Fri.Feb 07, 2025

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An unexpected mechanism regulates the immune response during parasitic infections

Medical Xpress

Researchers at the University of Lige (Belgium) have uncovered a previously unknown mechanism that regulates the immune response against parasites. During a parasitic infection, specific immune cells, known as virtual memory T cells, become activated and express a surface molecule called CD22, which prevents an excessive immune reaction. This discovery could help in better-controlling inflammation and improving immune responses to infections.

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Bain Capital buys Mitsubishi Tanabe Pharma for $3.3bn

Pharmaceutical Technology

Bain Capital said its decision to buy Mitsubishi Tanabe is due to the strong growth potential of Japans healthcare industry.

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Tariffs raise concern among generic drugmakers, as advocacy groups seek exemptions

Bio Pharma Dive

“There is not a single member of AAM who has not raised concerns about the tariff situation,” said the CEO of the generic drug lobby Association for Accessible Medicines.

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Sanofi increases ownership stake partaking in pharma buyback trend

Pharmaceutical Technology

Sanofi has agreed to purchase its own shares worth 2bn ($2.08bn), part of a $5.1bn share buyback initiative in 2025.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva Health Inc.

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Immune drugmakers Alumis and Acelyrin to merge

Bio Pharma Dive

The two biotechs, which have lost most of their share value following lucrative IPOs, are combining in a deal that leaves the new company with a bigger cash balance and three drugs in testing.

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Treating alcohol addiction: filling the medication gap

Pharmaceutical Technology

With Dry January firmly behind us, many adults are prompted to reassess their relationship with alcohol. Alcohol Change, the UK charity behind the popular Dry January initiative, found that 30% of men and 26% of women in the UK wished to reduce the amount of alcohol they drank in 2024.

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Relmada acquires Tourette’s therapy rights from Asarina

Pharmaceutical Technology

Relmada has acquired complete ownership rights to Sepranolone, developed for Tourette syndrome (TS) from Asarina Pharma.

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Pharma and Biotech IPOs in 2025: Emerging Market Trends

XTalks

An initial public offering (IPO) is the process through which a private company sells its shares to the public for the first time, transitioning into a publicly traded entity. In the biotechnology sector, a biotech IPO occurs when a biotech firm lists its shares on a stock exchange, thereby attracting investment from public markets. This move not only raises funds from a wider pool of investors but also secures the essential capital needed to drive R&D.

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Alumis and Acelyrin sign merger agreement

Pharmaceutical Technology

Alumis and Acelyrin have announced a definitive merger agreement, which will result in an all-stock transaction.

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Scientists discover mitochondria's role in shaping memory circuits

Medical Xpress

Virginia Tech neuroscientists have uncovered a mitochondrial process that supports the brain cells critical for learning, memory, and social recognition.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Dr Reddy’s and Shanghai Henlius sign agreement for HLX15

Pharmaceutical Technology

Dr Reddy's Laboratories has signed a licence agreement with Shanghai Henlius Biotech to develop and commercialise HLX15.

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SANSA Home Sleep Apnea Test Gets a New Upgrade — No Apps, No Bluetooth

XTalks

The FDA has cleared Huxley Medicals SANSA home sleep apnea test for cellular data upload, eliminating the need for Bluetooth pairing or smartphone apps. This update removes a common hurdle in home sleep testing connectivity issues allowing test results to be transmitted automatically without manual setup. Traditional home sleep tests often rely on Bluetooth syncing, which can lead to incomplete tests or lost data.

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How AI is streamlining cell and gene therapy manufacturing

Pharmaceutical Technology

AI could deliver substantially greater efficiencies in cell and gene therapy manufacturing and enable more patients to benefit.

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Today’s Rare Disease Launches Require the Right Specialty Pharmacy Partner

Drug Channels

Todays guest post comes from Richard Faris, Chief Strategy & Growth Officer at PANTHERx Rare Pharmacy. Richard outlines the key factors for commercialization success when a manufacturer launches treatments for rare and orphan diseases. He explains the key considerations for choosing a specialty pharmacy network design, selecting the right pharmacy partners, and establishing patient services HUBs.

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Optimizing Clinical Supply Strategy: Navigating Challenges & Finding Your Ideal Model

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43rd Annual JP Morgan Healthcare Conference 2025 OR

Pharmaceutical Technology

Deals, pipeline updates and geopolitical issues drove the conversation at the 2025 JP Morgan Healthcare conference.

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Flu season in the US is the most intense it's been in at least 15 years

Medical Xpress

The U.S. winter virus season is in full force, and by one measure is the most intense in 15 years.

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FDA starts review of first bronchiectasis drug candidate

pharmaphorum

The FDA has started a priority review of Insmed's brensocatib, which is pitching to become the first approved therapy for bronchiectasis in the US.

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CDC posts, then deletes, data on bird flu

Medical Xpress

Scientists are calling on the U.S. Centers for Disease Control and Prevention (CDC) to disclose data about the risks of bird flu to people and pets that was posted briefly online Wednesday and quickly deleted.

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The New Age of Decentralized Clinical Trials

White paper that delves into the complex topic of Decentralized Clinical Trials and how to master them within the confines of FDA Regulations

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Bain buys Japanese pharma Mitsubishi Tanabe for $3.4bn

pharmaphorum

Bain Capital has agreed to buy Mitsubishi Tanabe for around $3.

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Weakness in lung cancer's defenses found—an enzyme that boosts cancer cell metabolism

Medical Xpress

Lung cancer is a particularly challenging form of cancer. It often strikes unexpectedly and aggressively with little warning, and it can shapeshift in unpredictable ways to evade treatment.

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M&A in Pharma: Balancing Growth and Risk

Pharmaceutical Commerce

What factors should be consideredand how can both parties benefit long-term?

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Co-located cell types help drive aggressive brain tumors, study finds

Medical Xpress

A type of aggressive, treatment-resistant brain tumor has a distinct population of immune cells that support its growth, according to new research led by investigators at the Johns Hopkins Kimmel Cancer Center Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns Hopkins University School of Medicine.

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European Clinical Supply Planning: Balancing Cost, Flexibility and Time

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Velocity’s Staszow, Poland, Site Recognized as Leading Global Enroller for Phase 3 Trial

Velocity Clinical Research

Congratulations to our team in Staszw, Poland, and Katarzyna Wawrzyniec-Lis, MD, for being the top global enroller for Boehringer Ingelheims Phase 3 cardiovascular safety study for patients with obesity! Velocity is supporting this study at more than 20 sites across the U.S., Poland, and Germany. The post Velocity’s Staszow, Poland, Site Recognized as Leading Global Enroller for Phase 3 Trial appeared first on Velocity Clinical Research.

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UK govt bans 'bird gatherings' as avian flu outbreak worsens

Medical Xpress

The UK government announced Friday an imminent ban in England on "bird gatherings" such as fairs, markets and shows, seeking to stop the spread of a highly contagious avian influenza.

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Breaking Point: How 2025 Will Reshape Patient Support Services

Pharmaceutical Commerce

From matrix programs to anti-abandonment strategies, predictions for a new era.

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Study links heavy cannabis use to higher death risk, psychosis

Medical Xpress

Heavy weed use may be far more dangerous than people realize, according to a pair of studies published in JAMA Network Open.

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The New Age of Decentralized Clinical Trials

This new white paper defines and details the impact of Decentralized Clinical Trials on the Pharmaceutical industry and how the impact can be measured along with steps companies can take to ensure adoption.

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JP Morgan Week 2025 – Phil Johnson

pharmaphorum

Stay tuned for an exclusive video interview with Phil Johnson from JP Morgan Week 2025, where he shares insights and perspectives on the future of finance and technology.

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Concentrations of selected PFAS up in firefighters after 2023 Maui wildfires

Medical Xpress

Maui County firefighters involved in the response to the 2023 Maui wildfires had higher median summed concentrations of some perfluoroalkyl and polyfluoroalkyl substances (PFAS) than other responders, according to research published in the Feb. 6 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Investigating the Unwinding of Continuous Medicaid Coverage During the COVID-19 Pandemic

Pharmaceutical Commerce

A cohort study investigates the magnitude of lost coverage among pediatric patients, following the conclusion of the pandemic public health emergency.

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3D bioprinting technology could lead to personalized gastric cancer treatment

Medical Xpress

A collaborative research team from POSTECH has successfully developed a gastric cancer model using 3D bioprinting technology and patient-derived cancer tissue fragments. This innovative model preserves the characteristics of actual patient tissues and is expected to rapidly evaluate and predict individual patient drug responses. The research has been published in the journal Advanced Science.

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Unlocking Excellence: How Catalent Is Transforming Japan’s Clinical Research

Planning on running clinical trials in Japan? How can you reliably supply these studies? Discover Catalent’s clinical supply packaging facility in Shiga, Japan. Strategically located between Tokyo and Osaka, and one of largest in Japan, this 6,000 square meter facility offers comprehensive services including primary and secondary clinical packaging and labelling, comparator sourcing, cold chain storage, local and global distribution, local language support and white glove service to support stud