Sun.Feb 16, 2025

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Buprenorphine, Pain, and Opioid Use in Patients Taking High-Dose Long-Term Opioids

JAMA Internal Medicine

This randomized clinical trial evaluates optionally switching to buprenorphine as a strategy for improving pain and reducing opioids among patients prescribed high-dose, full agonist long-term opioid therapy.

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Strategies for successful biosimilar-to-biosimilar switching

Drug Patent Watch

The Future of Biosimilars: Switching Strategies for Success As the biosimilar market continues to grow, pharmaceutical companies are looking for innovative ways to stay ahead of the competition. One strategy that's gaining traction is biosimilar-to-biosimilar switching. But what does this mean, and how can you make it work for your business? Biosimilar-to-biosimilar switching involves switching patients from one biosimilar to another, often to improve efficacy, reduce costs, or enhance patient o

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Diagnosis and Management of Monoclonal Gammopathy of Undetermined Significance

JAMA Internal Medicine

This Review summarizes evidence on the diagnosis and management of monoclonal gammopathy of unknown significance to guide clinical decision-making.

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