Thu.Mar 13, 2025

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MeiraGTx spins Parkinson’s, obesity gene therapies into AI startup

Bio Pharma Dive

The joint venture with generative AI firm Hologen hands MeiraGTx $200 million up front as well as other financial perks — a “transformative” deal, according to the company’s CEO.

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Grand Rounds March 7, 2025: A Trial of a “Kidney Action Team” for Hospitalized Patients with Acute Kidney Injury (F. Perry Wilson, MD MSCE)

Rethinking Clinical Trials

Speaker F. Perry Wilson, MD MSCE Associate Professor of Medicine and Public Health Director, Clinical and Translational Research Accelerator Yale University New Haven, CT Slides Keywords Electronic Alerts; Acute Kidney Injury; Action Team Key Points Acute Kidney Injury (AKI), or abrupt decline in kidney function, is common, affecting about 15% of hospitalized patients.

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Mallinckrodt, Endo to combine in $7B deal

Bio Pharma Dive

The merger will give the combined entity the financial flexibility to pursue drug licensing deals and broaden its therapeutic focus, executives said on a conference call.

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Emergent signs financial investment agreement with Swiss Rockets

Pharmaceutical Technology

Emergent has entered a strategic financial investment agreement with Swiss Rockets to support the latters biotech portfolio.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Medical Device & MedTech Layoffs in 2025: A Roundup

XTalks

In 2025, as market pressures intensify and companies refocus on core strategic priorities, medical device and medtech companies have been forced to make tough decisions regarding their workforces. These developments come amid a broader nationwide trend of workforce realignment, with both private and public entities, including the FDA’s recent rehires amid mass layoffs, adapting to ongoing pressures.

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Mallinckrodt and Endo sign $6.7bn merger deal

Pharmaceutical Technology

The two companies are merging after previously filing for bankruptcy due to opioid-related litigation and financial losses.

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More Trending

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Gedeon Richter’s once-daily endometriosis pill approved for NHS use

Pharmaceutical Technology

NICE estimates that 1,000 women could benefit from Ryeqo, which can be taken once-daily up until the menopause.

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Addressing supply chain challenges for biosimilar products

Drug Patent Watch

Navigating the Complex World of Biosimilar Supply Chains As the demand for biosimilars continues to grow, so do the challenges associated with their supply chains. From manufacturing and quality control to distribution and regulatory compliance, the stakes are high for pharmaceutical companies looking to bring these life-changing treatments to market.

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Vivace closes $35m in Series D for cancer drug development

Pharmaceutical Technology

Vivace Therapeutics has closed $35m in a Series D financing round to support the clinical development of its cancer drug VT3989.

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The revolutionary impact of understanding genomics

Drug Discovery World podcast

This is the latest episode of the free DDW narrated podcast, titled The revolutionary impact of understanding genomics, which covers two articles written for DDW Volume 24 Issue 3, Summer 2023. They are called: Open science, genomics, and the quiet revolution in our approach to pharma and Junk DNA: How the dark genome is changing RNA therapies .

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Optimizing Clinical Supply Strategy: Navigating Challenges & Finding Your Ideal Model

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Telix’s new lead-212 generator could dispel medical isotope scalability hurdles

Pharmaceutical Technology

Whilst showing promise in cancer therapies, lead-212-based alpha emitters are hard to commercially supply.

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AI With A Human Touch: Ensuring Authenticity in AI Marketing

Intouch Solutions

The rise of artificial intelligence (AI) has transformed the marketing landscape, enabling brands to personalize content, optimize campaigns, and reach audiences more efficiently than ever before. However, as AI-generated content becomes increasingly commonplace, a pressing concern has emergedhow can brands maintain authenticity and trust in a world where 71% of consumers worry about the legitimacy of AI content?

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Atsena’s ATSN-201 gains FDA fast track status for XLRS treatment

Pharmaceutical Technology

Atsena Therapeutics has received fast track designation from the FDA for ATSN-201, aimed at treating X-linked retinoschisis (XLRS).

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Grifols clinical trial shows positive results for post-polio patients

Pharma Times

Immunoglobulin therapy improves mobility in phase 2/3 study

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The New Age of Decentralized Clinical Trials

White paper that delves into the complex topic of Decentralized Clinical Trials and how to master them within the confines of FDA Regulations

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Vivani treats first patient with long-lasting drug implant for weight loss

Pharmaceutical Technology

A day after announcing a business split-off to focus on weight loss and diabetes implants, Vivani Medical has implanted the first patient with its device.

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Rxulti approved in the European Union for adolescent schizophrenia

Pharma Times

EC extends brexpiprazole indication to include adolescents

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Kelun-Biotech first to bag TROP2 approval in lung cancer

pharmaphorum

Kelun-Biotech wins first global regulatory approval, in China, for a TROP2-directed antibody-drug conjugate (ADC) in lung cancer

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Syngene Purchases First US Manufacturing Facility for $36.5M

Pharmaceutical Commerce

The CRDMOs acquisition of the Baltimore plant is expected to boost its biologics presence.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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'Transformational' pill for endometriosis gets NHS nod

pharmaphorum

Around 1,000 women in England a year with endometriosis will soon have access to the first daily oral therapy, Gedeon Richter's Ryeqo, via the NH

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How Sonicu supports remote clinics and pharmacists with a 24/7 cloud-based remote monitoring solution

Pharmaceutical Commerce

A pharmacy director leverages the simplicity of the Sonicu installation system to deliver affordable temperature monitoring and deploys the mobile app to dozens of employees at clinics across Illinois. Responding to a loss of drugs after a freezer failure, the team at KSB also upgraded their Board of Pharmacy audit readiness.

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Insilico raises $110m for AI-designed drug pipeline

pharmaphorum

Insilico Medicine has raised $110 million in Series E funding for its artificial intelligence-powered drug discovery operations

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Sonicu and Pharmacy Stars help hospital-based pharmacy with a powerful software integration

Pharmaceutical Commerce

Temperature Monitoring provider Sonicu and compounding compliance software provider Pharmacy Stars help hospital-based pharmacies with a powerful integration that improves compliance workflow and data collection

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Rumour confirmed as Mallinckrodt merges with Endo

pharmaphorum

Two companies forced to file for bankruptcy protection due to opioid litigation in the US Mallinckrodt and Endo have agreed to join forces via a $6.7 billion merger.

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Hancock Health Case Study: Pharmacy Temperature Monitoring

Pharmaceutical Commerce

A regional hospital serving suburban Indianapolis, Hancock Regional Hospital faced a familiar challenge: disparate monitoring systems that taxed their staff and too many manual processes that drove inefficiencies. CEO Steve Long greenlit a solution: a consolidated temperature, environmental, and sound monitoring program that protected precious assets, automated tedious compliance, and freed up staff from the tedious work of manual logging.

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Is Mallinckrodt about to merge with Endo?

pharmaphorum

Two pharmas that filed for bankruptcy protection due to opioid litigation in the US Mallinckrodt and Endo are rumoured to be in merger talks.

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Learn how the pharmacy leader at one of the midwest’s largest retail pharmacy operation improved compliance while protecting their temperature-sensitive drugs

Pharmaceutical Commerce

Transitioning from manual temperature logs and reactive power outage management to a comprehensive cloud-based monitoring solution, Discount Drug Mart has revolutionized its approach to pharmacy operations and compliance. Adopting Sonicu's advanced system, this Ohio-based retail pharmacy chain now benefits from seamless temperature monitoring and real-time power outage alerts across its 77 locations.

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2022 Research: The Rapid Rise of Ocean Freight Visibility

A research study conducted by The Journal of Commerce and FourKites surveyed hundreds of international shippers, exploring how their usage of global supply chain visibility technology has evolved since the onset of global disruptions caused by COVID-19. For international shippers, ocean freight visibility has evolved from optional to essential and satisfaction with visibility varies greatly depending on how it is obtained and delivered.

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LinkedIn Posts

Client Pharma

The post LinkedIn Posts appeared first on ClientPharma.

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Sonicu serves scores of hospital-based, specialty and retail pharmacies with our simple and affordable temperature and environmental monitoring

Pharmaceutical Commerce

Learn how easy and affordable it can be to adopt a wireless remote temperature and environmental monitoring system that can protect your vital temperature-sensitive assets while automating tedious compliance

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Regulators vs weight loss ads: Time to rethink the rules?

pharmaphorum

In the world of weight loss ads, regulators are questioning the rules as direct-to-consumer ads for drugs like Ozempic, Wegovy, and Zepbound flood the market. Is it time to rethink the regulations?

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Navigating Internal Constraints and Uncertainty

Pharmaceutical Commerce

In the second part of his video interview with Pharma Commerce Editor Nicholas Saraceno, Brad Stewart, BDOs national life sciences co-leader, outlines the internal constraints that CFOs are reporting as their biggest manufacturing obstacle, along with other hurdles they are encountering.

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European Clinical Supply Planning: Balancing Cost, Flexibility and Time