Fri.Jan 24, 2025

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Light-activated ink developed to remotely control cardiac tissue to repair the heart

Medical Xpress

Researchers from Mass General Brigham and collaborating institutions have developed a non-invasive approach to manipulate cardiac tissue activity by using light to stimulate an innovative ink incorporated into bioprinted tissue. Their goal is to develop a technique that can be used to repair the heart. Their findings in preclinical models, published in Science Advances, show the transformative potential of non-invasive therapeutic methods to control electrically active tissues.

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Purdue and Sackler family agree to $7.4bn national opioid settlement

Pharmaceutical Technology

The settlement ends the Sackler familys ownership of the Oxycontin developer Purdue Pharma.

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Sara Brenner, FDA device official, named agency’s acting head

Bio Pharma Dive

Brenner, who has worked in the FDA’s Center for Devices and Radiological Health, will lead the agency until a permanent commissioner is confirmed.

Radiology 245
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Stealth faces another hurdle as FDA delays decision on Barth syndrome drug

Pharmaceutical Technology

The FDA rejected the companys initial NDA in 2021, citing the lack of an adequate trial to demonstrate efficacy.

Drugs 255
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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva Health Inc.

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Novo shares climb on early data for dual-acting obesity drug

Bio Pharma Dive

An experimental drug called amycretin showed signs it could be more potent than Eli Lilly’s rival Zepbound, though analysts cautioned certain aspects of the study may have inflated its performance.

Drugs 179
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MS Drugs Copaxone and Glatopa Get FDA Boxed Warnings for Anaphylaxis

XTalks

The FDA has updated the labeling for glatiramer acetate , used for the treatment of multiple sclerosis (MS), to include a boxed warning about the risk of the allergic reaction anaphylaxis. The drug is marketed by Teva Pharmaceuticals as Copaxone and Sandoz sells a generic version of it under the name Glatopa. According to the FDA, cases of anaphylaxis which can be life-threatening in severe cases and if not treated in a timely or effective manner have been reported in patients treated with gla

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Scientists uncover how cancer cells hijack T-cells, making it harder for the body to fight back

Medical Xpress

Research led by the Chiba Cancer Center Research Institute in Japan has discovered a surprising way cancer evades the immune system. It essentially hacks the immune cells, transferring its own faulty mitochondrial DNA (mtDNA) into the T-cells meant to attack it.

DNA 107
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FDA approves drug application for Lupin’s heart failure therapy

Pharmaceutical Technology

The FDA has granted approval for the ANDA of Lupins Sacubitril and Valsartan Tablets for heart failure patients.

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UnitedHealth names CEO to replace slain Thompson

pharmaphorum

UnitedHealth has appointed company veteran Tim Noel as CEO of its UnitedHealthcare insurance unit, after the murder last month of Brian Thompson.

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Emcure Pharmaceuticals opens new R&D centre in Gujarat, India

Pharmaceutical Technology

Emcure Pharmaceuticals has opened its new formulation research and development (R&D) centre at Ahmedabad, in the Indian state of Gujarat.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Purdue and Sacklers agree new $7.4bn opioid settlement

pharmaphorum

Purdue Pharma and the Sackler family who own the company have proposed a new $7.

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AbbVie and Neomorph link on oncology/immunology glue degraders

Pharmaceutical Technology

AbbVie and Neomorph are set to enter a partnership and option-to-license agreement to develop molecular glue degraders.

Licensing 147
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Pharmacy benefits: Lessons from 2024 and what lies ahead for 2025

pharmaphorum

Explore the lessons learned from 2024 in pharmacy benefits, including the impact of polypharmacy, biosimilars, and GLP-1 medications, and what to expect for 2025 in this insightful article.

Pharmacy 100
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Podcast: Adaptive logistics in a changing clinical landscape

Pharmaceutical Technology

Adaptive logistics are vital for clinical trials, but there are challenges in navigating complexities of regulations and quality standards.

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Optimizing Clinical Supply Strategy: Navigating Challenges & Finding Your Ideal Model

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Targeting potassium channel shows promise for treating brain tumors in children

Medical Xpress

Scientists at The Hospital for Sick Children (SickKids) have identified a key gene that could lead to next-generation treatments for medulloblastoma, the most common malignant brain tumor in children.

Gene 99
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Novo Nordisk leaps on new obesity drug data

pharmaphorum

Shares in Novo Nordisk have risen sharply on new weight-loss data with an injectable formulation of new obesity candidate amycretin.

Drugs 95
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VR subway experiment highlights role of sound in disrupting balance for people with inner ear disorder

Medical Xpress

The vestibular system is a network of organs in the inner ears that detects the motions and position of the head. The brain uses this information, along with inputs from the eyes and joints, to maintain the body's balance.

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AstraZeneca reveals $570m investment in Canada

pharmaphorum

AstraZeneca has announced another major investment in Canada, tapping into the country's emergence as a "global hub" for clinical trials.

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The New Age of Decentralized Clinical Trials

White paper that delves into the complex topic of Decentralized Clinical Trials and how to master them within the confines of FDA Regulations

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Mapping the brain's self-healing abilities after stroke

Medical Xpress

A new study by researchers at the Department of Molecular Medicine at SDU sheds light on one of the most severe consequences of stroke: damage to the brain's "cables"the so-called nerve fiberswhich leads to permanent impairments. The study, published in The Journal of Pathology, which is based on unique tissue samples from Denmark's Brain Bank located at SDU, may pave the way for new treatments that help the brain repair itself.

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2025 digital transformation budgets: Realigning expectations

pharmaphorum

Learn how companies are rethinking their digital transformation budgets for 2025 and realigning expectations to effectively leverage technology for business growth.

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Neurons in amygdala found to regulate social behavior with strangers

Medical Xpress

Researchers at the University of Tsukuba have identified neurons that are essential for mice to engage in social interactions with novel individuals.

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Neko Health raises $260m for its bid to transform healthcare

pharmaphorum

Spotify founder Daniel Ek's new business Neko Health has raised $260m to bring its body scanning clinics to new international markets

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European Clinical Supply Planning: Balancing Cost, Flexibility and Time

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Study finds OCD patients' decision making mirrors general population

Medical Xpress

Although obsessive compulsive disorder (OCD) can be treated, research has shown that people with the disorder tend to have a lower quality of life than neurotypical people. Many struggle to achieve the same levels of education and financial stability as people without the disorder.

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Pharma Pulse 1/24/25: The Ups and Downs of AI for Pharma Investors, Defining Diagnostic Criteria for Clinical Obesity & more

Pharmaceutical Commerce

The latest news for pharma industry insiders.

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Personalized therapy for rare genetic diseases: Patient-derived organoids offer new hope

Medical Xpress

Children's Mercy Kansas City has achieved a significant advancement toward the treatment of rare genetic diseases through the use of personalized antisense oligonucleotides (ASOs). This innovative approach has shown promising results in preclinical evaluations, which offers new hope for patients with previously untreatable conditions and validates personalized therapies for patients in only eight weeks, significantly faster and more cost-effective than the industry average.

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How Trade Strategy Impacts Business Success

Pharmaceutical Commerce

In the second part of her video interview with Pharma Commerce Editor Nicholas Saraceno, Amanda Salindong, associate director of channel & distribution at Alnylam Pharmaceuticals, describes how she supports her organizations channel strategy.

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The New Age of Decentralized Clinical Trials

This new white paper defines and details the impact of Decentralized Clinical Trials on the Pharmaceutical industry and how the impact can be measured along with steps companies can take to ensure adoption.

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Researchers pinpoint keys to cell therapy response for leukemia

Medical Xpress

Dana-Farber Cancer Institute researchers have identified factors that determine whether donor lymphocyte infusion (DLI), a standard therapy for patients with acute myeloid leukemia (AML) who have relapsed after allogenic hematopoietic stem cell transplant, will successfully move the patient into remission. The team identified that a key cell type in the DLI product and features of the tumor microenvironment in patients both play a role.

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JP Morgan Week 2025 - Fabrizio Chines

pharmaphorum

Learn more about JP Morgan Week 2025 and gain insight into Fabrizio Chines through an exclusive video interview. Discover valuable information shared during this exciting event.

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Researchers train AI to diagnose lung diseases with 96.57% accuracy

Medical Xpress

Artificial Intelligence (AI) could become a radiologist's best friend, with researchers training the technology to accurately diagnose pneumonia, COVID-19 and other lung diseases.

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Social media advocacy: Healthcare professionals and the Treat and Reduce Obesity Act

pharmaphorum

Learn how healthcare professionals (HCPs) can utilise social media advocacy to support the Treat and Reduce Obesity Act. Discover effective strategies and tips for engaging with legislators and promoting awareness of obesity-related initiatives.

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Unlocking Excellence: How Catalent Is Transforming Japan’s Clinical Research

Planning on running clinical trials in Japan? How can you reliably supply these studies? Discover Catalent’s clinical supply packaging facility in Shiga, Japan. Strategically located between Tokyo and Osaka, and one of largest in Japan, this 6,000 square meter facility offers comprehensive services including primary and secondary clinical packaging and labelling, comparator sourcing, cold chain storage, local and global distribution, local language support and white glove service to support stud