Mon.Apr 15, 2024

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Reimagining CRO Partnerships: The Emerging Preference for Midsize Organizations

Worldwide Clinical Trials

As the clinical research landscape continually evolves, the choice of a Contract Research Organization (CRO) partner can significantly impact the success of drug development programs. In fact, recent industry dynamics indicate a considerable shift in preference towards midsize CROs, driven by the need for more personalized, agile, and cost-effective partnerships.

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Ultragenyx says Angelman therapy is working, but safety questions remain

Bio Pharma Dive

Treatment appeared to result in functional and cognitive gains in people with the neurological disorder. Three participants experienced lower extremity weakness, however.

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Francis Crick researchers reveal pathways linking intestinal inflammation and colitis

Pharma Times

Affecting over 500,000 people in the UK, IBD comprises Crohn’s disease and ulcerative colitis

Research 150
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Roche reports survival data for new dual-acting lymphoma drug

Bio Pharma Dive

The results could give Roche’s Columvi an edge over a rival medicine from AbbVie and Genmab, while Regeneron awaits an approval of its own therapy.

Medicine 287
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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva Health Inc.

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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ImmunityBio gets grant for cross-reactive SARS-COV2 vaccine composition for multiple coronaviruses

Pharmaceutical Technology

Discover ImmunityBio Inc's groundbreaking patent for a cross-reactive SARS-CoV2 vaccine targeting multiple variants. Learn how this innovative method boosts immune response and memory cells for enhanced protection.

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Keeping cleanrooms clean: Choosing the right laboratory equipment is key

Bio Pharma Dive

Because live cell and tissue products are extremely sensitive to contamination from microorganisms, viral particles or other airborne impurities, research and manufacturing involving these materials needs to be conducted in a cleanroom environment.

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The growing role for cfHPV-DNA testing in OPSCC therapeutic development

Bio Pharma Dive

Learn about why access to robust biomarkers such as cfHPV-DNA is pivotal in determining eligibility, assessing treatment response and detecting recurrence early to improve patient outcomes.

DNA 264
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The cutting-edge monitoring technology that is transforming the future of clinical trials

Pharmaceutical Technology

Pharmaceutical innovations require an extra layer of precision and care in the supply chain process.

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Regeneron commits $500M to new venture capital fund

Bio Pharma Dive

While corporate venture arms are commonplace among pharmaceutical companies, the new fund announced Monday is Regeneron’s first.

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Marinus fails to meet early stopping criteria for status epilepticus trial

Pharmaceutical Technology

The future development of IV ganaxolone will be determined by results from the Phase III RAISE study, expected in summer 2024.

Trials 130
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Neumora’s schizophrenia drug hit with clinical hold

Bio Pharma Dive

Shares of the biotech dipped by double digits following disclosure the FDA had paused an early-stage study of Neumora’s muscarinic-targeting drug.

Drugs 173
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Soligenix bags orpan drug designation for Marburg virus vaccine

Pharmaceutical Technology

Soligenix’s Marburg virus vaccine demonstrated 100% protection in non-human primates in a clinical study.

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Psychedelic treatments on cusp of approval, but questions remain

pharmaphorum

Psychedelic treatments for conditions like PTSD using substances like MDMA are on the brink of approval, but there are still unanswered questions surrounding their effectiveness and potential risks. Learn more here.

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Genzyme gets grant for method for reducing interference in drug assay due to antibodies

Pharmaceutical Technology

Discover Genzyme Corp's innovative method for detecting anti-drug antibodies in human body fluids. Learn how their patented process reduces interference in drug assays effectively.

Antibody 130
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Optimizing Clinical Supply Strategy: Navigating Challenges & Finding Your Ideal Model

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Regeneron launches $500m venture capital arm

pharmaphorum

Regeneron has formed a corporate venture capital unit with $100 million a year to invest over the next five years in “biopharmaceutical, healthcare, and health technology” start-ups.

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Ginkgo BioWorks gets grant for AAV vector for treating NPC1 with specific gene sequence

Pharmaceutical Technology

Discover the groundbreaking gene therapy patent by Ginkgo BioWorks Inc for treating NPC1 using AAV vectors. Learn how this innovative approach offers hope for rare genetic disorders like Neimann-Pick Disease Type C.

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Activist hedge fund seeks big shake-up at Novavax

pharmaphorum

Shah Capital has fired a broadside at the management team of Novavax, seeking a change in leadership at the vaccine company and the appointment of two handpicked directors to the board. In an open letter, the hedge fund accuses Novavax’s leadership of squandering its “many significant competitive advantages and sizeable market opportunity” due to “self-inflicted problems” under the current team led by chief executive John Jacobs.

Vaccine 111
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Zydus Lifesciences gets grant for oral suspension pharmaceutical composition of immunosuppressive agent

Pharmaceutical Technology

Discover the innovative patent by Zydus Lifesciences Ltd for a pharmaceutical composition in oral suspension form, enhancing stability and palatability for immunosuppressive agents.

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The New Age of Decentralized Clinical Trials

White paper that delves into the complex topic of Decentralized Clinical Trials and how to master them within the confines of FDA Regulations

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After ph3 win, Roche eyes earlier use of Columvi in DLBCL

pharmaphorum

Roche’s CD20xCD3 bispecific antibody Columvi has improved survival when used as a second-line therapy for diffuse large B-cell lymphoma (DLBCL) in a phase 3 trial, setting up regulatory filings for earlier use of the drug in the treatment pathway.

Antibody 110
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Ablynx gets grant for inhibiting tumor growth by administering polypeptides binding gitr

Pharmaceutical Technology

Enhance immune response and inhibit tumor growth with Ablynx NV's patented immunoglobulin single variable domains targeting GITR. Explore the potential for cancer treatment and pharmaceutical compositions.

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The New Authenticity: SXSW 2024 Insights, Part 2

Intouch Solutions

At SXSW 2024, amidst a confluence of marketing, technology, AI, and design, one word seemed to echo through every conversation, panel, and workshop: authenticity. It’s fascinating, isn’t it? The idea of being genuine, real, and true — qualities so deeply sought after in everything we do, yet so complex and rich when we pause to unpack them. Among the minds at EVERSANA INTOUCH, with leaders spanning the spectrum from Strategic Planning to Creative Direction, and from Experience Design to Customer

Marketing 105
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Arena Pharmaceuticals gets grant for treatment of atopic dermatitis with compound 1

Pharmaceutical Technology

Discover the groundbreaking patent by Arena Pharmaceuticals for treating atopic dermatitis with a specific compound in a standard dose. Learn how (R)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid can revolutionize dermatological treatments.

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European Clinical Supply Planning: Balancing Cost, Flexibility and Time

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Advancing medicine requires more secure supply chains

pharmaphorum

The advancement of medicine is dependent on secure pharmaceutical supply chains. Discover why ensuring the security of these chains is crucial for the development and distribution of life-saving medications.

Medicine 105
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Ferring International Center gets grant for pharmaceutical composition for treating inflammatory bowel disease using bacteriophages

Pharmaceutical Technology

Discover a groundbreaking pharmaceutical composition with patented bacteriophages targeting E. coli strains in treating inflammatory bowel disease. Explore the innovative approach to combatting infections caused by adherent-invasive E. coli.

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Healthware re-launches as Eversana Intouch full service affiliate

pharmaphorum

Life sciences service provider (and pharmaphorum parent company) Eversana has completed the integration of Healthware Group, the Italy-based global agency and consultancy it acquired in October. The group will now be known as Eversana Intouch Healthware and will operate as Eversana’s sixth full-service affiliate.

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Allscripts Healthcare Solutions gets grant for resource management system for medical software applications optimization

Pharmaceutical Technology

Optimize and distribute predictively processed data in medical software applications with Allscripts Healthcare Solutions Inc's patented resource management system. Enhance operational capabilities and capacities for improved performance.

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The New Age of Decentralized Clinical Trials

This new white paper defines and details the impact of Decentralized Clinical Trials on the Pharmaceutical industry and how the impact can be measured along with steps companies can take to ensure adoption.

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Trial Findings for Minimally Invasive Parafascicular Technology Show Promise for Intracerebral Hemorrhage Treatment

Pharmaceutical Commerce

Results of the trial suggest that early intervention for intracerebral hemorrhage using parafascicular surgery were safe.

Trials 105
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AVEO Pharmaceuticals gets grant for decreasing blood urea nitrogen levels in hyperuricemia using anti-gdf15 antibody

Pharmaceutical Technology

Discover a groundbreaking method to treat renal disorders with AVEO Pharmaceuticals Inc's patented anti-GDF15 antibody. Learn how this innovative approach targets hyperuricemia and CKD for improved renal function.

Antibody 130
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Pharma Pulse 4/15/24: Increase in ransomware attacks to healthcare's remote access systems, The Health and Healthcare of Gen Xers & more

Pharmaceutical Commerce

The latest news for pharma industry insiders.

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Study warns of chronic kidney disease timebomb

pharmaphorum

Up to one in six people in eight industrialised nations could be suffering from chronic kidney disease (CKD) by 2032, with dire consequences for “patients, [the] planet, and economies,” says a new study.

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Unlocking Excellence: How Catalent Is Transforming Japan’s Clinical Research

Planning on running clinical trials in Japan? How can you reliably supply these studies? Discover Catalent’s clinical supply packaging facility in Shiga, Japan. Strategically located between Tokyo and Osaka, and one of largest in Japan, this 6,000 square meter facility offers comprehensive services including primary and secondary clinical packaging and labelling, comparator sourcing, cold chain storage, local and global distribution, local language support and white glove service to support stud