Dive

Delphia is developing medicines designed to overstress certain cellular pathways to the point tumor cells die, an approach the biotech calls “activation lethality.

Medicine 310
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Novo Nordisk aims for market domination, boasts $1.5bn obesity sales in Q1

Pharmaceutical Technology

Novo Nordisk noted a 22% boost in sales owing to increased sales of GLP-1 agonists and other obesity products.

Sales 246
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Novartis to buy Mariana Oncology in radiopharmaceutical expansion

Bio Pharma Dive

The $1 billion dollar acquisition will add to Novartis’ pipeline of the targeted radiation drugs, giving it a potential lung cancer treatment.

Drugs 288
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Xyphos and Poseida to develop allogeneic cell therapies for cancer

Pharmaceutical Technology

Xyphos Biosciences and Poseida Therapeutics have signed a deal to develop new allogeneic cell therapies for treating cancer.

More Trending

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Common Blood Pressure Drug Increases Lifespan And Slows Aging in Animals

AuroBlog - Aurous Healthcare Clinical Trials blog

The hypertension drug rilmenidine has been shown to slow down aging in worms, an effect that in humans could hypothetically help us live longer and keep us healthier in our latter years. Previous research has shown rilmenidine mimics the effects of caloric restriction on a cellular level.

Drugs 216
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BridgeBio spinout launches with $200M for KRAS cancer drugs

Bio Pharma Dive

The company, BridgeBio Oncology Therapeutics, has one drug in the clinic and hopes to soon advance two other candidates.

Drugs 182
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CDSCO empowers regulators & boosts exports through comprehensive training programmes

AuroBlog - Aurous Healthcare Clinical Trials blog

In a concerted effort to fortify regulatory capabilities and enhance pharmaceutical exports, the Central Drugs Standard Control Organisation (CDSCO) has orchestrated a series of impactful training initiatives in the fiscal year 2023-24.

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Moderna ends gene editing alliance with Metagenomi

Bio Pharma Dive

Metagenomi said the companies’ decision to part ways followed a “strategic prioritization” undertaken by Moderna, which has made several investments in gene editing research in recent years.

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Optimizing Clinical Supply Strategy: Navigating Challenges & Finding Your Ideal Model

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Biotechs face upward battle with recruiting patients on obesity trials

Pharmaceutical Technology

As the obesity space becomes more congested, clinical trial recruitment has become a larger issue for small biotechs.

Trials 147
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Nova’s Xromi approved in UK and EU for vaso-occlusive complications of SCD

Pharma Times

The inherited disorder is caused by genetic mutations that affects haemoglobin production

Genetics 128
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ESCMID 2024: Drug resistance in fungi – a growing issue

Pharmaceutical Technology

Emerging research from the ESCMID Global 2024 conference suggests that antifungal resistance, a global issue, is on the rise.

Drugs 130
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Facing pricing pressure from Lilly's Zepbound, Novo Nordisk scales Wegovy supply

Fierce Pharma

Novo Nordisk is facing fierce competition from Eli Lilly’s obesity rival Zepbound, which has shaken up U.S. pricing dynamics for the Danish company's popular GLP-1 drug. | Novo Nordisk is facing fierce competition from Eli Lilly’s obesity rival Zepbound, which has shaken up U.S. pricing dynamics for the Danish company's popular GLP-1 drug.

Drugs 124
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The New Age of Decentralized Clinical Trials

White paper that delves into the complex topic of Decentralized Clinical Trials and how to master them within the confines of FDA Regulations

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M&A revival with a 71% increase in billion-dollar transactions in Q1 2024

Pharmaceutical Technology

Mergers and acquisitions (M&As) in the biopharmaceutical industry involving companies developing drugs showed a 20% increase in total deal volume in the first quarter (Q1) of 2024 compared to Q1 2023, according to leading data and analytics company GlobalData’s Pharma Intelligence Center Deals Database.

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Study reveals vitamin D-altered mouse gut bacteria provides better cancer immunity

Pharma Times

Bacteroides fragilis in the gut improves immunity and immunotherapy treatment responses

Bacteria 124
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Emergent cuts 300 jobs and shuts down two facilities in cost-cutting drive

Pharmaceutical Technology

The operational changes are expected to save the biotech and manufacturing organisation $80m annually.

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Pace, acceleration, and precision are the name of the game

pharmaphorum

Security and privacy within biotech are critical points of consideration and discussion as the industry continues to innovate at speed, and it is such aspects that are central to today’s podcast with Zach Powers, chief information security officer at Benchling, the R&D cloud platform for the biotech industry.

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European Clinical Supply Planning: Balancing Cost, Flexibility and Time

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Novartis acquires Mariana in $1.75bn deal to strengthen radioligand portfolio 

Pharmaceutical Technology

Under the terms of the deal, Mariana will receive $1bn and up to $750m in additional milestone payments from Novartis.

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Mobile app guides patients through surgical recovery

pharmaphorum

Hospital staff in the UK have developed and piloted an app that can help patients monitor their progress to recovery after surgeries.

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MacroGenics gets grant for patent granted for compounds targeting IL23a and BAFF

Pharmaceutical Technology

Discover how MacroGenics Inc's patent for compounds targeting IL23A and BAFF offers a groundbreaking method for suppressing inflammatory responses. Learn about the specific polypeptide compositions and nucleic acids involved.

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As Imbruvica bows out, AstraZeneca clinches early Calquence win in newly diagnosed MCL

Fierce Pharma

As AbbVie and Johnson & Johnson’s Imbruvica retreated, AstraZeneca’s Calquence has become the first BTK inhibitor to claim a unique win in previously untreated mantle cell lymphoma (MCL). | AstraZeneca is touting a earlier-than-expected positive readout for Calquence in first-line mantle cell lymphoma. But a big question remains whether it can immediately file with the FDA, especially given the precedent of Imbruvica.

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The New Age of Decentralized Clinical Trials

This new white paper defines and details the impact of Decentralized Clinical Trials on the Pharmaceutical industry and how the impact can be measured along with steps companies can take to ensure adoption.

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Agenus gets grant for monoclonal antibodies targeting TIM-3 for treating subjects

Pharmaceutical Technology

Discover how Agenus Inc's groundbreaking patent for antibodies targeting TIM-3 is revolutionizing therapeutic antibody development. Explore the specific amino acid sequences and methods for efficient antibody production.

Antibody 130
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RNA glioblastoma vaccine shows promise in first human trial

pharmaphorum

A personalised vaccine for the aggressive brain cancer glioblastoma developed has shown encouraging signs of efficacy in its first human trial.

RNA 115
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Astellas Pharma gets grant for novel carbocyclic prolinamide derivatives for treating age-related macular degeneration

Pharmaceutical Technology

Discover Astellas Pharma's patented carbocyclic prolinamide derivatives for treating eye diseases like macular degeneration. Explore the unique compound structure and potential applications in pharmaceuticals and beyond.

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Unravelling the impact of ICH E6(R3) on Good Clinical Practice

pharmaphorum

The updated ICH E6(R3) Good Clinical Practice guidelines are here - discover what's changed and how clinical trials will need to adapt. This in-depth post unravels the key impacts of E6(R3).

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Unlocking Excellence: How Catalent Is Transforming Japan’s Clinical Research

Planning on running clinical trials in Japan? How can you reliably supply these studies? Discover Catalent’s clinical supply packaging facility in Shiga, Japan. Strategically located between Tokyo and Osaka, and one of largest in Japan, this 6,000 square meter facility offers comprehensive services including primary and secondary clinical packaging and labelling, comparator sourcing, cold chain storage, local and global distribution, local language support and white glove service to support stud

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BioCryst Pharmaceuticals gets grant for inhibitors of the complement system for disease treatment

Pharmaceutical Technology

Discover how BioCryst Pharmaceuticals' patent for complement system inhibitors offers groundbreaking treatment options for various diseases.

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Educating on the rewards of a career in life sciences

pharmaphorum

Pursue your passion for science with a rewarding career in life sciences. Learn how a job in biology, biotech, or health sciences offers intellectual stimulation and the chance to improve lives.

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Vertex Pharmaceuticals gets grant for treatment of alpha-1 antitrypsin deficiency with compound of formula (i)

Pharmaceutical Technology

Discover Vertex Pharmaceuticals' groundbreaking patent for compounds treating alpha-1 antitrypsin deficiency. Explore formula (I) derivatives and tailored compositions for precision medicine.

Medicine 130
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Moderna gears up for potential RSV vaccine launch this fall after better-than-expected first quarter

Fierce Pharma

With Moderna’s COVID-19 sales on the backfoot following the switch to an endemic vaccine market, the Massachusetts-based biopharma is busy laying the groundwork for its next potential mRNA shot in | Moderna currently expects initial approvals of its RSV vaccine to start rolling in during the first half of 2024, the company said Thursday. In turn, the company is eyeing a potential U.S. launch in the fall, which would capitalize on its established commercial efforts in the seasonal COVID-19 immuni

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.