Tue.Nov 26, 2024

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Top 10 Cancer Drugs to Watch in 2024 Based on Recent Sales Data

XTalks

As oncology continues to dominate the pharmaceutical market, the global demand for effective cancer therapies has reached unprecedented levels. With advances in precision medicine and immunotherapy driving innovation, leading oncology drugs are not only transforming treatment paradigms but also generating billions in revenue. The year 2023 was no exception, with several cancer drugs achieving remarkable sales milestones, reflecting their efficacy, expanding indications and the growing global can

Sales 105
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November 26, 2024: Hybrid Methods Improve Collection of Patient-Reported Outcome Measures in Rural and Underserved Populations

Rethinking Clinical Trials

In an article published online this week , leaders from the NIH Pragmatic Trials Collaboratory share lessons learned about the collection of patient-reported outcome measures (PROMs) in medically underserved patients, including people with incomes below the federal poverty threshold, racial or ethnically minoritized groups, and rural and frontier communities.

Trials 144
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Alector turns to layoffs as Alzheimer’s drug fails

Bio Pharma Dive

The brain drug developer is letting go of around 41 of its 238 employees, in a move the company says will help “align resources” with its strategic priorities.

Drugs 276
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BridgeBio’s Attruby (Acoramidis): A New, More Potent TTR Stabilizer for ATTR-CM

XTalks

The US Food and Drug Administration (FDA) has approved Attruby (acoramidis) , marking a significant advancement for patients with transthyretin-mediated amyloid cardiomyopathy (ATTR-CM). This progressive disease occurs when misfolded transthyretin (TTR) proteins form amyloid deposits in the heart, leading to cardiac dysfunction. Attruby offers a near-complete stabilization of TTR — over 90 percent — halting the formation of amyloid fibrils that cause tissue damage and addressing the underlying p

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva Health Inc.

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Roche’s TIGIT-targeting drug for cancer fails its biggest test

Bio Pharma Dive

Long-awaited results released Tuesday showed adding tiragolumab to Roche's immunotherapy Tecentriq did not extend survival in a closely followed Phase 3 study called SKYSCRAPER-01.

Drugs 261
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Gilead adds investigational HIV vaccine to its portfolio from Spanish biotech   

Pharmaceutical Technology

Gilead and Aelix first teamed up in 2018 for a clinical research collaboration agreement to investigate the vaccine.

Vaccine 246

More Trending

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Amgen obesity drug cuts weight in study, but results miss Wall Street’s high mark

Bio Pharma Dive

Shares in Amgen fell by double digits Tuesday on results for the company’s MariTide shot, which is viewed as a potential rival to Wegovy and Zepbound.

Drugs 219
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Pharmaceutical Technology Excellence Awards 2024: PCI Pharma Services 

Pharmaceutical Technology

PCI Pharma Services is a winner in the Innovation and Business Expansion categories in the 2024 Pharmaceutical Technology Excellence Awards.

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Roche to buy cell therapy developer Poseida for $1B

Bio Pharma Dive

The deal suggests Roche sees substantial promise in Poseida’s technology, as the offer is 215% above the biotech’s closing share price on Monday.

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NHS rolls out monoclonal antibody treatment for rare bone disease  

Pharmaceutical Technology

The NHS will provide the monoclonal antibody Crysvita at 20 specialist centres across England for patients with XLH.

Antibody 130
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Transforming pharmacovigilance: The revolutionary impact of generative AI on drug safety

pharmaphorum

Discover the revolutionary impact of generative artificial intelligence (GenAI) on drug safety in pharmacovigilance. Learn how this cutting-edge technology is transforming the industry.

Drugs 118
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Eton acquires US rights to neonatal diabetes treatment from AMMTeK

Pharmaceutical Technology

Eton has acquired the rights in the US to Amglidia for neonatal diabetes mellitus, from French biotechnology company AMMTeK.

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Moderna’s missteps spotlight PMCPA’s role in upholding pharma ethics

pharmaphorum

Moderna's missteps serve as a reminder of the importance of regulatory bodies like PMCPA in upholding ethics within the pharmaceutical industry. Learn more about their role and impact.

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Roche’s tiragolumab flops in another Phase III lung cancer trial

Pharmaceutical Technology

Tiragolumab missed the chance to prove a survival benefit in SKYSCRAPER-01 adding to previous trial failures for the anti-TIGIT therapy.

Trials 130
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Optimizing Clinical Supply Strategy: Navigating Challenges & Finding Your Ideal Model

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Biden ramps up Medicare coverage of obesity drugs

pharmaphorum

Outgoing US President Joe Biden has proposed a dramatic expansion of Medicare coverage of obesity drugs, but will the plan see the light of day?

Drugs 111
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Roche to acquire Poseida Therapeutics for $1.5bn

Pharmaceutical Technology

Roche has signed an agreement for the acquisition of Poseida Therapeutics in a deal representing a total value of up to $1.5bn.

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Medigene axes staff and refocuses its TCR pipeline

pharmaphorum

Medigene slashes staff and delays trials of its lead TCR therapy candidate as it refocuses its pipeline.

Trials 111
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Shorla Oncology’s IMKELDI approved by FDA for leukaemia cancers

Pharmaceutical Technology

The Food and Drug Administration (FDA) has approved Shorla Oncology‘s IMKELDI for the treatment of specific leukaemia cancer forms.

Drugs 130
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The New Age of Decentralized Clinical Trials

White paper that delves into the complex topic of Decentralized Clinical Trials and how to master them within the confines of FDA Regulations

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Roche buys off-the-shelf CAR-T player Poseida for $1bn

pharmaphorum

Roche has upgraded its partnership with off-the-shelf CAR-T therapy specialist Poseida to a $1 billion-plus takeover bid.

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Shorla gains FDA nod for first oral liquid version of Novartis' Gleevec

Fierce Pharma

In 2001, a Time Magazine cover story touted Novartis’ targeted leukemia treatment Gleevec (imatinib) as a new kind of “am | Shorla Oncology has scored an FDA approval for its strawberry-flavored drink version of Novartis' cancer drug Gleevec. Dubbed Imkeldi, it becomes the first oral liquid form of imatinib.

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MSD adds rocket fuel to Winrevair's engine in PAH

pharmaphorum

ZENITH trial of MSD's Winrevair in PAH could add further momentum to an already impressive launch.

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Time to manage dengue with multi-faceted approach

Fierce Pharma

| Takeda is focused on curbing dengue with innovative solutions and public-private partnerships to achieve the WHO’s goal of zero dengue deaths by 2030.

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European Clinical Supply Planning: Balancing Cost, Flexibility and Time

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End looms for Cassava's simufilam in Alzheimer's disease

pharmaphorum

Cassava Sciences' troubled development of Alzheimer's disease candidate simufilam looks like it may have finally reached the end

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Drug Patent Expirations for the Week of November 24, 2024

Drug Patent Watch

ACULAR LS (ketorolac tromethamine) Abbvie Patent: 8,377,982 Expiration: Nov 28, 2024 See More … Source

Drugs 52
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Beyond Data Collection: How Modern EDC Systems Are Becoming Clinical Intelligence Hubs

Crucial Data Soutions

For years, electronic data capture (EDC) systems have been the backbone of clinical trials, efficiently collecting and managing study data. The post Beyond Data Collection: How Modern EDC Systems Are Becoming Clinical Intelligence Hubs appeared first on Crucial Data Solutions.

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CAR-T therapies: Faster, better, cheaper

pharmaphorum

Tune in to this podcast episode featuring an interview with Phil Johnson from Interius Biotherapeutics as he discusses the latest advancements in CAR-T therapies, focusing on faster, better, and cheaper treatments.

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The New Age of Decentralized Clinical Trials

This new white paper defines and details the impact of Decentralized Clinical Trials on the Pharmaceutical industry and how the impact can be measured along with steps companies can take to ensure adoption.

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Technically Speaking: Quality Documentation is One of the Best Ways to Boost Performance

Pharmaceutical Commerce

Why well-organized documentation is critical at every stage of the process.

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15th World ADC London 2025

pharmaphorum

Join the 15th World ADC London event organized by Hanson Wade in 2025. Explore the latest advancements in antibody-drug conjugates and network with industry experts.

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How Leaders Can Foster Proactive and Reactive Change

Pharmaceutical Commerce

In the final part of his video interview with Pharma Commerce Editor Nicholas Saraceno, Gaurav Gupta, managing director and head of R&D at Kotter, offers advice for effectively being able to adjust plans.

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DIA Global Meeting 2025

CTTI (Clinical Trials Transformation Initiative)

Presentation: Building Upon Quality by design and Risk-based Monitoring Implementation Momentum Date: Wednesday, June 18, 8:30 – 9:30 a.m. Presenter: Gerrit Hamre (Duke University), Morgan Hanger (CTTI), Sameera Ibrahim (Bristol Myers Squibb), and Alissa Munn (Food and Drug Administration/CDER) The post DIA Global Meeting 2025 appeared first on CTTI.

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Unlocking Excellence: How Catalent Is Transforming Japan’s Clinical Research

Planning on running clinical trials in Japan? How can you reliably supply these studies? Discover Catalent’s clinical supply packaging facility in Shiga, Japan. Strategically located between Tokyo and Osaka, and one of largest in Japan, this 6,000 square meter facility offers comprehensive services including primary and secondary clinical packaging and labelling, comparator sourcing, cold chain storage, local and global distribution, local language support and white glove service to support stud