Drug Discovery World

NOVEMBER 1, 2022

Splicing-linked expression design. Two methods currently used to deliver protein-making packages into cells, ‘mini promoters’ and serotype-mediated gene expression, vary widely. We wanted to develop a gene expression delivery tool that’s broadly useful in both preclinical and clinical models,” said Blackshaw. .

Gene Expression 52

Gene Expression Gene Protein Packaging 52

Drug Discovery World

FEBRUARY 27, 2024

BS: Genetic tuning, also called epigenetic editing, actively manipulates the epigenetic machinery to influence gene transcription. Orchestrating the naturally occurring conductors of gene expression can shift the functional state of cells and alter gene expression.

Gene Expression 59

Gene Expression DNA Genetics Gene 59

XTalks

AUGUST 5, 2020

The detailed complexity of these processes can be captured by creating models that combine correlates of gene and protein expression, providing insight into the molecular composition of tissues. Visium Spatial Gene Expression Solution. Feature barcoding using gel beads. Leading Innovations in Single Cell Technology.

Gene Expression 112

Gene Expression Development RNA Drugs 112

pharmaphorum

JANUARY 29, 2021

Genome editing is an exciting but still nascent field, and companies in the area face as many obstacles as they do opportunities. Then over the next two or three years, gene therapy was accepted as something that companies got involved in, and several biotechs have been bought up by big pharma.”.

Gene Editing 141

Gene Editing Gene Gene Therapy In-Vivo 141

Drug Discovery World

DECEMBER 12, 2022

Dr Ramakrishnan, who holds a Bachelor of Biotechnology and Biochemical Engineering from the University of Kerala in India, presented a proposal examining microbiome-based therapeutics for asthma. . The study advances our understanding of ADHD by showing how the condition is tied to changes in how certain genes are expressed in the brain.

Drugs 52

Drugs Gene Editing Genome Genomics 52

XTalks

JUNE 18, 2024

c-srRNA: A Temperature-Controllable Innovation Elixirgen Therapeutics’ c-srRNA platform offers a novel approach to controlling gene expression through temperature sensitivity. EXG-34217 is an autologous cell therapy, meaning it uses the patient’s own cells, modified to express ZSCAN4 and thereby extend their telomeres.

Protein 52

Protein RNA Genetics Clinical Trials 52

XTalks

MAY 4, 2021

These modifications regulate gene expression without changing the sequence or structure of DNA. The tool could also prove to be safer than conventional CRISPR-based gene therapies as it does not involve DNA editing, and thus would not cause potentially harmful off-target genomic changes. Epigenetic Editing with CRISPR.

DNA 98

DNA Gene Gene Silencing Genome 98