Tue.Mar 18, 2025

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March 18, 2025: ABATE Infection Analysis Explores Cost-Effectiveness of Strategies to Prevent Hospital-Acquired Infections

Rethinking Clinical Trials

In a cost-effectiveness analysis using data from the ABATE Infection trial, a strategy of chlorhexidine bathing and nasal decolonization targeted to hospitalized adults with medical devices in nonintensive care unit (ICU) settings was cost-effective in reducing hospital-acquired infections. The study results were published this month in JAMA Network Open.

Allergies 146
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AstraZeneca and Alteogen agree on ALT-B4 platform tech

Pharmaceutical Technology

AstraZeneca has entered an exclusive licence agreement with Alteogen involving the latters ALT-B4 platform technology.

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Stoke CEO exits; Medicare drug price talks advance

Bio Pharma Dive

Ed Kaye, Stoke’s longtime leader, will be replaced by former Vertex executive Ian Smith. Elsewhere, all 12 drugmakers targeted for second round of Medicare price talks agreed to participate.

Drugs 269
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Health Canada approves Biogen’s Skyclarys for Friedreich’s ataxia

Pharmaceutical Technology

Health Canada has granted approval for Biogens Skyclarys to treat Friedreichs ataxia (FA) in individuals aged 16 years and above.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Duchenne patient dies after receiving Sarepta gene therapy

Bio Pharma Dive

A young man treated with Elevidys died of acute liver failure. The case may give doctors pause before prescribing the treatment in the future, some analysts wrote.

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Big tech meets biotech: Recursion and the AI gold rush in pharma 

Pharmaceutical Technology

The use of AI in drug discovery and development has been recognised, explored, and implemented throughout the last decade, with a notable acceleration in recent years.

More Trending

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FDA Cautions Hemodialysis Tubing Shortage Could Persist into Fall

XTalks

The FDA has issued a letter addressed to healthcare providers warning that the ongoing shortage of hemodialysis bloodlines may extend into the autumn months. Also referred to as dialysis catheters, hemodialysis bloodlines are sets of tubes inserted into a vein during dialysis treatment. They connect the patients bloodstream to the dialysis machine, which filters the blood to remove waste and excess fluid in patients with impaired kidney function.

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Arbor raises $74M amid genetic medicine’s funding slump

Bio Pharma Dive

The round will fund a “one-and-done” treatment for a rare kidney condition that its CEO says can address concerns patients have with therapies from Alnylam and Novo Nordisk.

Genetics 184
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Povorcitinib Phase III Results Stir Mixed Signals for Incyte and Investors

XTalks

Incytes recent announcement on the topline results from two Phase III clinical trials of povorcitinib in patients with hidradenitis suppurativa has stirred both hope and caution in the market. Hidradenitis suppurativa affecting roughly 1% of the population is a chronic skin condition marked by painful boils and abscesses that can significantly disrupt daily life.

Trials 59
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The Issue with Reissue: PTE Edition

FDA Law Blog

By Sara W. Koblitz Integral to the careful balance Congress struck when passing the Hatch-Waxman Amendments, the patent term extension (PTE) is intended to restore patent life that was consumed during regulatory review of an FDA-regulated product. Even though the PTE provisions established in the Drug Price Competition and Patent Restoration Act are forty-plus years old, courts are still grappling with questions about how to best implement the Patent Term Extension.

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Optimizing Clinical Supply Strategy: Navigating Challenges & Finding Your Ideal Model

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Opko and Entera focus on oral care for obesity and metabolic disorders

Pharmaceutical Technology

Opko Health and Entera Bio have announced a partnership and licence agreement to progress the development of oral dual agonist GLP-1.

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Sofinnova’s latest biotech fund sprouts three new startups

Bio Pharma Dive

As part of its “pan-European” plans, Sofinnova is backing startups developing treatments for fibrosis, cancer and Alzheimer’s.

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The Digital Determinants of Health: Shaping the Future of Well-Being

Intouch Solutions

In our latest POV by Roberto Ascione, President of EVERSANA INTOUCHs Health Innovation, and Ferdinando Scala, Director of Strategic Planning, the evolving landscape of digital health and its implications for the life sciences industry are explored with an emphasis on the importance of understanding digital determinants of health, which include factors such as internet access, digital literacy, and the availability of digital devices.

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Ready or Not, it’s Time to Take AI in Clinical Research Seriously

ACRP blog

Consumers of popular culture in the 1960s and 1970s preferred their artificial intelligence (AI) to come with overtones of danger, if not outright world domination, judging by small- and large-screen science fiction artifacts ranging from episodes of the original Star Trek series to movies like 2001: A Space Odyssey and Colossus: The Forbin Project.

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The New Age of Decentralized Clinical Trials

White paper that delves into the complex topic of Decentralized Clinical Trials and how to master them within the confines of FDA Regulations

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Faba Bean Protein: Overcoming Formulation Challenges in Protein-Enriched Food Applications

XTalks

In today’s food and beverage industry, protein enrichment has become a pivotal trend, driven by consumers’ growing awareness of health and nutrition. High-protein products are in demand across various categories, from bakery and dairy (alternatives) to sports nutrition and savoury foods. Incorporating additional protein into products presents several challenges for manufacturers.

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Looking at Images of Nature Does Something Powerful in The Brain

AuroBlog - Aurous Healthcare Clinical Trials blog

(Ippei Naoi/Getty Images) Simply looking at nature or even just digital pictures of it can relieve pain, according to new research which scanned the brains of people receiving electrical shocks. Nature’s many health benefits have been documented by decades of research.

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Curevo procures $110m and former-GSK exec for shingles vaccine candidate

Pharmaceutical Technology

GSKs shingles vaccine Shingrix passed $1bn in sales last year as Curevo aims to grasp market share.

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The Growing Importance of Generic Drug Development for Emerging Markets

Drug Patent Watch

Breaking Down Barriers to Affordable Healthcare As we navigate the complex landscape of global healthcare, one thing is clear: access to affordable medications is a fundamental human right. In emerging markets, the struggle to provide quality healthcare is often hindered by the high cost of branded medications. This is where generic drug development comes in a game-changer for millions of people around the world.

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European Clinical Supply Planning: Balancing Cost, Flexibility and Time

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NOW AVAILABLE: The 2025 Economic Report on U.S. Pharmacies and Pharmacy Benefit Managers

Drug Channels

I am pleased to announce that Drug Channels Institutes new 2025 Economic Report on U.S. Pharmacies and Pharmacy Benefit Managers is now available for purchase and immediate download. Download a free 30-page report overview including key industry trends, What's New in this edition, the Table of Contents, and a List of Exhibits Read the press release: HMP Globals Drug Channels Institute Releases 2025 Economic Report on U.S.

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Inside the Russian Pharma Industry: Key Players and Innovations

Drug Patent Watch

Exploring the Russian Pharma Industry: Key Players and Innovations As we continue to navigate the complexities of the global pharmaceutical landscape, it's essential to stay informed about emerging markets and trends. Today, I want to take you on a journey to Russia, a country with a rich history of pharmaceutical innovation and a growing presence in the industry.

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NHS medicines spending in England in greater focus

pharmaphorum

Stay informed about the latest information on NHS medicines spending in England, with a greater focus on the data provided by the NHS Business Services Authority (NHBSSA).

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UKHSA announces new effort to tackle hepatitis C

Pharma Times

The agency has launched a whole genome sequencing service to monitor the virus

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The New Age of Decentralized Clinical Trials

This new white paper defines and details the impact of Decentralized Clinical Trials on the Pharmaceutical industry and how the impact can be measured along with steps companies can take to ensure adoption.

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Novo Nordisk returns to ABPI fold after two-year suspension

pharmaphorum

Novo Nordisk has reached the end of its two-year suspension from the ABPI for breaches of its code of practice after making "sustained improvements"

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Access USA 2025: This Year’s State of the Industry

Pharmaceutical Commerce

The conferences opening session highlights the sectors current landscape of healthcare coverage and access.

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Sofinnova closes new fund and backs a trio of new biotechs

pharmaphorum

Sofinnova Partners has raised 165m for its new biotech fund and backed three startups working on Alzheimer's, fibrotic diseases, and cell therapies

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FDA Validation Rules for Submission Data: Avoid Costly Mistakes!

ProRelix Research

FDA Validation Rules for Submission Data are essential for regulatory compliance. Learn about FDA data submission requirements, validator rules, study data standardization plans, and Pinnacle 21 validation. Stay updated with […] The post FDA Validation Rules for Submission Data: Avoid Costly Mistakes! appeared first on ProRelix Research.

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Unlocking Excellence: How Catalent Is Transforming Japan’s Clinical Research

Planning on running clinical trials in Japan? How can you reliably supply these studies? Discover Catalent’s clinical supply packaging facility in Shiga, Japan. Strategically located between Tokyo and Osaka, and one of largest in Japan, this 6,000 square meter facility offers comprehensive services including primary and secondary clinical packaging and labelling, comparator sourcing, cold chain storage, local and global distribution, local language support and white glove service to support stud

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AstraZeneca buys cell therapy biotech for up to $1bn

pharmaphorum

AstraZeneca plans to acquire Belgian in vivo cell therapy biotech EsoBiotec and has signed a pair of licensing deals with drug delivery firm Alteogen.

In-Vivo 66
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How Demographics Shape Patient Recruitment Strategies in Clinical Trials

Antidote

Recruiting patients for clinical trials is not a one-size-fits-all process. Demographicsfactors like age, gender, race, socioeconomic status, and geographic location influence who enrolls, who stays, and how well trial results translate into real-world treatments.

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Vertanical's cannabis-based painkiller hits target in trials

pharmaphorum

A cannabis-derived drug developed by Vertanical has shown efficacy in phase 3 for chronic back pain and could reach its first markets soon

Trials 66
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How Pharma Leaders Can Secure Supply Chains

Pharmaceutical Commerce

In the third part of his video interview with Pharma Commerce Editor Nicholas Saraceno, Brad Stewart, BDOs national life sciences co-leader, outlines the ways that tariffs disrupt pharma supply chains, along with how leaders can evaluate and prepare for the resulting challenges.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.