BioTech 365

APRIL 9, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: New, reversible CRISPR method can control gene expression while leaving underlying DNA sequence unchanged.Over the past decade, the CRISPR-Cas9 gene editing system has revolutionized genetic engineering, allowing … Continue (..)

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Gene Expression DNA Gene Editing Gene 40

XTalks

AUGUST 5, 2020

Visium Spatial Gene Expression Solution. To address challenges associated with loss of spatial context, 10x Genomics has developed the Visium Spatial Gene Expression solution, which enables answering biological questions in the context of tissue using an unbiased gene expression approach.

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Gene Expression Development RNA Drugs 112

Scienmag

NOVEMBER 26, 2020

For the first time, researchers describe how Rho protein really stops gene expression COLUMBUS, Ohio – New research has identified and described a cellular process that, despite what textbooks say, has remained elusive to scientists until now – precisely how the copying of genetic material that, once started, is properly turned off.

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Gene Expression Genetics Protein Gene 54

pharmaphorum

JANUARY 29, 2021

Since that discovery, a flurry of gene-editing focused biopharma companies have launched – including Intellia Therapeutics, CRISPR Therapeutics, Caribou Biosciences and Mammoth Biosciences – and the first drug therapies based on the technology are now in human testing for diseases like cancer.

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Gene Editing Gene Gene Therapy In-Vivo 145

XTalks

MAY 4, 2021

These modifications regulate gene expression without changing the sequence or structure of DNA. Now we have a simple tool that can silence the vast majority of genes,” said Jonathan Weissman, PhD, Whitehead Institute member, co-senior author of the new paper and a former UCSF faculty member in a statement from UCSF. “We

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DNA Gene Gene Silencing Genomics 98

XTalks

OCTOBER 8, 2024

XTALKS WEBINAR: Measuring Intact mRNA and 5’ Capping Efficiency in One Assay Live and On-Demand: Thursday, October 17, 2024 , at 12pm EDT ( 9am PDT ) Register for this free webinar to learn about a multiplexed imaging platform that is engineered to address needs in mRNA and vaccine drug product characterization.

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Regulation Genetics Scientist RNA 52

pharmaphorum

JANUARY 13, 2022

The UK-headquartered pharma is buying into a drug discovery platform developed by Boston, US biotech Scorpion Therapeutics, paying $75 million upfront to get the ball rolling on the partnership, with undisclosed option fees and milestone payments also on offer.

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Protein Gene Expression Gene Regulation 59

Roots Analysis

AUGUST 31, 2023

The two types of gene regulation have been discussed below: Positive Gene Regulation: Activator is a protein molecule that helps to initiate a positive gene regulation. When activator binds to the operon, it either speeds up or permits gene expression.

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XTalks

MARCH 22, 2021

The biotech acquisition will also see Takeda getting Maverick’s TAK-280 (MVC-280), an immunotherapy designed to treat patients with B7H3-expressing solid tumors which is expected to enter the clinic later this year. Both of Biotheranostics’ diagnostics are PCR-based gene expression tests.

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Life Science Development Marketing Gene Expression 110

XTalks

MAY 4, 2021

These modifications regulate gene expression without altering the sequence or structure of DNA. Now we have a simple tool that can silence the vast majority of genes,” said Jonathan Weissman, PhD, Whitehead Institute member, co-senior author of the new paper and a former UCSF faculty member in a statement from UCSF. “We

DNA 52

DNA Gene Gene Silencing Genomics 52

XTalks

JUNE 18, 2024

c-srRNA: A Temperature-Controllable Innovation Elixirgen Therapeutics’ c-srRNA platform offers a novel approach to controlling gene expression through temperature sensitivity. The essence of the c-srRNA platform lies in its innovative use of temperature as a regulatory mechanism.

Protein 52

Protein RNA Genetics Gene Expression 52

Roots Analysis

OCTOBER 22, 2023

Coding RNAs include messenger RNA (mRNA) and short interfering RNA (siRNA), which encode proteins and silence gene expression, respectively. It is important to highlight that IVT mRNAs are structurally similar to natural mRNAs and can be used to express proteins through genetic engineering.

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RNA Protein Genetics Gene Expression 40

The Pharma Data

JANUARY 19, 2021

Fulcrum’s proprietary product engine identifies drug targets which can modulate gene expression to treat the known root cause of gene mis-expression.

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Gene Expression Containment Genetics Clinical Development 40

The Pharma Data

DECEMBER 27, 2020

STP705 is a small interfering RNA (siRNA) therapy that leverages a dual-targeted inhibitory property and polypeptide nanoparticle (PNP)-enhanced delivery to knock down both TGF-beta1 and COX-2 gene expression. GA Depot is a long-acting injection of the approved Glatiramer Acetate products (Copaxone and its generic formulations).

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Trials Antibody Gene Therapy Gene 52

XTalks

DECEMBER 24, 2020

While technologies such as fluorescence-activated cell sorting (FACS) have allowed for profiling intracellular and cell surface markers in single cells, analyzing gene expression at the single cell level was previously not possible. The first step in most single-cell analysis techniques involves the isolation of individual cells.

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The Pharma Data

MAY 13, 2021

Journal of Food Engineering. Opiate-like effects of sugar on gene expression in reward areas of the rat brain. Raghavendra SN, Ramachandra SSR, Rastogi NK, Raghavarao KSMS, Kumar S, Tharanathan RN. Grinding characteristics and hydration properties of coconut residue: A source of dietary fiber. 2006;72(3):281-286. 2004.12.008. .

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