Mon.Jul 08, 2024

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Understanding the Patient Journey: Overcoming Barriers to Enrolling Depression Clinical Trials

Worldwide Clinical Trials

By: Lisle Kingery, PhD, Therapeutic Strategy Lead, Neuroscience With depression rates at an all-time high and limited new treatments available, depression clinical trials are more important than ever. In a mental health disorder laden with patient enrollment barriers due to the indication’s symptoms, as well as many situational and social factors, how does a sponsor ensure their drug development program enrolls an adequate number of participants in a timely manner?

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Lilly to buy Morphic in $3B bet on inflammation drug

Bio Pharma Dive

The deal would hand Lilly an experimental pill that could one day rival Takeda's blockbuster medicine Entyvio as a treatment for inflammatory bowel disease.

Medicine 301
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Myricx Bio gains $114m in Series A round to develop NMTi-ADCs

Pharmaceutical Technology

Myricx Bio has secured £90m ($114m) in its Series A financing round to propel its NMTi-ADC therapeutics into the clinical development stage.

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A London biotech raises $114M to hone a new ADC payload

Bio Pharma Dive

Myricx Bio is developing a type of payload that it thinks could work in tumors resistant to the toxins contained in ADCs like Enhertu and Trodelvy.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva Health Inc.

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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GSK and MVV launch malaria medicine in Brazil and Thailand

Pharmaceutical Technology

GSK and MMV have announced the launch of tafenoquine to prevent the relapse of P. vivax malaria in Brazil and Thailand.

Medicine 256
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HilleVax’s norovirus vaccine ineffective in large trial of infants

Bio Pharma Dive

Shares in HilleVax plummeted after the company reported its experimental shot failed to meet the primary and secondary goals of the Phase 2b study.

Vaccine 274

More Trending

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Ligand to buy Apeiron; Roche reports another TIGIT setback

Bio Pharma Dive

Acquiring Apeiron will hand Ligand rights to royalties on sales of the neuroblastoma drug Qarziba. Elsewhere, Aerovate said it’s considering strategic alternatives and CSL reported a notable milestone.

Sales 270
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NIPERs need to establish comprehensive ecosystem for entrepreneurship: DoP study

AuroBlog - Aurous Healthcare Clinical Trials blog

The National Institutes of Pharmaceutical Education and Research (NIPERs) need to establish more comprehensive ecosystem that includes mentorship, support for incubation, funding methods, and industrial alliances to promote entrepreneurship in the pharmaceutical sector, which can also substantially help these institutes to foster self-reliance, according to a study.

Research 238
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Coloplast launches digital leakage notification system Heylo for stoma patients

Pharma Times

More than 176,000 people in the UK are living with a stoma, according to NHS data

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Find It Hard to Focus? You May Have Cognitive Disengagement Syndrome

AuroBlog - Aurous Healthcare Clinical Trials blog

Do you find that you daydream a lot? Are you often sluggish and tend to disengage easily when doing a task? You might have cognitive disengagement syndrome, or CDS.CDS was first described by psychologists in the 1960s and 1970s when they noticed that some people display these traits more persistently than others.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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UK pharma group reprimands Novo Nordisk for undisclosed payments

Pharmaceutical Technology

The Association of the British Pharmaceutical Industry (ABPI) also called out Novartis, Pfizer, and Otsuka for breaching its code.

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Mission awarded $5.2m to advance potential Parkinson’s treatment

Pharma Times

The progressive neurodegenerative condition affects around 153,000 people in the UK

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China’s NMPA approves Antengene’s XPOVIO for DLBCL

Pharmaceutical Technology

China's NMPA approved Antengene’s new indication of XPOVIO for adults with relapsed or refractory diffuse large B-cell lymphoma.

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Lilly's Mounjao triggers more weight loss than Novo Nordisk's Ozempic: study

Fierce Pharma

Is Eli Lilly’s Mounjaro or Novo Nordisk’s Ozempic more effective in helping patients lose weight? | Is Eli Lilly’s Mounjaro or Novo Nordisk’s Ozempic more effective in helping patients lose weight? While a head-to-head trial pitting the two treatments remains ongoing, new evidence shows that Lilly’s tirzepatide may be the superior weight loss product.

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Optimizing Clinical Supply Strategy: Navigating Challenges & Finding Your Ideal Model

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Ascentage Pharma’s olverembatinib approved in Macau for leukaemia

Pharmaceutical Technology

Ascentage Pharma has obtained approval for its new BCR-ABL1 TKI, olverembatinib, in Macau for haematological malignancy indications.

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Study finds GLP-1 drugs may cut obesity-related cancers

pharmaphorum

GLP-1 agonists like Novo Nordisk's Ozempic reduce the risk of 10 of 13 cancers associated with obesity in an observational study.

Drugs 114
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Merck puts 1,000-plus Zostavax lawsuits to bed after plaintiffs file for dismissal

Fierce Pharma

After a drawn-out litigation process, Merck & Co. seems to have finally washed its hands of more than a thousand lawsuits tied to its shingles vaccine Zostavax. | A U.S. appeals court has tossed a request to resurrect certain lawsuits claiming Merck’s popular shot Zostavax caused patients to develop shingles. The court made its decision after the plaintiffs filed a voluntary dismissal some two years after logging a loss in Pennsylvania.

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Lilly scores against Novo Nordisk in weight loss contest

pharmaphorum

An observational study has suggested that Lilly’s tirzepatide is better at achieving weight loss than Novo Nordisk's semaglutide

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The New Age of Decentralized Clinical Trials

White paper that delves into the complex topic of Decentralized Clinical Trials and how to master them within the confines of FDA Regulations

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CDMO Lotte breaks ground on $3.3B production plant in Korea, touts growth goals

Fierce Pharma

After announcing plans last year to expand manufacturing in its home country, Korean CDMO newcomer Lotte Biologics has kicked off work on a sprawling facility along Incheon’s waterfront near Seoul. | Late last week, Lotte Biologics broke ground on its flagship facility at the Songdo Bio Campus in Incheon International City, South Korea. The company is pitching the production effort as a key part of its quest to become one of the top 10 CDMOs in the world.

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Lilly swoops on Morphic to claim IBD drug candidate

pharmaphorum

Eli Lilly boosts its inflammatory bowel disease pipeline with a $3.

Drugs 111
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Novo's Ozempic, Wegovy linked to potential eye problem? Not so fast, analysts say

Fierce Pharma

Novo Nordisk’s massively successful GLP-1 analog semaglutide, the active ingredient in the popular diabetes and obesity meds Ozempic and Wegovy, may be linked to a vision loss disorder, a new | Novo Nordisk’s popular GLP-1 analog semaglutide may be linked to a vision loss disorder, a study suggests. But one team of analysts cautioned against reading too much into the analysis.

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Myricx raises £90m after pivot to ADCs for cancer

pharmaphorum

Myricx Bio taps into the red-hot interest in companies working on antibody-drug conjugates (ADCs) for cancer, raising £90m in its Series A

Antibody 111
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European Clinical Supply Planning: Balancing Cost, Flexibility and Time

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Lilly Pays $3.2B to Buy Morphic and Deepen Immunology, Gastro Portfolio

BioSpace

Eli Lilly on Monday announced a $3.2 billion all-cash deal to purchase Morphic and its pipeline of oral integrin therapies in a move to expand the pharma’s presence in the autoimmune diseases space.

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Healthcare report finds declining public trust in institutions

pharmaphorum

A recent healthcare report conducted by Edelman reveals a concerning trend of declining public trust in healthcare institutions. Explore the key findings and implications in this comprehensive analysis.

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Grifols Gets $6B Takeover Offer from Founding Family, Brookfield to Go Private

BioSpace

The blood plasma medicines manufacturer is considering a buyout offer from the founding family and asset manager Brookfield, which would delist the company from the Spanish and Nasdaq markets.

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As IARC uprates talc cancer risk, will J&J be affected?

pharmaphorum

IARC has published a new assessment of talc’s potential to cause cancer, concluding that is it ‘probably carcinogenic’ to humans

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The New Age of Decentralized Clinical Trials

This new white paper defines and details the impact of Decentralized Clinical Trials on the Pharmaceutical industry and how the impact can be measured along with steps companies can take to ensure adoption.

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With Boehringer ruling, industry extends legal losing streak against Medicare price negotiations

Fierce Pharma

As the process surrounding Medicare's drug price negotiations rolls on this summer—and as the pharmaceutical industry continues to loudly voice its complaints—another lawsuit contesting the legal v | Boehringer Ingelheim joins AstraZeneca, J&J and Bristol Myers Squibb in having a case challenging Medicare price negotiations fail to bear fruit.

Drugs 92
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Could Spain’s Grifols be heading for de-listing?

pharmaphorum

The family that owns Spanish pharma Grifols and private equity firm Brookfield may take the company private in a deal worth around €5.

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Roche to reintroduce eye implant med Susvimo 2 years after recall

Fierce Pharma

Roche's launch of eye implant Susvimo was stopped short in 2022 after manufacturing concerns led to a market withdrawal. Now, with the FDA’s blessing to reintroduce the therapy, the | The company is reintroducing the therapy after receiving the FDA's blessing for updates made to the device, ending a two-year voluntary recall.

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GLP-1s May Cut Risk of 10 Obesity-Related Cancers in Diabetes Patients: Study

BioSpace

GLP-1 receptor agonists could reduce the risk of 10 obesity-associated cancers, such as meningioma, multiple myeloma and colorectal cancer, in type 2 diabetes patients, according to an analysis of electronic health records.

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Unlocking Excellence: How Catalent Is Transforming Japan’s Clinical Research

Planning on running clinical trials in Japan? How can you reliably supply these studies? Discover Catalent’s clinical supply packaging facility in Shiga, Japan. Strategically located between Tokyo and Osaka, and one of largest in Japan, this 6,000 square meter facility offers comprehensive services including primary and secondary clinical packaging and labelling, comparator sourcing, cold chain storage, local and global distribution, local language support and white glove service to support stud