Wed.Nov 13, 2024

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Pfizer considers divestiture of hospital drugs business

Pharmaceutical Technology

Pfizer is currently assessing the potential divestiture of its hospital drugs unit, a division mainly focused on antibiotics and sterile injectables used in hospitals and clinics, Reuters reported.

Drugs 246
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BioNTech to buy Biotheus, gaining control of cancer bispecific

Bio Pharma Dive

Biotheus’ antibody drug targets PD-L1 and VEGF, a design that’s high on drugmakers’ radars after the success of Summit Therapeutics’ ivonescimab over Keytruda.

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Running Through Life with Type 1 Diabetes

Worldwide Clinical Trials

By; Brooke Kaplan, Director, People Partner- HR Compliance & Human Capital Initiatives In April 2007, at 19 years old, I was a sophomore at the University of Maryland. I had always been relatively healthy, exercised recreationally, and worked part-time at the campus gym. I’d just returned from spring break at Disney World with my boyfriend (now husband), Zak, and we were gearing up for the Jewish holiday of Passover.

Insulin 162
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Amgen shares sink on obesity drug concerns; AstraZeneca to spend $3.5B on manufacturing

Bio Pharma Dive

An analyst note raising questions about Amgen’s MariTide triggered a stock sell-off Tuesday. Elsewhere, Roche and Novartis struck drug discovery deals.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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November 13, 2024: Pragmatic Trial of Smartphone Nudges to Prevent Distracted Driving, in This Week’s PCT Grand Rounds

Rethinking Clinical Trials

In this Friday’s PCT Grand Rounds, Kit Delgado of the University of Pennsylvania will present “Pragmatic Randomized Trial of Smartphone-Based Nudges to Reduce Distracted Driving Among US Auto Insurance Customers.” The Grand Rounds session will be held on Friday, November 15, 2024, at 1:00 pm eastern. Delgado is an associate professor of emergency medicine and epidemiology at the University of Pennsylvania and the director of the Penn Medicine Nudge Unit, which “designs an

Trials 173
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TRex Bio raises $84M to compete in crowded immune drug field

Bio Pharma Dive

The California biotech has drawn partnerships with Eli Lilly and J&J on the promise of its approach to rebalancing the immune system.

Drugs 182

More Trending

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Metsera raises $215M to accelerate obesity drug plans

Bio Pharma Dive

With promising Phase 1 results in hand, Metsera hopes to develop a longer-lasting GLP-1 injection along with other types of obesity treatments.

Drugs 162
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Syros stock craters after lead cancer therapy flops in Phase III trial

Pharmaceutical Technology

The company plans to discontinue the study after the combination therapy failed to meet the primary endpoint in the Phase III trial.

Trials 130
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23andMe to lay off more than 200 employees amid business struggles

Bio Pharma Dive

The genetic testing firm will also close its drug development arm. CEO Anne Wojcicki said the cuts are necessary to “focus on the long-term success of our core consumer business.

Genetics 130
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Intercept loses Ocaliva FDA full approval bid in rare liver disease

Pharmaceutical Technology

Intercept’s US president Vivek Devaraj said the pharma company still believes in the evidence supporting the liver disease treatment.

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Optimizing Clinical Supply Strategy: Navigating Challenges & Finding Your Ideal Model

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Lilly unwraps detailed data showing tirzepatide kept nearly 99% of prediabetic patients diabetes-free over 3 years

Fierce Pharma

Lilly unwraps detailed data showing tirzepatide kept nearly 99% of prediabetic patients diabetes-free over 3 years fkansteiner Wed, 11/13/2024 - 14:37

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The development of novel drugs: the role of lyophilization

Pharmaceutical Technology

Lyophilization plays a crucial role in successful biologic molecule development, but what is lyophilization – and how can it be mastered?

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Merck’s Pimicotinib Shows Promise in Expanding TGCT Options

XTalks

Merck KGaA recently shared positive results from its Phase III MANEUVER trial on pimicotinib, an investigational oral therapy for tenosynovial giant cell tumor (TGCT). TGCT is a rare, aggressive joint condition caused by overactive colony-stimulating factor 1 (CSF-1). A generally non-cancerous growth that forms in the tissue lining the joints, tendons or fluid-filled sacs around joints, TGCT often leads to abnormal joint tissue growth, painful swelling and stiffness.

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Health Canada approves GSK’s Ojjaara for myelofibrosis in anaemia patients

Pharmaceutical Technology

Health Canada has granted approval for GlaxoSmithKline’s (GSK) Ojjaara (momelotinib) for treating myelofibrosis (MF) in adults with moderate-to-severe anaemia.

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The New Age of Decentralized Clinical Trials

White paper that delves into the complex topic of Decentralized Clinical Trials and how to master them within the confines of FDA Regulations

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Microbiotica begins human trials for ulcerative colitis treatment

Pharma Times

First patient dosed in phase 1b trial of MB310 therapy

Trials 119
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Ontada and Datavant partner to boost oncology data access

Pharmaceutical Technology

Ontada has entered into a strategic partnership with health data platform Datavant to enable quick access to oncology insights.

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AstraZeneca and Merck's Koselugo delivers phase 3 trial win in adults with NF1, teeing up filings

Fierce Pharma

Four years after winning an FDA approval for Koselugo to treat children with the rare disorder neurofibromatosis type 1 (NF1), AstraZeneca is touting a trial result that could allow the company and | Four years after scoring an FDA approval to treat children with NF1, AstraZeneca says its Merck-partnered Koselugo has shown promise in adults.

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J&J sues US government for halting 340B rebate plan

Bio Pharma Dive

The pharma is trying to win court backing to pay hospitals rebates for two drugs in the 340B drug discount program, instead of offering upfront discounts.

Drugs 113
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European Clinical Supply Planning: Balancing Cost, Flexibility and Time

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Vivolta and Neurochase to produce brain therapy catheters

Pharma Times

New long-term partnership to address neurological disorder treatments

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AI helps with more precise surgery

pharmaphorum

AI technology is revolutionising the field of surgery by aiding in more precise and accurate diagnoses. Learn how AI is transforming the future of healthcare.

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How GE HealthCare’s SIGNA MAGNUS 3.0T Transforms Neuroimaging

XTalks

GE HealthCare’s SIGNA MAGNUS 3.0T magnetic resonance imaging (MRI) system, a head-only MRI scanner designed specifically for advanced neuroimaging, has been cleared by the US Food and Drug Administration (FDA). Unlike traditional whole-body MRI scanners, the SIGNA MAGNUS is tailored exclusively for imaging the brain and central nervous system (CNS), focusing on capturing intricate details required in neuroscience and clinical diagnostics.

Radiology 104
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Navigating new risks: How China’s Anti-Espionage Law could impact pharmaceutical supply chains

pharmaphorum

Explore the implications of China's Anti-Espionage Law on pharmaceutical supply chains and learn how businesses can navigate new risks effectively.

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The New Age of Decentralized Clinical Trials

This new white paper defines and details the impact of Decentralized Clinical Trials on the Pharmaceutical industry and how the impact can be measured along with steps companies can take to ensure adoption.

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The decentralized clinical trials market will grow to $25 billion by 2032

Outsourcing Pharma

Driven by the effects of the COVID-19 pandemic, the market for decentralized clinical trials has seen a push that will lead it to more than triple in size within the next decade.

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London "is number one European city in life sciences"

pharmaphorum

London is the top city in Europe for the life sciences industry, and ranks third worldwide after Boston and New York in the US, says MedCity report

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Transparency and remote options key in clinical trial engagement

Outsourcing Pharma

A recent Lindus Health survey emphasizes the importance of patient-centered designs in clinical trials, particularly highlighting how telehealth options could improve accessibility and convenience for participants.

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BioNTech buys Biotheus and its Keytruda rival for $950m

pharmaphorum

BioNTech buys Biotheus and its Keytruda rival for $950m Phil.

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Unlocking Excellence: How Catalent Is Transforming Japan’s Clinical Research

Planning on running clinical trials in Japan? How can you reliably supply these studies? Discover Catalent’s clinical supply packaging facility in Shiga, Japan. Strategically located between Tokyo and Osaka, and one of largest in Japan, this 6,000 square meter facility offers comprehensive services including primary and secondary clinical packaging and labelling, comparator sourcing, cold chain storage, local and global distribution, local language support and white glove service to support stud

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The decentralized clinical trials market will grow to $25 billion by 2032

Outsourcing Pharma

Driven by the effects of the COVID-19 pandemic, the market for decentralized clinical trials has seen a push that will lead it to more than triple in size within the next decade.

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Amgen plays down safety concern with obesity candidate

pharmaphorum

Amgen has rebuffed claims made by an analyst suggesting that its obesity drug MariTide is associated with reductions in bone mineral density

Drugs 88
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US companies enhancing decentralized clinical trials

Outsourcing Pharma

Traditional clinical trials usually rely on several physical trial sites to recruit and monitor patients.

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Ali Parsa is back in digital health with startup Quadrivia

pharmaphorum

Former Babylon Health founder and CEO Ali Parsa is back with new venture Quadrivia and Qu, an AI tool to support clinician decision-making

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.