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How Potential Changes to the NIH Guidelines Could Impact IBC Review

WCG Clinical

This change expanded the definition of HGT research to include research using nucleic acids that are able to replicate, be transcribed, translated into protein, and/or integrate into the host genome. Since then, however, certain genetic engineering technologies (e.g.,

Genome 52
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Advancements in upstream CLD for enhanced biotherapeutics production

Drug Discovery World

Upstream cell line development has seen notable progress with recent advances in cell line engineering, particularly in enhancing gene of interest integration specificity, clone selection, and production efficiency. Next-generation engineering tools, such as gene editing have enabled knock-out cell lines with enhanced characteristics.

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Precision Fermentation Study May Revolutionize Food Quality and Sustainability

XTalks

The precision fermentation study highlights how genetically engineered microorganisms can inhibit the growth of foodborne pathogens. Words like “bioengineered” and “genetically modified” often provoke negative reactions. This not only extends the shelf life of foods but also ensures they are safer for consumption.

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Colorectal Cancer Awareness Month 2024: Innovations in Treatment

XTalks

Gene Editing and CAR T-Cell Therapy Genetic engineering technologies, such as CRISPR-Cas9, are providing newer potential avenues for cancer treatment. Tukysa (tucatinib) plus Herceptin (trastuzumab): The FDA has approved this treatment for certain individuals with CRC characterized by overexpression of HER2 proteins in their tumors.

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New gene-editing tool is more accurate than CRISPR

Drug Discovery World

SeekRNA’s ability to target selection with precision and flexibility sets the stage for a new era of genetic engineering, surpassing the limitations of current technologies,” Dr Ataide said. Dr Ataide added: “SeekRNA can precisely cleave the target site and insert the new DNA sequence without the use of any other proteins.

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Leading innovators in transcription factors for AAV for the pharmaceutical industry

Pharmaceutical Technology

AAV genomes are highly compact, with overlapping coding regions, alternate splicing schemes, and multiple transcription initiation codons. There are two main genes in the AAV genome, rep and cap, which encode nine different proteins. Transcription of the cap gene is initiated from a single promoter termed p40.

Gene 262
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Bringing in Light Genome Editing Techniques: ZFN, TALEN and Meganucleases

Roots Analysis

Gene engineering based on recombination was pioneered in the mid-1990s; Currently, development of gene editing technologies has opened up the possibility of modifying genomic sequences in both eukaryotic and prokaryotic organisms. Genome Editing is a way of making changes in the DNA. Type of Genome Editing: Zinc-Finger Nuclease.

Genome 52