Sun.Apr 14, 2024

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EMA finds no suicide risk with GLP-1 diabetes, obesity drugs

pharmaphorum

EMA review finds no link between GLP-1 agonists used to treat diabetes and obesity and thoughts of suicide or self-injury.

Drugs 109
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5 Promising MASH Therapies That Could Follow Madrigal’s Rezdiffra

BioSpace

Metabolic dysfunction-associated steatohepatitis experts welcomed Madrigal’s Rezdiffra as an “important first," but there are more mid- to late-stage therapies showing promising results.

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Acute Cardiac Events Among Hospitalized Older Adults With RSV Infection

JAMA Internal Medicine

This cross-sectional study examines the frequency and severity of acute cardiac events in hospitalized adults aged 50 years or older with respiratory syncytial virus infection.

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4 Investigational Weight Loss Drugs That Could Change the Market

BioSpace

GLP-1 treatments are all the rage in this space, but they aren’t the only approach in development. The pipeline assets highlighted here offer a differentiated approach, potentially increasing efficacy or reducing side effects.

Marketing 105
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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SGLT2i vs Sulfonylureas for Gout Prevention Among Patients With Type 2 Diabetes Receiving Metformin

JAMA Internal Medicine

This cohort study uses target trial emulation to evaluate risk of incident gout and rate of recurrent gout flares in patients with type 2 diabetes initiating sodium-glucose cotransporter-2 inhibitors (SGLT2i) vs sulfonylurea.

Trials 61
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AbbVie Touts Long-Term Efficacy of Qulipta as Preventive Migraine Treatment

BioSpace

AbbVie’s small molecule drug Qulipta has durable benefits and can reduce migraine frequency through 48 weeks of follow-up, according to interim Phase III data released on Friday.

Drugs 93

More Trending

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Patented AI Platform Identifies Promising Early-Stage BioPharma Assets and Companies

BioSpace

Fierce competition. Thin pipelines. Patent cliffs. The stakes are sky-high for pharmaceutical companies and investors alike.

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New patent expiration for Takeda Pharms drug DEXILANT SOLUTAB

Drug Patent Watch

Annual Drug Patent Expirations for DEXILANT+SOLUTAB Dexilant Solutab is a drug marketed by Takeda Pharms Usa and is included in one NDA. There are six patents protecting this drug.

Drugs 59
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Listen Up: Emerging Vocal Biomarker Could Aid ALS Drug Development

BioSpace

Experts are hopeful that objective biomarker measures for amyotrophic lateral sclerosis, such as the ones being developed by EverythingALS, will lead to more targeted, effective treatments.

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New patent expiration for Astrazeneca Ab drug FARXIGA

Drug Patent Watch

Annual Drug Patent Expirations for FARXIGA Farxiga is a drug marketed by Astrazeneca Ab and is included in one NDA. It is available from five suppliers.

Drugs 59
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Optimizing Clinical Supply Strategy: Navigating Challenges & Finding Your Ideal Model

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Regeneron Launches $500M Venture Capital Fund Skewed Toward Biotech

BioSpace

While the VC fund launched on Monday by Regeneron Pharmaceuticals has an investment mandate that includes healthcare broadly, Regeneron Ventures will lean towards biotechnology, devices, tools and enabling technologies.

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New patent for Norton Waterford drug QVAR REDIHALER

Drug Patent Watch

Annual Drug Patent Expirations for QVAR+REDIHALER Qvar Redihaler is a drug marketed by Norton Waterford and is included in one NDA. It is available from three suppliers.

Drugs 59
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Genentech Walks Away From $3B Allogeneic T-Cell Pact with Adaptimmune

BioSpace

Roche’s Genentech subsidiary is terminating for undisclosed reasons its 2021 contract with Adaptimmune for the development of allogeneic T-cell therapeutics.

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New patent for Astrazeneca drug TAGRISSO

Drug Patent Watch

Annual Drug Patent Expirations for TAGRISSO Tagrisso is a drug marketed by Astrazeneca and is included in one NDA. It is available from one supplier.

Drugs 59
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The New Age of Decentralized Clinical Trials

White paper that delves into the complex topic of Decentralized Clinical Trials and how to master them within the confines of FDA Regulations

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FDA Adcomm Backs New Surrogate Endpoint for Accelerated Approvals in Blood Ca.

BioSpace

An FDA advisory committee on Friday agreed that using minimal residual disease could be a viable surrogate endpoint for accelerated approval for drug development in multiple myeloma.

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New patent for Azurity drug EPRONTIA

Drug Patent Watch

Annual Drug Patent Expirations for EPRONTIA Eprontia is a drug marketed by Azurity and is included in one NDA. It is available from one supplier.

Drugs 59
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FDA Puts Clinical Hold on Neumora’s Schizophrenia Drug Due to Preclinical Saf.

BioSpace

Following cases of convulsions in rabbits in a preclinical study, the FDA has placed a clinical hold on Neumora Therapeutics’ Phase I schizophrenia drug candidate NMRA-266.

Drugs 65
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Drug Patent Expirations for the Week of April 14, 2024

Drug Patent Watch

DEXILANT (dexlansoprazole) Takeda pharms usa Patent: 8,722,084 Expiration: Apr 15, 2024 See More … For more information on how DrugPatentWatch can help with your pharmaceutical business intelligence needs, contact admin@DrugPatentWatch.

Drugs 59
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European Clinical Supply Planning: Balancing Cost, Flexibility and Time

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Electronic Health Record Population Health Management for Chronic Kidney Disease Care

JAMA Internal Medicine

This cluster randomized clinical trial examines the effectiveness of an electronic health record–based population health management intervention vs usual care for reducing chronic kidney disease progression.

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Which pharmaceutical companies have the most drug patents in New Zealand?

Drug Patent Watch

This chart shows the pharmaceutical companies with the most patents in New Zealand.

Drugs 52
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Roche Bispecific T-Cell Engager Improves Survival in Lymphoma, Teeing up Label Expansion

BioSpace

Roche said Monday that its bispecific T cell engager Columvi improved survival in a Phase III lymphoma trial, clearing the drugmaker to seek a full, expanded label that could drive sales growth.

Sales 45
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Adverse Pregnancy Outcomes and Long-Term Mortality in Women

JAMA Internal Medicine

This cohort study aims to determine long-term mortality risks associated with 5 major adverse pregnancy outcomes in a large population-based cohort of women.

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The New Age of Decentralized Clinical Trials

This new white paper defines and details the impact of Decentralized Clinical Trials on the Pharmaceutical industry and how the impact can be measured along with steps companies can take to ensure adoption.